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Articles 1 - 6 of 6
Full-Text Articles in Biology
Monitoring Activity Of Drosophila Larvae: Impedance & Video Microscopy Measures, Ann Simone Cooper, Robin L. Cooper
Monitoring Activity Of Drosophila Larvae: Impedance & Video Microscopy Measures, Ann Simone Cooper, Robin L. Cooper
Biology Faculty Publications
No abstract provided.
Monitoring Heart Rate In Drosophila Larvae By Various Approaches, Sameera Dasari, Robin L. Cooper
Monitoring Heart Rate In Drosophila Larvae By Various Approaches, Sameera Dasari, Robin L. Cooper
Biology Faculty Publications
No abstract provided.
Monitoring Carbon Dioxide Production By Drosophila Larvae, Robin L. Cooper, D. Nicholas Mcletchie
Monitoring Carbon Dioxide Production By Drosophila Larvae, Robin L. Cooper, D. Nicholas Mcletchie
Biology Faculty Publications
No abstract provided.
The N-Terminal Prodomain Of Sv23 Is Essential For The Assembly Of A Functional Vitelline Membrane Network In Drosophila, Anita L. Manogaran, Gail L. Waring
The N-Terminal Prodomain Of Sv23 Is Essential For The Assembly Of A Functional Vitelline Membrane Network In Drosophila, Anita L. Manogaran, Gail L. Waring
Biological Sciences Faculty Research and Publications
The vitelline membrane is a specialized extracellular matrix that surrounds and protects the oocyte. Recent studies indicate that it also serves as a storage site for embryonic pattern determinants. sV23, a major vitelline membrane protein, is essential for the morphogenesis of the vitelline membrane as sV23 protein null mutants lay flaccid, infertile eggs. By analyzing a series of sV23 mutant transgenes in the sV23 protein null genetic background, we have shown that sV23 is secreted as a proprotein in functional excess and that C- and N-terminal prodomains are removed successively, following its deposition in the extracellular space. Although a target …
A Regulatory Code For Neurogenic Gene Expression In The Drosophila Embryo, Michele Markstein, Robert Zinzen, Peter Markstein, Ka Ping Yee, Albert Erives, Angela Stathopoulos, Michael Levine
A Regulatory Code For Neurogenic Gene Expression In The Drosophila Embryo, Michele Markstein, Robert Zinzen, Peter Markstein, Ka Ping Yee, Albert Erives, Angela Stathopoulos, Michael Levine
Michele Markstein
Bioinformatics methods have identified enhancers that mediate restricted expression in the Drosophila embryo. However, only a small fraction of the predicted enhancers actually work when tested in vivo. In the present study, co-regulated neurogenic enhancers that are activated by intermediate levels of the Dorsal regulatory gradient are shown to contain several shared sequence motifs. These motifs permitted the identification of new neurogenic enhancers with high precision: five out of seven predicted enhancers direct restricted expression within ventral regions of the neurogenic ectoderm. Mutations in some of the shared motifs disrupt enhancer function, and evidence is presented that the Twist and …
The Cohesion Protein Ord Is Required For Homologue Bias During Meiotic Recombination, Hayley A. Webber, Louisa Howard, Sharon E. Bickel
The Cohesion Protein Ord Is Required For Homologue Bias During Meiotic Recombination, Hayley A. Webber, Louisa Howard, Sharon E. Bickel
Dartmouth Scholarship
During meiosis, sister chromatid cohesion is required for normal levels of homologous recombination, although how cohesion regulates exchange is not understood. Null mutations in orientation disruptor (ord) ablate arm and centromeric cohesion during Drosophila meiosis and severely reduce homologous crossovers in mutant oocytes. We show that ORD protein localizes along oocyte chromosomes during the stages in which recombination occurs. Although synaptonemal complex (SC) components initially associate with synapsed homologues in ord mutants, their localization is severely disrupted during pachytene progression, and normal tripartite SC is not visible by electron microscopy. In ord germaria, meiotic double strand breaks appear …