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- Genetic diversity (4)
- Genes (3)
- Biology (2)
- Chironomid hemoglobin (2)
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- New Jersey (2)
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- ApoAll Levels (1)
- Aurora kinase (1)
- Bacterioopsin gene (Bop) (1)
- Balbiani Ring (1)
- Bioinformatics (1)
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- Environmental Indicators and Impact Assessment (1)
- FVB/N wildtype Mice (1)
- GPCR characterization (1)
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- Halobacterium salinartum (H sal) (1)
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Articles 1 - 12 of 12
Full-Text Articles in Genetics and Genomics
Effects Of Aurora Kinase C Expression On Retina Pigmented Epithelial Cell Migration, Proliferation, And Anchorage Independent Growth, Justin Bejar
Seton Hall University Dissertations and Theses (ETDs)
Cancer is a common and deadly disease in the United States with 1,806,590 new cancer cases in 2019 and 606,520 cancer deaths projected in 2020. These deaths are primarily due to the uncontrolled cell proliferation and migratory nature of the disease. Many cancer cells express genes normally restricted to meiotic cells. For example, Aurora Kinase C (AURKC) is known to regulate chromosome segregation in meiotic cells yet it is expressed in many different types of cancer, such as breast, prostate, colorectal, liver, cervical, thyroid, and testicular cancers. As a means to study the function of AURKC, an …
Transcriptome Analysis Of Sea Lamprey Embryogenesis, Zakary Ilya Yermolenko
Transcriptome Analysis Of Sea Lamprey Embryogenesis, Zakary Ilya Yermolenko
Seton Hall University Dissertations and Theses (ETDs)
The sea lamprey (Petromyzon marinus) has survived throughout evolution for hundreds of millions of years. It is considered an invasive species to the Great Lakes that has caused dramatic changes in the ecosystem for fish communities resulting in the collapse of a fishing industry that was previously valued at billions of dollars. Successful management of the sea lamprey is essential to a sustainable fishing industry and biodiversity. Therefore sea lamprey embryos were studied at various stages of development by growing them in a simulated habitat. RNAs from adult female ovaries and embryos at different time points during embryogenesis …
The 5' Bop Gene Stem-Loop Sequence: Stability, Structure, And Function, Srikanth Tangelloju
The 5' Bop Gene Stem-Loop Sequence: Stability, Structure, And Function, Srikanth Tangelloju
Seton Hall University Dissertations and Theses (ETDs)
In pursuit of GPCR characterization, our lab chose to work with a model organism Halobacterium salinarum (H sal). This organism contains the bacterioopsin gene (bop), which encodes the protein precursor of the purple membrane protein bacterioopsin (Bop). The bacterioopsin gene (bop) was chosen as the reporter for the study. The putative stem-loop structure within the bop gene is considered to be a key component of the molecular machinery that regulates Bop synthesis. Previous work in our lab has indicated that single base pair disruptions dramatically reduced stem-loop stability (differential scanning calorimetry (DSC), circular dichroism (CD) and ultraviolet (UV) spectroscopy analysis). …
Evaluation Of Genetic Diversity In Wild Chironomid Populations Using Rapd And Hemoglobin Protein As Molecular Biomarkers, Virendrasinh N. Jadeja
Evaluation Of Genetic Diversity In Wild Chironomid Populations Using Rapd And Hemoglobin Protein As Molecular Biomarkers, Virendrasinh N. Jadeja
Seton Hall University Dissertations and Theses (ETDs)
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Chironomid Hemoglobin Genetic Diversity As An Indicator Of The New Jersey Hackensack Meadowlands Wetland Health, Lene Marie De Coursin Jacobs
Chironomid Hemoglobin Genetic Diversity As An Indicator Of The New Jersey Hackensack Meadowlands Wetland Health, Lene Marie De Coursin Jacobs
Seton Hall University Dissertations and Theses (ETDs)
