Open Access. Powered by Scholars. Published by Universities.®
- Institution
-
- University of Dayton (105)
- Alayen Iraqi University (65)
- City University of New York (CUNY) (18)
- University of South Carolina (18)
- United Arab Emirates University (17)
-
- American University in Cairo (16)
- Munster Technological University (16)
- Eastern Illinois University (15)
- California Polytechnic State University, San Luis Obispo (13)
- Stephen F. Austin State University (11)
- Syracuse University (6)
- Technological University Dublin (6)
- University of Kentucky (6)
- University of Texas Rio Grande Valley (6)
- Karbala International Journal of Modern Science (5)
- Western Kentucky University (5)
- LSU New Orleans (4)
- The Texas Medical Center Library (4)
- University of Louisville (4)
- Aga Khan University (3)
- Augustana College (3)
- Cal Poly Humboldt (3)
- Calvin University (3)
- Claremont Colleges (3)
- Howard University (3)
- Kennesaw State University (3)
- Liberty University (3)
- Texas Southern University (3)
- University of Denver (3)
- University of the Pacific (3)
- Keyword
-
- Data representation (14)
- Robert Hooke (14)
- Scientific imaging (14)
- Microbiology (13)
- Biology (12)
-
- 1.6 BIOLOGICAL SCIENCES (10)
- 3.3 HEALTH SCIENCES (6)
- 3.4 HEALTH BIOTECHNOLOGY (6)
- Biochemistry and molecular biology (6)
- Bioinformatics (6)
- Pseudomonas aeruginosa (6)
- Technologies involving identifying the functioning of DNA, (6)
- Carbapenemase (5)
- Cellulose (5)
- Infectious diseases (5)
- MRSA (5)
- Neurodegeneration (5)
- Protein (5)
- 3. MEDICAL AND HEALTH SCIENCES (4)
- ACC deaminase (4)
- Algae (4)
- Arabidopsis (4)
- Biotechnology (4)
- Cloning (4)
- Dormancy (4)
- Ethylene (4)
- Gene regulation (4)
- Genetic engineering (4)
- Genetics (4)
- Hybrid poplar (4)
- Publication Year
- Publication
-
- Biology Faculty Publications (109)
- AUIQ Complementary Biological System (65)
- Faculty Research & Creative Activity (15)
- Archived Theses and Dissertations (14)
- Department of Biological Sciences Publications (12)
-
- Faculty Publications (12)
- Publications and Research (11)
- Theses (10)
- Biology Theses (9)
- STAR Program Research Presentations (8)
- Renée Crown University Honors Thesis Projects - All (6)
- Section 1: Introduction (6)
- Theses and Dissertations (6)
- Articles (5)
- Electronic Theses and Dissertations (5)
- Karbala International Journal of Modern Science (5)
- Section 4: Imaging the Concealed (5)
- LSU New Orleans Theses and Dissertations (4)
- Section 2: Imaging the Microscopic (4)
- Cal Poly Humboldt theses and projects (3)
- Department of Biology Faculty Publications (3)
- Dissertations and Theses (Open Access) (3)
- Dissertations, Theses, and Capstone Projects (3)
- Journal Articles (3)
- Master's Theses (3)
- Publications (3)
- Research Symposium (3)
- Summer Research (3)
- Theses & Dissertations (3)
- Theses and Dissertations--Pharmacy (3)
- Publication Type
- File Type
Articles 31 - 60 of 472
Full-Text Articles in Biotechnology
Identifying Controls On The Biodegradation Of Dissolved Organic Matter To Inform Microbial Fuel Cell Applications, Lily N. O'Hagan
Identifying Controls On The Biodegradation Of Dissolved Organic Matter To Inform Microbial Fuel Cell Applications, Lily N. O'Hagan
Dissertations, Master's Theses and Master's Reports
Microbial fuel cells (MFCs) harness dissolved organic matter (DOM) biodegradation to generate power. To evaluate effects of DOM source, nutrients (nitrate and phosphate), and oxygen on DOM biodegradation, we conducted 4-day DOM biodegradation experiments with water and sediments from the Chesapeake Bay. Compared to soil-derived DOM, algal-derived DOM composition changed more and nearly doubled carbon dioxide (CO2) production, peak CO2 rates, and carbon removal, indicating MFC site selection should target regions with algal-rich DOM. Aerobic conditions increased CO2 production by ca. 16%, doubled peak CO2 rates, and reached peak rates 1 hour faster than anaerobic …
Neuroprotective Effects Of Aqueous Extract Of Bryophyllum Pinnatum Against Lead Acetate Induced Damage In The Cerebellum Of Rats, O. A. Bamgbose, O. D. Akanji, E. O. Olayemi, D. O. Taiwo-Ola, K. O. Odubela, B. A. Akanbi, P. B. Fakunle
Neuroprotective Effects Of Aqueous Extract Of Bryophyllum Pinnatum Against Lead Acetate Induced Damage In The Cerebellum Of Rats, O. A. Bamgbose, O. D. Akanji, E. O. Olayemi, D. O. Taiwo-Ola, K. O. Odubela, B. A. Akanbi, P. B. Fakunle
AUIQ Complementary Biological System
