Forest Sciences Commons^™

Antioxidant Properties And Aldose Reductase Inhibitory Potency Of Viscum Album L. Extracts: Experimental And Computational Insights, Bilal Akyüz, Bülent Şengül

Turkish Journal of Agriculture and Forestry

This study systematically investigates the antioxidant capacity and inhibitory impact of Viscum album L. plant extracts on the aldose reductase (AR) enzyme through a combined approach of in vitro and in silico methods. Various sections derived from distinct plant parts were examined, revealing potent inhibitory potential. Notably, the methanol extract sourced from the plant's stem displayed remarkable efficacy with an IC50 value of 0.156 µM. Total phenolic content and antioxidant capacity analyses were conducted, highlighting variations across plant parts and solvent types. Qualitative and quantitative phenolic compounds content in the extracts was also elucidated by LC-MS/MS analysis and it was …