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Articles 1 - 17 of 17

Full-Text Articles in Biotechnology

Biomechanics Of Mantis Prey Capture, Danielle S. Taylor Jan 2023

Biomechanics Of Mantis Prey Capture, Danielle S. Taylor

Honors Theses

Mantis species have a variety of different morphologies, so do the extreme forms of mantis limbs trade prey catching capability for camouflage? We hypothesize that some extreme forms of mantis limbs that are associated with cryptic species may be associated with a tradeoff of the capability of those limbs. Previous research has developed 2D morphologies of several hundred species of mantises. We are creating a 3D morphology by using micro dissection, micro CT imaging to construct our 3D biomechanical model. We found the attachment points of the ligaments and muscles from a Tenodera forearm and have constructed a 2D biomechanical …


My Summer Working With Two-Spotted Spider Mites, Renée A. Smith Aug 2022

My Summer Working With Two-Spotted Spider Mites, Renée A. Smith

Undergraduate Student Research Internships Conference

Two-spotted spider mites are a polyphagous pest, capable of eating a magnitude of food crops which causes a large problem for Canadian agriculture. Their ability to consume various crops stems from their ability to adapt to various chemical defence mechanisms. This ability allows them to acquire resistance to many commonly used pesticides. This has resulted in large infections in Canadian farms with few options to prevent the pests from affecting crop yields. Take a look at my project if you'd like to see how the Grbic lab is working to combat this issue using genetic engineering techniques!


The Role Of Foxd1 In Clear Cell Renal Cell Carcinoma, Kyle H. Bond May 2022

The Role Of Foxd1 In Clear Cell Renal Cell Carcinoma, Kyle H. Bond

Electronic Theses and Dissertations

Renal cell carcinoma (RCC) is the 8th most common cancer in the United States, with the clear cell variant (ccRCC) being the most prevalent. Over 14,000 people die every year to RCC, with rates continuing to increase with an aging general population. Patients suffering from metastatic RCC (mRCC) have extremely poor prognoses, with a 5-year survival of only 11.2%. Current treatment options include resection of primary lesions, tyrosine kinase inhibition (Sunitinib, Pazopanib), mTOR inhibition (Temsirolimus, Everolimus), and immune checkpoint inhibition (Nivolumab, Atezolizumab). Recent attention has been drawn to inhibition of transcription factors like HIF2α (Belzutifan). There is a need …


Students Interest And Thoughts On Stem, Chrisitine Girtain Apr 2022

Students Interest And Thoughts On Stem, Chrisitine Girtain

STEM Month

I am Juan Sebastian Bohorquez Mora, I am a sophomore student at Toms River High School North. I am interested in biofuels because I believe they are a good option to replace fossil fuels. I am also interested in duckweed because biofuels are made out of crops, and people need to eat those crops. That’s when duckweed comes in and it can be used as a feedstock for ethanol production which is a biofuel. Bioethanol is a type of biofuel and it is derived from the corn’s starch. Instead of making ethanol from the corn’s starch, we can use duckweed …


Cpf1-Based Crispr Genome Editing In The Cyanobacterium N. Punctiforme, Soohan Woo Jan 2022

Cpf1-Based Crispr Genome Editing In The Cyanobacterium N. Punctiforme, Soohan Woo

University of the Pacific Theses and Dissertations

CRISPR systems have been growing in their utility and their application throughout the biological field as researchers continue to grow in their understanding of the relatively novel genome editing technology. However, despite the potential of CRISPR as a genome editing tool, the complexity of applying this technology to a specific organism calls for custom modifications to the system to improve its success rate. In this project, a CRISPR-Cpf1 system that can be effectively employed in the cyanobacterium Nostoc punctiforme was designed, with a focus on the hormogonium development of this species. Multiple plasmids containing the CRISPR system and targeting different …


The Classification Of Basket Neural Cells In The Mammalian Neocortex, Sreya Pudi Oct 2021