Lead is a persistent environmental toxin with pronounced neurotoxic effects, particularly on the central nervous system. This study evaluated the impact of lead acetate on the cerebellar cortex of adult Wistar rats and assessed the neuroprotective effects of aqueous Bryophyllum pinnatum extract. Twenty adult Wistar rats (180–220 g) were randomly assigned to four groups (n = 5): Control (distilled water), T1 (0.075 mg/kg lead acetate), T2 (100 mg/kg B. pinnatum), and T3 (lead + B. pinnatum). Treatments were administered orally for 21 days. Cerebellar tissues were processed for biochemical and histological analysis, and data were analyzed using GraphPad Prism v10.1.Lead …
Cytological Changes In Buccal Mucosa Among Yemeni Qat Chewers In Hadhramout Governorate: A Comparative Cross-Sectional Study, Saleh H. Ben Sumaidea, Hassan Pyar, Abdullah O. Bin Nashwan, Abdullah M. Bin Fadhl, Abeer A. Marabi, Ahmed A. Al-Shetri, Gumaan S. Rassam, Halima K. Joher, Mashhoor A. Bin Shehab, Mohammed S. Bin Mosalem
Cytological Changes In Buccal Mucosa Among Yemeni Qat Chewers In Hadhramout Governorate: A Comparative Cross-Sectional Study, Saleh H. Ben Sumaidea, Hassan Pyar, Abdullah O. Bin Nashwan, Abdullah M. Bin Fadhl, Abeer A. Marabi, Ahmed A. Al-Shetri, Gumaan S. Rassam, Halima K. Joher, Mashhoor A. Bin Shehab, Mohammed S. Bin Mosalem
AUIQ Complementary Biological System
Qat (Catha edulis) chewing is a common practice in Yemen, associated with oral mucosal irritation. The objective of the current study is to compare cytological findings of buccal mucosa between Qat chewers and non-chewers. A comparative cross-sectional study was designed. Buccal smears were collected from chewers (n = 100) and non-chewers (n = 100), fixed, and stained with Harris hematoxylin staining. Smears were assessed for inflammatory changes and cytological atypia by two blinded examiners; disagreements were resolved by consensus. The inflammatory cells were observed in 21% of chewers compared to 8% of controls (P = 0.009), while …
The Role Of Human Alpha Defensin 5 (Hd5) In Disrupted Wound Healing Processes In Crohn’S Colitis, Jafer Aljorani, Amanda Williams
The Role Of Human Alpha Defensin 5 (Hd5) In Disrupted Wound Healing Processes In Crohn’S Colitis, Jafer Aljorani, Amanda Williams
Student Scholar Symposium
Wound healing is a complex biological process requiring the coordinated function of multiple proteins. In chronic inflammatory bowel disease (IBD), particularly Crohn’s Colitis (CC), this process is dysregulated, leading to delayed tissue repair and increased disease burden. Prior studies indicate that Human Alpha Defensin 5 (HD5) is over-expressed in the colonic epithelium of CC patients, yet its impact on wound healing remains poorly understood. Our laboratory has identified that HD5 may impair wound healing by modulating key structural and regulatory proteins. Preliminary findings suggest that HD5 reduces the expression and function of desmoplakin, a critical desmosomal protein essential for maintaining …
Protocols For Antioxidant Testing: A Mini Review Of Common Assays And Approaches, Abdulsalam Halboup, Sameer A. Alkubati
Protocols For Antioxidant Testing: A Mini Review Of Common Assays And Approaches, Abdulsalam Halboup, Sameer A. Alkubati
AUIQ Complementary Biological System
Antioxidants play a pivotal role in mitigating damage caused by oxidative stress, which is implicated in aging, inflammation, neurodegeneration, and various chronic diseases. With the growing interest in natural and synthetic antioxidants across nutraceutical, pharmaceutical, and food industries, the need for reliable, reproducible, and standardized testing methods has become increasingly urgent. This mini-review provides a structured overview of the most widely used antioxidant testing protocols, categorized into in vitro chemical-based assays (e.g., DPPH, ABTS, FRAP, metal chelation), cell-based assays (e.g., DCFH-DA for intracellular ROS detection), and in vivo biomarker-based models. Each method’s principle, experimental protocol, advantages, and limitations are critically …
Prevalence Of Giardia Infection: A Cross-Sectional Study In Basra Province, Iraq, Sarah Kamal Naser
Prevalence Of Giardia Infection: A Cross-Sectional Study In Basra Province, Iraq, Sarah Kamal Naser
AUIQ Complementary Biological System
Giardiasis is a common parasite infection that is seen more frequently than any other parasitic infection worldwide. This infection is especially prevalent in tropical areas and in developing nations that have a poor standard of living and poor health conditions. The Giardia parasite is able to infect people of any gender, as it enters the body by the mouth, passes down the oesophagus, and finally reaches the stomach, where it is not negatively impacted by gastric acids. The goal of this study is to determine the extent to which patients who were treated at Al-Zubair General Hospital in Basra, Iraq, …
Synthesis Of Antibody Functionalized Polyaniline/Polystyrene/N-Gqds Composite Fibermats For Sweat Based Cortisol Biosensing Applications, Ashwin James