Kearny Marsh located within the Hackensack Meadowlands is a freshwater wetland impacted by multiple environmental stressors from human activity. The marsh is located in the northeastern New Jersey metropolitan area. Chironomid larvae, aquatic larvae of midge fly, were analyzed from two Kearny Marsh sample sites, W9 and W22. A previous sediment analysis and toxicity study characterized heavy metal contaminants the marsh. The data results were applied in this thesis study to determine the correlation between environmental stressors and chironomid genetic diversity. Site W9 sediment was impacted by severe levels of total heavy metal contamination, whereas site W22 had just below …
Chironomid Hemoglobin Genetic Diversity As An Indicator Of The New Jersey Hackensack Meadowlands Wetland Health, Lene Marie De Coursin Jacobs
Chironomid Hemoglobin Genetic Diversity As An Indicator Of The New Jersey Hackensack Meadowlands Wetland Health, Lene Marie De Coursin Jacobs
Seton Hall University Dissertations and Theses (ETDs)
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Multiple Kh Domains Of Poly C Binding Protein Are Required For Its Trans-Activation On The Proximal Promoter Of The Mu-Opioid Receptor Gene, Adnan K. Malik
Multiple Kh Domains Of Poly C Binding Protein Are Required For Its Trans-Activation On The Proximal Promoter Of The Mu-Opioid Receptor Gene, Adnan K. Malik
Seton Hall University Dissertations and Theses (ETDs)
The mu-opioid receptor (MOR) has been shown to mediate morphine induced analgesia, addiction, and tolerance. The expression of the major product of the MOR (MOR-1) gene has been found to be driven by two promoters, a distal promoter and a proximal promoter. The proximal promoter region has been shown in previous studies to be the major promoter for the regulation of MOR gene transcription in the adult mouse brain and embryonic development. Recent studies have shown that single-stranded DNA binding proteins (such as Poly C Binding Protein) are involved in transcriptional regulation of mouse MOR gene. Poly C binding protein …
Genetic Diversity Of Balbiani Ring L Gene In Two Species Of Chironomus, Lola-Mae Palmer
Genetic Diversity Of Balbiani Ring L Gene In Two Species Of Chironomus, Lola-Mae Palmer
Seton Hall University Dissertations and Theses (ETDs)
Differences in genetic composition have been predicted among aquatic midge fly larva called chironomids. Although several genes including microsatellites and ribosomal protein genes have been explored in our lab, the gene that has so far been studied the most is the Balbiani Ring (BR) 1 gene. There are several genes in this family, including Balbiani Ring 2.1, 2.2 and 6. These BR genes are known to contain long arrays of tandemly repeated units with a ranked repeat organization (Paulsson et al.1992). This secretory protein gene forms a large puff located on polytene chromosome IV (Bentivegna et al., 1993). The gene …
Cloning Of Hsds Gene And Characterization Of The Protein From Haemophilus Influenzae Rd, Srividya Chalapatti
Cloning Of Hsds Gene And Characterization Of The Protein From Haemophilus Influenzae Rd, Srividya Chalapatti
Seton Hall University Dissertations and Theses (ETDs)
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Analysis Of Genetic Factors Affecting High Density Lipoprotein Levels And Apoall Levels In C57 B1/6j And Fvb/N Wildtype Mice Using A Qtl Mapping Approach, Judith Barrios
Seton Hall University Dissertations and Theses (ETDs)
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Studying The Expression Of A Novel Microsatellite Mrna In Chironomous Riparius, Mina Ranzurmal
Studying The Expression Of A Novel Microsatellite Mrna In Chironomous Riparius, Mina Ranzurmal
Seton Hall University Dissertations and Theses (ETDs)
The expression of a unique mRNA containing a microsatellite sequence was studied in C. riparius using differential display. First, the rnicrosatellite fragment was sequenced using Sanger's Sequencing method. The microsatellite cDNA contained 11 "ACA" repeats, 12 "AC" repeats, and 5 "CTC" repeats. Second, the affects of cadmium and heat shock on rnicrosatellite mRNA expression were studied. In cadmium experiments, larvae were exposed to low cadmium concentrations (0, 0.04, 0.4, and 4.0 mM) for 24 and 48 h and high cadmium concentrations (0, 1.0, 2.0, 4.0, 8.0, and 16.0 mM) for 48 h. The effects of cadmium on fed larvae at …
Developing A Gene Specific Probe For Phosphoenolpyruvate Carboxykinase Mrna, Stephen M. Kuntz
Developing A Gene Specific Probe For Phosphoenolpyruvate Carboxykinase Mrna, Stephen M. Kuntz
Seton Hall University Dissertations and Theses (ETDs)
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