The Classification Of Basket Neural Cells In The Mammalian Neocortex, Sreya Pudi

Senior Theses

Basket neuronal cells of the mammalian neocortex have been classically categorized into two or more groups. Originally, it was thought that the large and small types are the naturally occurring groups that emerge from reasons that relate to neurobiological function and anatomical position. Later, a study based on anatomical and physiological features of these neurons introduced a third type, the net basket cell which is intermediate in size as compared to the large and small types. In this study, multivariate analysis was used to test the hypothesis that the large and small types are morphologically distinct groups. The results of …


Consistency Is Futile!: Selecting Phycoremediators For Consortia, Tori Spencer Apr 2019

Consistency Is Futile!: Selecting Phycoremediators For Consortia, Tori Spencer

BIO 410 Spring 2019 Research Papers

Bioremediation is the process by which organisms remove and transform toxic compounds in a contaminated source. This is a waste management technique currently used to clean up man-made contamination. Many organisms act as natural remediators; in the case of algae, they are called phycoremediators who perform phycoremediaton. The term algae encompasses a variety of taxonomic groups and their diversity is still being realized; there are over 44,000 named species of the 72,000 species that we have identified. Some estimates calculate that there are over 200,000 diatom species alone. This diversity continues to be difficult to organize, which is problematic for …


Histology For Cytotechnologists I, Joanna Burkhardt Jan 2019

Histology For Cytotechnologists I, Joanna Burkhardt

Library Impact Statements

No abstract provided.


Cytology Practicum Iii Mls 567, Joanna Burkhardt Jan 2019

Cytology Practicum Iii Mls 567, Joanna Burkhardt

Library Impact Statements

No abstract provided.


Histology For Cytotechnologists Ii Mls 568, Joanna Burkhardt Jan 2019

Histology For Cytotechnologists Ii Mls 568, Joanna Burkhardt

Library Impact Statements

No abstract provided.


Investigation On The Effect Of Pasteurisation On The Bacteria Contamination Of Eggs, Alya Sufiyah Bte Mohamed Subhan Jun 2018

Investigation On The Effect Of Pasteurisation On The Bacteria Contamination Of Eggs, Alya Sufiyah Bte Mohamed Subhan

The International Student Science Fair 2018

This project is a research on bacteria contamination on pasteurised and non-pasteurised eggs. In Singapore, there has been an increase in salmonella cases since 2016. Recently in the US, more than 206 million eggs in supermarkets and grocery chains had to be recalled. This project will explain about the different in bacterial colonies found on seemingly similar eggs.


Optimization Of A Genomic Editing System Using Crispr/Cas9-Induced Site-Specific Gene Integration, Jillian L. Mccool Ms., Nick Hum, Gabriela G. Loots Aug 2016

Optimization Of A Genomic Editing System Using Crispr/Cas9-Induced Site-Specific Gene Integration, Jillian L. Mccool Ms., Nick Hum, Gabriela G. Loots

STAR Program Research Presentations

The CRISPR-Cas system is an adaptive immune system found in bacteria which helps protect against the invasion of other microorganisms. This system induces double stranded breaks at precise genomic loci (1) in which repairs are initiated and insertions of a target are completed in the process. This mechanism can be used in eukaryotic cells in combination with sgRNAs (1) as a tool for genome editing. By using this CRISPR-Cas system, in addition to the “safe harbor locus,” ROSAβ26, the incorporation of a target gene into a site that is not susceptible to gene silencing effects can be achieved through few …


Draft Genome Sequences Of Six Different Staphylococcus Epidermidis Clones, Isolated Individually From Preterm Neonates Presenting With Sepsis At Edinburgh's Royal Infirmary, Paul Walsh, M. Bekaert, J. Carroll, T. Manning, B. Kelly, A. O'Driscoll, X. Lu, C. Smith, P. Dickinson, K. Templeton, P. Ghazal, Roy D. Sleator May 2015

Draft Genome Sequences Of Six Different Staphylococcus Epidermidis Clones, Isolated Individually From Preterm Neonates Presenting With Sepsis At Edinburgh's Royal Infirmary, Paul Walsh, M. Bekaert, J. Carroll, T. Manning, B. Kelly, A. O'Driscoll, X. Lu, C. Smith, P. Dickinson, K. Templeton, P. Ghazal, Roy D. Sleator

Department of Biological Sciences Publications

Herein, we report the draft genome sequences of six individual Staphylococcus epidermidis clones, cultivated from blood taken from different preterm neonatal sepsis patients at the Royal Infirmary, Edinburgh, Scotland, United Kingdom.