Honors Theses
Noninvasive, wearable biosensors capable of detecting stress biomarkers in sweat require electrodes that are flexible, conductive, insoluble in water, and highly sensitive at low concentrations of analyte. In this work, bovine serum albumin blocked and anti-cmab immobilized nitrogen doped graphene quantum dots integrated polyaniline/polystyrene composite fibermat electrodes (BSA/Anti-Cmab/N-GQDs/PANI/PS electrodes) were synthesized and evaluated as a potential platform for an electrochemical cortisol biosensor in sweat based systems. Polyaniline was utilized in order to provide electrical conductivity, while polystyrene served as a carrying polymer for mechanical support and its hydrophobicity. Composite fibermats were manufactured through Forcespinning™, followed by a secondary polyaniline graft …
Mmp-7 Expression And Rs11225307 Polymorphism In Breast Cancer And Fibroadenoma: A Molecular Study In Basrah, Iraq, Heba Jassam, Wijdan Nazar Ibraheim, Mazin Hawwaz Abdulridha, Rafid Adil Abood, Karam B. Nanjem
Mmp-7 Expression And Rs11225307 Polymorphism In Breast Cancer And Fibroadenoma: A Molecular Study In Basrah, Iraq, Heba Jassam, Wijdan Nazar Ibraheim, Mazin Hawwaz Abdulridha, Rafid Adil Abood, Karam B. Nanjem
AUIQ Complementary Biological System
Breast cancer (BC) progression relies heavily on extracellular matrix degradation, mediated in part by matrix metalloproteinase-7 (MMP-7). While overexpression of MMP-7 has been implicated in multiple cancers, data from Middle Eastern populations remain limited.
This study examined MMP-7 gene expression and polymorphism patterns, with emphasis on rs11225307, in breast cancer versus benign fibroadenoma (FA) tissues among women in Basrah, Iraq. Thirty-seven BC and twenty-three FA patients were enrolled. MMP-7 mRNA expression was quantified using qRT-PCR and normalized to β-actin, while polymorphisms were analyzed through Sanger sequencing of eight SNPs and allele-specific PCR for rs11225307. Statistical significance was set at …
Screening For Potential Plant Growth‐Promoting Rhizobacteria (Pgpr)-Assisted Phytoremediation To Mitigate Lead Toxicity In Uae Soils, Zeinab Mohamed Abdalla
Screening For Potential Plant Growth‐Promoting Rhizobacteria (Pgpr)-Assisted Phytoremediation To Mitigate Lead Toxicity In Uae Soils, Zeinab Mohamed Abdalla
Theses
This study investigates the potential of lead (Pb)-tolerant actinobacteria that possess 1-aminocyclopropane-1-carboxylate deaminase (ACCD) activity and plant growth-promoting (PGP) traits to serve as a biological tool for enhancing the growth of corn (Zea mays L.) under Pb stress. The primary objective of this research was to isolate and characterize novel, Pb-tolerant, rhizosphere-competent actinobacteria and to evaluate their efficacy in mitigating Pb toxicity, reducing its uptake, and promoting biomass accumulation in corn grown in contaminated soil. A total of 43 actinobacterial isolates were obtained from Pb-contaminated rhizosphere soil and screened for Pb tolerance, rhizosphere competence, ACCD activity, and PGP traits. …
Comparison Of Metal Nanoparticles As Antifungal Agents: Efficacy, Mechanisms, And Toxicity Against Candida, Aspergillus, And Cryptococcus, Ahmed Falah Imran, Hayder Hameed Saeed, Khaldoon Jasim Mohammed
Comparison Of Metal Nanoparticles As Antifungal Agents: Efficacy, Mechanisms, And Toxicity Against Candida, Aspergillus, And Cryptococcus, Ahmed Falah Imran, Hayder Hameed Saeed, Khaldoon Jasim Mohammed
AUIQ Complementary Biological System
Candida albicans, Aspergillus fumigatus, and Cryptococcus neoformans are the invasive fungi whose diseases are becoming a growing health issue in the global community, particularly in immunocompromised people. The increasing resistance of the conventional antifungals and the shortage of the existing treatment methods require alternative methods. The present review is an evaluation of the antifungal activity of metal-based nanoparticles, including silver (Ag), copper (Cu), zinc oxide (ZnO), titanium dioxide (TiO2), and selenium (Se) in relation to the three predominant pathogenic fungi. It also talks about their mode of action, relative efficacy, toxicity and their possible future clinical …
Renoprotective Potential Of Ciprofloxacin, Prednisolone, And Infliximab In Acetic Acid-Induced Ulcerative Colitis Rats, O. A. Oyesola, O. E. Olayemi, B. I. Kukoyi
Renoprotective Potential Of Ciprofloxacin, Prednisolone, And Infliximab In Acetic Acid-Induced Ulcerative Colitis Rats, O. A. Oyesola, O. E. Olayemi, B. I. Kukoyi
AUIQ Complementary Biological System
