Cell and Developmental Biology Commons^™

Hgs-3 The Influence Of A Tandem Cycling Program In The Community On Physical And Functional Health, Therapeutic Bonds, And Quality Of Life For Individuals And Care Partners Coping With Parkinson’S Disease, Leila Djerdjour, Jennifer L. Trilk

SC Upstate Research Symposium

Purpose Statement: Several studies have shown that aerobic exercise can have a positive impact on alleviating symptoms experienced by individuals with Parkinson's disease (PD). Despite this evidence, the potential benefits of exercise for both PD patients and their care partners (PD dyad) remain unexplored. This research project investigates the effectiveness, therapeutic collaborations, and physical outcomes of a virtual reality (VR) tandem cycling program specifically designed for PD dyads.

Methods: Following approval from the Prisma Health Institutional Review Board, individuals with PD were identified and screened by clinical neurologists. The pre-testing measures for PD dyads (N=9) included emotional and cognitive status …

Mc-02 Increased Wound Healing In P-Glycoprotein Deficient Intestinal Cells, Madison T. Mcneill, Scott Tanner

SC Upstate Research Symposium

Inflammatory bowel disease (IBD) is an autoimmune disease of unknown cause and includes conditions such as Crohn’s disease and ulcerative colitis. With no cure and only palliative therapies available, many patients with these conditions struggle with diarrhea, abdominal pain, and other chronic symptoms. This study is interested in investigating the multidrug resistance gene (MDR) which encodes the small molecule pump P-glycoprotein (P-gp).

This gene is responsible for regulating drug absorption and accumulation in various parts of the body such as the intestines which is of particular interest to this study. Polymorphisms of the MDR1 gene (encoding p-glycoprotein) have consequently been …

Mc-01 Identification Of Genes In Blastocoel Fluid Associated With Successful Ivf Outcomes Of Women Of Advanced Maternal Age, Hannah C. Archer, Thao Nguyen, Carson Collins, Kayla Vaillant, Molly Riehs, Sarayu Bethi, Renee J. Chosed

SC Upstate Research Symposium

Introduction: A patient may seek the use of IVF technology when they are struggling to become pregnant. To improve IVF outcomes, much research is focused on identifying markers to allow embryologists to transfer embryos with the greatest chance of a successful pregnancy. Women of advanced maternal age, which is thirty-five years and older have a lower chance of success on a first attempt with IVF, women at the age of 40 have a 9% chance of a live birth with IVF. Therefore, identification of an additional biomarker during preimplantation embryo development that is associated with successful implantation in AMA patients, …