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Full-Text Articles in Cell and Developmental Biology
Identification Of Size And Shape Changes In Orofacial Development And Disease, Allyson E. Kennedy
Identification Of Size And Shape Changes In Orofacial Development And Disease, Allyson E. Kennedy
Theses and Dissertations
Among the most prevalent and devastating types of human birth defects are those affecting the mouth and face, such as orofacial clefts. Children with malformed orofacial structures undergo multiple surgeries throughout their lifetime and struggle with facial disfigurements, speech, hearing, and eating problems. Therefore, facilitating new research in cranio- and orofacial development is paramount to prevention and treatment of these types of birth defects in humans. Xenopus laevis has emerged as a new tool for dissecting the mechanisms governing facial development. Thus, molecular analyses accompanied by quantitative assessment of morphological changes during orofacial development of this species could be very …