Ulcerative colitis (UC) is a chronic inflammatory bowel disease with systemic manifestations, including renal impairment mediated by oxidative stress, inflammation, and electrolyte imbalance. This study investigated the renoprotective potential of ciprofloxacin, prednisolone, and infliximab in rats with acetic acid–induced UC. Fifty male Sprague–Dawley rats (180–200 g) were divided into five groups (n = 10): control, UC control, UC + ciprofloxacin (50 mg/kg, p.o.), UC + prednisolone (4 mg/kg, p.o.), and UC + infliximab (5 mg/kg, i.p.). UC was induced by rectal instillation of 4% acetic acid, and treatments were administered for 42 days. Serum urea, creatinine, electrolytes, and malondialdehyde (MDA) …
Mesenchymal Stem Cells As Cornerstones Of Regenerative Medicine: Mechanisms, Applications, And Future Perspectives, Hasan M. Agha, Mohammed A. Abdalqader, Jantson Hoh, Yacoub Wassouf, Khudhur Abbas Ahmed Al-Saadawi, Amjad Abdulhadi Mohammed, Muneer Mohammed Saleh Alsayadi
Mesenchymal Stem Cells As Cornerstones Of Regenerative Medicine: Mechanisms, Applications, And Future Perspectives, Hasan M. Agha, Mohammed A. Abdalqader, Jantson Hoh, Yacoub Wassouf, Khudhur Abbas Ahmed Al-Saadawi, Amjad Abdulhadi Mohammed, Muneer Mohammed Saleh Alsayadi
AUIQ Complementary Biological System
Regenerative medicine is a multidisciplinary domain focused on restoring, repairing, or replacing damaged tissues and organs by harnessing the body’s inherent healing abilities with sophisticated biological and technical techniques. Mesenchymal stem cells (MSCs) have become fundamental among many stem cell types because to their self-renewal, multipotency, paracrine signaling, and immunomodulatory capabilities. Their therapeutic adaptability has been shown in orthopedic, cardiovascular, neurological, dermatological, and immune-mediated illnesses, underscoring their clinical significance. Nonetheless, obstacles like donor heterogeneity, senescence during in vitro growth, restricted engraftment, and regulatory impediments persist in limiting repeatability and broad clinical use. Recent advancements are enhancing the capabilities of MSCs …
Evaluating The Pros And Cons Of Common Dental Polymers In Dentistry: Review, Ali Kadhim Wadday, Sukaina Tuama Ghafel, Lina M. Shaker
Evaluating The Pros And Cons Of Common Dental Polymers In Dentistry: Review, Ali Kadhim Wadday, Sukaina Tuama Ghafel, Lina M. Shaker
AUIQ Complementary Biological System
Dental polymers play a central role in modern dentistry, offering versatility in applications ranging from removable dentures and prosthetic frameworks to implant abutments and bioactive scaffolds. Common materials like PMMA, PEEK, and nylon are valued for their formability, cost-effectiveness, and aesthetic properties, while emerging biopolymers including chitosan and alginate offer promising biocompatible alternatives. However, both conventional and bio-based polymers exhibit limitations in terms of chemical stability, mechanical wear, and microbial adhesion. Recent advancements in polymer science have expanded the material palette through innovative biopolymer formulations and advanced surface engineering techniques such as antimicrobial coatings and nanocomposites, introducing novel solutions for …
Efficacy Of Pethidine And Tramadol In The Suppression Of Postoperative Shivering: A Comparative Study, Ahmed Jaber Ibrahim, Hussien Ibrahim Hayal, Ahmed R.Y. Al-Sawad, Shahab Abdulla, Ralela Makline
Efficacy Of Pethidine And Tramadol In The Suppression Of Postoperative Shivering: A Comparative Study, Ahmed Jaber Ibrahim, Hussien Ibrahim Hayal, Ahmed R.Y. Al-Sawad, Shahab Abdulla, Ralela Makline
AUIQ Complementary Biological System
Postoperative shivering is a common complication that can affect patient comfort and stability. Pethidine and tramadol are widely used to relieve this symptom, but their relative effectiveness and safety remain under investigation. In this randomized trial, 50 patients (aged 25–35 years) with postoperative shivering were divided into two groups: one group receiving intravenous tramadol (n = 25 patients) and one group receiving pethidine (n = 25 patients). Onset of drug action, vital signs, and side effects were systematically assessed. Pethidine had a significantly faster onset of action than tramadol (12.20 ± 0.35 min vs 7.16 ± 0.28 min, p < 0.001). No significant differences were observed between the two groups regarding body temperature, heart rate, oxygen saturation, or blood pressure (P < 0.05). Side effects, such as dizziness (16% vs. 8%), nausea and vomiting (20% vs. 8%), and nausea alone (48% vs. 20%), were more common and showed a statistically significant increase in the tramadol group. Both drugs were effective in suppressing postoperative tremor, but pethidine demonstrated superior efficacy, a faster onset of action, and a better safety profile. These results confirm pethidine as the recommended choice at an intravenous dose of 0.5 mg/kg.