Genome Wide Association Mapping Of Grain Arsenic, Copper, Molybdenum And Zinc In Rice (Oryza Sativa L.) Grown At Four International Field Sites, Gareth J. Norton, Alex Douglas, Brett Lahner, Elena Yakubova, Mary Lou Guerinot, Shannon R.M Pinson, Lee Tarpley, George C. Eizenga, Steve P. Mcgrath, Fang-Jie Zhao Feb 2014

Genome Wide Association Mapping Of Grain Arsenic, Copper, Molybdenum And Zinc In Rice (Oryza Sativa L.) Grown At Four International Field Sites, Gareth J. Norton, Alex Douglas, Brett Lahner, Elena Yakubova, Mary Lou Guerinot, Shannon R.M Pinson, Lee Tarpley, George C. Eizenga, Steve P. Mcgrath, Fang-Jie Zhao

Dartmouth Scholarship

The mineral concentrations in cereals are important for human health, especially for individuals who consume a cereal subsistence diet. A number of elements, such as zinc, are required within the diet, while some elements are toxic to humans, for example arsenic. In this study we carry out genome-wide association (GWA) mapping of grain concentrations of arsenic, copper, molybdenum and zinc in brown rice using an established rice diversity panel of ~300 accessions and 36.9 k single nucleotide polymorphisms (SNPs). The study was performed across five environments: one field site in Bangladesh, one in China and two in the US, with …


A Tale Of Two Investigations In Molecular Biology: The Use Of Pcr Technology To Identify Bacteria Containing Genes For Pha Synthesis And The Antibiotic Sensitivity Profile Of Vibrio Species B-18, Diana B. Lizarazo Jan 2008

A Tale Of Two Investigations In Molecular Biology: The Use Of Pcr Technology To Identify Bacteria Containing Genes For Pha Synthesis And The Antibiotic Sensitivity Profile Of Vibrio Species B-18, Diana B. Lizarazo

Honors Projects

The Vibrio species, B-18, produces PHA, a bacterial storage material with application as a biodegradable plastic. Phase one of this project aimed at determining if PCR technology could be used to find other bacteria that produce a similar type of PHA. Results showed that the primer sets utilized were not able to identify bacteria with PHA genes. Phase two hoped to discover if it would be possible to introduce Escherichia coli plasmids into B-18 using electroporation. Results demonstrated that electroporation was not useful for introducing plasmids into B-18.


In Vitro Expression And Purification Of Class I Mhc Molecules, Loi Cheng May 2006

In Vitro Expression And Purification Of Class I Mhc Molecules, Loi Cheng

Honors Scholar Theses

The major histocompatibility complex (MHC) is a gene family responsible for many critical functions of the immune system in most vertebrates. The MHC consists of three classes differentiated by their structure and function, and MHC class I encodes antigen binding proteins as well as chaperone and accessory proteins such as tapasin. The purpose of this project is to reconstitute several human MHC class I molecules in their peptide-filled and peptide-deficient forms, and to purify these proteins for biochemical study. The expressed proteins include wild type and mutant variants of the fusion protein human leukocyte antigen HLA-B*0801-fos, and human beta-2-microglobulin (β2m). …


Taxonomy And Biology Of A New Oecophoridae (Lepidoptera) From Central Chile, T. Heath Ogden Dec 2000

Taxonomy And Biology Of A New Oecophoridae (Lepidoptera) From Central Chile, T. Heath Ogden

T. Heath Ogden

The adult, larva, and pupa of Afdera jimenae Ogden & Parra sp. nov. are described and illustrated. Larvae live in leaf litter throughout all instars and are generalists feeding upon the fallen leaves of a number of different plant species of sclerophyllous forests. Comments on morphological details and bionomics of this species are given. This is the second species of Afdera know for Chile.