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Cell and Developmental Biology Commons™
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Full-Text Articles in Cell and Developmental Biology
Repressive Interactions Between Transcription Factors Separate Different Embryonic Ectodermal Domains., Steven L. Klein, Andre L P Tavares, Meredith Peterson, Charles H Sullivan, Sally A. Moody
Repressive Interactions Between Transcription Factors Separate Different Embryonic Ectodermal Domains., Steven L. Klein, Andre L P Tavares, Meredith Peterson, Charles H Sullivan, Sally A. Moody
Anatomy and Regenerative Biology Faculty Publications
The embryonic ectoderm is composed of four domains: neural plate, neural crest, pre-placodal region (PPR) and epidermis. Their formation is initiated during early gastrulation by dorsal-ventral and anterior-posterior gradients of signaling factors that first divide the embryonic ectoderm into neural and non-neural domains. Next, the neural crest and PPR domains arise, either