The Physiological Impacts Of Nano-Ceramic Window Films In Hot-Climate Architecture: Theoretical Biological Study, Lina M. Shaker, Shahab Abdulla, Ralela Makline
The Physiological Impacts Of Nano-Ceramic Window Films In Hot-Climate Architecture: Theoretical Biological Study, Lina M. Shaker, Shahab Abdulla, Ralela Makline
AUIQ Complementary Biological System
This research explores the integration of nano-ceramic window films as a passive architectural strategy to improve both energy performance and occupant biological well-being in commercial buildings. The biological objective centers on enhancing health, comfort, and physiological stability by regulating thermal, optical, and radiative indoor conditions. Simulations on a three-story, 2,000 m² building demonstrated that high-performance films reduced indoor temperatures by up to 3.5°C, lowering thermal stress and core body heat load. Ultraviolet (UV) transmission was curtailed to as low as 1%, significantly decreasing skin damage doses below 0.2 MED/day. Select films maintained optimal Equivalent Melanopic Lux (EML) levels (up to …
The Best Cut: Evaluating Block, Sliced, And Diced Cartilage In Dorsal Augmentation Rhinoplasty, Trimartani Koento, Mirta Hediyati Reksodiputro, Mikhael Yosia
The Best Cut: Evaluating Block, Sliced, And Diced Cartilage In Dorsal Augmentation Rhinoplasty, Trimartani Koento, Mirta Hediyati Reksodiputro, Mikhael Yosia
AUIQ Complementary Biological System
Rhinoplasty is a surgical procedure aimed at improving the nasal shape and function, with dorsal augmentation playing a crucial role in nasal reconstruction. Autologous cartilage grafts, particularly from the rib, are widely used due to their structural integrity but pose challenges such as postoperative warping, graft shifting, and resorption. The evolution of cartilage grafting techniques has progressed from block to sliced and diced cartilage to enhance long-term stability and aesthetic outcomes. Block cartilage provides excellent structural support but is prone to warping due to intrinsic stress. Sliced cartilage reduces warping risk while offering greater flexibility, whereas diced cartilage allows for …
Antibiogram Development For Neonatal Intensive Care Unit In A Referral Hospital In Sana'a City, Yemen, Mohammed A. Kubas, Massoud K. Rassam, Amaal A. Alsayani
Antibiogram Development For Neonatal Intensive Care Unit In A Referral Hospital In Sana'a City, Yemen, Mohammed A. Kubas, Massoud K. Rassam, Amaal A. Alsayani
AUIQ Complementary Biological System
Neonates have an immature immune system, making them highly susceptible to infections. Treatment failure in newborns may result from antibiotic resistance, a significant challenge in the management of infectious illnesses worldwide. So the main objective of this research was to develop a newborn-specific antibiogram at the University of Science and Technology hospital (USTH) in Sana’a, Yemen. A retrospective analysis was conducted using microbiological data from the USTH database during the period from January 2021 to March 2022, antibiogram was generated and analyzed using the WHONET application. Gram-positive bacteria were the most frequently isolated pathogens in neonates, followed by gram-negative bacteria. …
Biosorption Of Crystal Violet Onto Fenugreek Seed Powder: Comprehensive Optimization Through Response Surface Methodology And Elucidation Of Dye Uptake Mechanism, Hasan M. Agha, Zaher Mundher Yaseen, Wafaa Raji Alfatlawi, Khansaa Al-Essa, Abdallah Reghioua, Hussein A. Kazem, Lee D. Wilson
Biosorption Of Crystal Violet Onto Fenugreek Seed Powder: Comprehensive Optimization Through Response Surface Methodology And Elucidation Of Dye Uptake Mechanism, Hasan M. Agha, Zaher Mundher Yaseen, Wafaa Raji Alfatlawi, Khansaa Al-Essa, Abdallah Reghioua, Hussein A. Kazem, Lee D. Wilson
AUIQ Complementary Biological System
This work investigates the efficacy of fenugreek seed powder (FSP), an agricultural product, as an economical and sustainable biosorbent for the extraction of crystal violet (CV) dye from aqueous environments. The biosorbent was analyzed using XRD, FTIR, and SEM-EDX, validating its amorphous structure, surface functional groups, and porous shape. Batch biosorption tests were adjusted utilizing a Box–Behnken design (BBD), incorporating three independent variables: FSP dose (0.02–0.1 g/100 mL), pH (4–10), and time (5–60 min). The model exhibited exceptional prediction accuracy (R² = 0.99, CV = 2.12%) and recognized all three variables as statistically significant (p < 0.05). The maximum CV removal attained was 91.8% efficiency at an FSP dose of 0.1 g/100 mL, pH 7, and a time of 60 minutes. FTIR examination indicated changes in the –OH, C=O, and C–O functional groups, signifying their participation in dye interaction, whilst SEM pictures validated dye deposition on the biosorbent surface. The biosorption process was ascribed to electrostatic forces, hydrogen bonding, π–π stacking, and pore filling. These findings underscore FSP as a viable, economical biosorbent for the removal of cationic dyes in wastewater treatment applications.
