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Full-Text Articles in Genetics and Genomics
Food Based Approaches For A Healthy Nutrition In Africa, Mamoudou Hama Dicko
Food Based Approaches For A Healthy Nutrition In Africa, Mamoudou Hama Dicko
Pr. Mamoudou H. DICKO, PhD
The latest estimates of the FAO demonstrate the problems of the fight against hunger. These problems are manifested by the ever-increasing number of chronically undernourished people worldwide. Their numbers during the 1999-2001 period were estimated at about 840 million of which 798 million live in developing countries. Sub-Saharan Africa alone represented 198 million of those. In this part of Africa the prevalence of undernourishment ranges from 5-34%, causing growth retardation and insufficient weight gain among one third of the children under five years of age and resulting in a mortality of 5-15% among these children. Malnutrition resulting from undernourishment is …
Expression Profiling Of Mammalian Micrornas Uncovers A Subset Of Brain-Expressed Micrornas With Possible Roles In Murine And Human Neuronal Differentiation., Lorenzo F. Sempere, Sarah Freemantle, Ian Pitha-Rowe, Eric Moss, Ethan Dmitrovsky, Victor R. Ambros
Expression Profiling Of Mammalian Micrornas Uncovers A Subset Of Brain-Expressed Micrornas With Possible Roles In Murine And Human Neuronal Differentiation., Lorenzo F. Sempere, Sarah Freemantle, Ian Pitha-Rowe, Eric Moss, Ethan Dmitrovsky, Victor R. Ambros
Victor R. Ambros
Background The microRNAs (miRNAs) are an extensive class of small noncoding RNAs (18 to 25 nucleotides) with probable roles in the regulation of gene expression. In Caenorhabditis elegans, lin-4 and let-7 miRNAs control the timing of fate specification of neuronal and hypodermal cells during larval development. lin-4, let-7 and other miRNA genes are conserved in mammals, and their potential functions in mammalian development are under active study. Results In order to identify mammalian miRNAs that might function in development, we characterized the expression of 119 previously reported miRNAs in adult organs from mouse and human using northern blot analysis. Of …