In Silico Investigation Of The Anticancer Activity Of Natural Isoquinoline Alkaloids Targeting The Monoamine Oxidase A Enzyme, Reham A. Al-Anssari, Anwar H. Ali, Ola Adel Al-Saad, Shaker A.N. Al-Jadaan
In Silico Investigation Of The Anticancer Activity Of Natural Isoquinoline Alkaloids Targeting The Monoamine Oxidase A Enzyme, Reham A. Al-Anssari, Anwar H. Ali, Ola Adel Al-Saad, Shaker A.N. Al-Jadaan
AUIQ Complementary Biological System
Monoamine oxidase A (MAO-A) has recently been identified as a candidate for cancer therapy due to its roles in tumor development and growth. Conventional approaches for the discovery of MAO-A inhibitors are both costly and time-consuming. The objective of this work was to apply in silico methods to predict natural isoquinoline alkaloids capable of acting as potent MAO-A inhibitors, and to establish this class of compounds as potential sources of a cost-effective anticancer therapy. Twenty-one natural isoquinoline alkaloids were subjected to a multistep computer-aided drug discovery protocol. The compounds were initially screened for pharmacokinetic (ADME), toxicity, and drug-likeliness properties by …
Applying Transcriptomics For Technology Development And Conservation In North American Marine Organisms, Cory Von Eiff
Applying Transcriptomics For Technology Development And Conservation In North American Marine Organisms, Cory Von Eiff
Dissertations
RNA biology is a rapidly expanding field, with many avenues of discovery among marine organisms. In this study, we analyze both mollusks and sawfish. First, we perform an evaluation of sRNA biogenesis pathways throughout Mollusca, with emphasis on the easter oyster, Crassostrea virginica. Understanding these molecules prescribes RNAi-based gene silencing approaches, benefiting genetic investigation and biotechnology. Similar to other animal groups, mollusks have conserved microRNAs (miRNAs), with some shared with ecdysozoans and deuterostomes; however, there is no evidence of an endogenous small interfering RNA (siRNA) pathway. These results suggest that long double-stranded RNA (dsRNA)-based RNAi is not appropriate for gene …
Reframing Sleep Diagnostics: A Structured Clinical Guide To Polysomnography Evaluation, Elvie Zulka Kautzia Rachmawati, Mikhael Yosia
Reframing Sleep Diagnostics: A Structured Clinical Guide To Polysomnography Evaluation, Elvie Zulka Kautzia Rachmawati, Mikhael Yosia
AUIQ Complementary Biological System
Polysomnography (PSG) remains the gold standard for evaluating sleep-disordered breathing (SDB) and related conditions, yet its clinical potential is often limited by overreliance on the apnea-hypopnea index (AHI) and similar summary metrics. This narrative review offers a structured, physiology-informed approach to PSG interpretation that integrates sleep architecture, arousal burden, respiratory event morphology, oxygenation patterns, and CO2 trends. Recognizing phenotypic patterns-such as REM-related and positional OSA-through sleep stage and positional stratification is essential for directing targeted therapy. We outline common interpretive pitfalls, including automated scoring errors, overlooked signal artifacts, and the first night effect, emphasizing the need for careful manual …
Transformative Role Of Laser Technology In Ophthalmology And Dermatology: A Mini Review Of Precision Applications In Modern Medicine, Haider Hameed, Maryam Aqeel, Hussein Rafid, Rasha Sabah, Mustafa Fadhel, Zahraa Hameed, Muqtada Khalawi, Zahraa Sarmed, Ail Ahmed, Ayat Abd Albari, Lina M. Shaker
Transformative Role Of Laser Technology In Ophthalmology And Dermatology: A Mini Review Of Precision Applications In Modern Medicine, Haider Hameed, Maryam Aqeel, Hussein Rafid, Rasha Sabah, Mustafa Fadhel, Zahraa Hameed, Muqtada Khalawi, Zahraa Sarmed, Ail Ahmed, Ayat Abd Albari, Lina M. Shaker
AUIQ Complementary Biological System
Laser technology has significantly transformed healthcare and biological sciences by Laser devices are offered precision, efficiency, and Multiple simple solutions in various medical fields and research domains. In ophthalmology, lasers play a pivotal role in vision correction, retinal imaging, and therapeutic applications, such as femtosecond laser-assisted LASIK and two-photon fluorescence scanning laser ophthalmoscopy. Dermatology has also benefited from CO2, Nd:YAG, excimer, and Q-switched lasers, which are widely used for pigmentation disorders, tattoo removal, and skin rejuvenation. Moreover, Low-Level Laser Therapy (LLLT) enhances wound healing and tissue regeneration, while intense pulsed light (IPL) and diode lasers improve hair removal …
The High Burden Of Depression, Anxiety, And Stress Among University Students In Southern Iraq: A Cross-Sectional Study, Hassan Al-Karagoly, Zahraa Al-Attar, Hjar Al-Asadi, Sajad Al-Lahibi, Russul Al-Fartousi, Teeba Al-Jadry, Menatallah Bali, Baneen Al-Hasnawi, Hanan Al-Aboudi, Zainab Al-Fadliu, Ali Al-Mosawi, Zahraa Al-Aboudi, Qassim Al-Rubaie, Mohsin Al-Samawi, Abdulsalam Halboup
The High Burden Of Depression, Anxiety, And Stress Among University Students In Southern Iraq: A Cross-Sectional Study, Hassan Al-Karagoly, Zahraa Al-Attar, Hjar Al-Asadi, Sajad Al-Lahibi, Russul Al-Fartousi, Teeba Al-Jadry, Menatallah Bali, Baneen Al-Hasnawi, Hanan Al-Aboudi, Zainab Al-Fadliu, Ali Al-Mosawi, Zahraa Al-Aboudi, Qassim Al-Rubaie, Mohsin Al-Samawi, Abdulsalam Halboup
AUIQ Complementary Biological System
University students often face significant academic, social, and environmental pressures, making them particularly vulnerable to psychological distress. Despite this, there is limited evidence regarding the prevalence and associated factors of mental health problems among university students in Iraq. Therefore, this study aimed to assess the prevalence and severity of depression, anxiety, and stress in this population and to examine their associations with sociodemographic characteristics, insomnia, internet use, and physical activity. A cross-sectional study was conducted among Iraqi university students using a structured questionnaire, including the DASS-21, Insomnia Severity Index, and Internet Addiction Test. Descriptive and inferential statistics were used to …
Thermochemical Conversion Of Oily Sludge, Composition, Hazards, And Treatment Strategies: An Overview, Mahmod A. Abdulqader
Thermochemical Conversion Of Oily Sludge, Composition, Hazards, And Treatment Strategies: An Overview, Mahmod A. Abdulqader
AUIQ Complementary Biological System
Oily sludge (OS) is considered one of the most complex by-products produced in the petroleum industry as an unwanted. This work aims to provide a comprehensive review focused on the dangers of stockpiled OS, its sources and contents, as well as its complex composition. This study also analyzes the global annual generation and stockpiling quantities of OS. Therefore, the thermochemical conversion, hydrothermal carbonization (HTC) char produced via HTC called hydrochar, pyrolysis (PY) char produced via PY named pyro-char, and microwave (MW) processes, while the char produced MW labeled micro-char. In conclusion, this study will facilitate researchers and provide a clear …
Resveratrol And Il-6 Modulation Of Cxcl1 Expression And Viability In Human Breast Cancer Cell Lines, Entkhab M. A. Alanisi, Aida H. Alobaidi, Khalid Alyodawi
Resveratrol And Il-6 Modulation Of Cxcl1 Expression And Viability In Human Breast Cancer Cell Lines, Entkhab M. A. Alanisi, Aida H. Alobaidi, Khalid Alyodawi
AUIQ Complementary Biological System
This study aims to investigate, through in vitro methods, the molecular, immunofluorescent, and immunohistochemical effects of resveratrol and IL-6 on CXCL1 gene/protein expression in human breast cancer cells (MCF-7). MCF-7 and MCF-10A cell lines were cultured and divided into four groups: control, IL-6-treated, resveratrol-treated, and a combination-treated group. CXCL1 gene expression was assessed by real-time PCR (RT-PCR), while CXCL1 protein levels were analyzed using immunofluorescence and immunohistochemistry. Cell viability was quantified by MTS assay using ELISA. CXCL1 gene/protein was overexpressed in MCF-7 cells, especially in the IL-6-treated group, but reduced in both resveratrol and combination-treated groups. MTS assay showed increased …
Synthesis And Characterization Of Schiff Base Compounds Produced From 6-Bromo-4-Fluoro-2 Aminobenzothazol Assessment Against Antibacterial Activity, Hiba I. Abdullah, Wissam M. R. Al-Joboury, Ibrahim F.O. Aljoboury, Ibtihal K. Hameed, Khalid A. Al-Badrany, Mahmod A. Abdulqader
Synthesis And Characterization Of Schiff Base Compounds Produced From 6-Bromo-4-Fluoro-2 Aminobenzothazol Assessment Against Antibacterial Activity, Hiba I. Abdullah, Wissam M. R. Al-Joboury, Ibrahim F.O. Aljoboury, Ibtihal K. Hameed, Khalid A. Al-Badrany, Mahmod A. Abdulqader
AUIQ Complementary Biological System
Schiff bases exhibit a wide range of biological activities, including antibacterial, antifungal, anticancer, and anti-inflammatory properties. The aim of study was to synthesized 2-amino-benzothiazole derivatives and showed their novel structure leads to potent antimicrobial activity. The Schiff base compounds derived from 6-bromo-4-fluoro-2-aminobenzothazol was prepared from the reaction of 6-bromo-4-fluoro-2-aminobenzothazol compound (W1) with potassium thiocyanate in the presence of bromine. Unsaturated Alpha-Beta (W2-6) compounds were obtained from the reaction of and aromatic benzaldehyd with para -hydroxy acetophenone in a basal medium. The interaction of alpha-beta - unsaturated compounds with 4,6-dichloro-2-aminobenzothiazole gives compounds (W7-11) 4-(1-(4,6-dichlorobenzothiazole-2-El amino) - 3-aryl) phenol. The prepared compounds …
Estimation Of Some Biomarkers Related To Bone Turnover In Iraqi Women, Wafaa Raji Alfatlawi
Estimation Of Some Biomarkers Related To Bone Turnover In Iraqi Women, Wafaa Raji Alfatlawi
AUIQ Complementary Biological System
Osteoporosis is defined as a heterogeneous bone disease that leads to weakening in the structure of bones. Bone structure remains dynamic throughout an individual’s life, it undergoes continuous growth and resorption in a specific mechanism called bone turnover. Osteoporosis assumes the perturbation of equilibrium of the growth to destruction towards the destructive away. Bone turnover markers consider as indicators for pathway of bone turning over, it classified into two groups: first group to build the bones, the second group to break it down. By using bio tests and assays, these markers can be evaluated to monitor the activity of the …
Assessing Knowledge, Attitudes, And Practices Regarding Refractive Errors And Spectacle Wear Among Children In Sana’A: A Cross-Sectional Study, Tariek Aldoais, Zakarya Rageh, Khaled Al-Hemyari, Saleh Altheeb, Abdulmogni Al-Barrag, Mahfouth Bamashmus
Assessing Knowledge, Attitudes, And Practices Regarding Refractive Errors And Spectacle Wear Among Children In Sana’A: A Cross-Sectional Study, Tariek Aldoais, Zakarya Rageh, Khaled Al-Hemyari, Saleh Altheeb, Abdulmogni Al-Barrag, Mahfouth Bamashmus
AUIQ Complementary Biological System
Background: Understanding the knowledge, attitudes, and practices (KAP) regarding refractive errors and spectacle use is essential for promoting eye health and effective vision correction, especially in children.
Objective: This study assessed the demographic characteristics, knowledge, attitudes, and practices of participants concerning refractive errors and spectacle use, focusing on correlations influencing these factors.
Methods: A cross-sectional study of 228 participants analyzed demographic data, duration of glasses use, and responses to a structured questionnaire on KAP related to refractive errors and spectacles.
Results: Among participants, 53.1% were female, and 45.2% were aged 8–13 years. Glasses use for 1–3 years was reported by …
Performative Biomechanics : Evolving Buildings Into Inhabitable Organisms, Josh Lopez
Performative Biomechanics : Evolving Buildings Into Inhabitable Organisms, Josh Lopez
Bachelor of Architecture Theses - 5th Year
There has always been a connection between biology and architecture. Michael Pawlyn, in Biomimicry in Architecture, coined “biomechanical designs” to describe structural techniques derived from creatures. This study investigates chitin-based creatures. Crustaceans, insects, and microscopic organisms all have exoskeletons in nature. With a focus on crabs, other crustaceans and bugs, this study examines and evaluates the formal characteristics of chitin-based organisms. The architectural creations of OXMAN, NOX, which was founded by Lars Spuybroek; and Lebbeus Woods are among those that are analyzed and studied due to their inspiration from living things. They follow functional effectiveness in nature, which is why …
Crispr-Induced Mutagenesis Of Arabidopsis Thaliana Gene Apetala3, Hazel Frans, Tara Phelps-Durr
Crispr-Induced Mutagenesis Of Arabidopsis Thaliana Gene Apetala3, Hazel Frans, Tara Phelps-Durr
SACAD: Scholarly Activities
This project aims to create CRISPR-CAS9 mutations in the APETELA3 (AP3) gene of the model plant Arabidopsis thaliana. AP3 is a class B gene critical to the petal and stamen development of Arabidopsis flowers. AP3 is defined in a MADS domain, which binds directly to DNA and may be responsible for the expression of the CaRG-box genes. AP3 works in conjunction with PISTILLATA (PI), AGAMOUS (AG), APETALA1 (AP1), and SEPALLATA (SEP) genes to specify the development in the second and third whorls of the flower. While several alleles of AP3 already exist, these alleles are strong alleles that knockout gene …