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Drosophila Melanogaster As A Model For Male Reproductive System Ethanol Toxicity, Gbemisola Ilelaboye
Drosophila Melanogaster As A Model For Male Reproductive System Ethanol Toxicity, Gbemisola Ilelaboye
Seton Hall University Dissertations and Theses (ETDs)
Drosophila melanogaster has been extensively used in different types of research as a model organism due to its high reproductivity, short life span, and easy maintenance. In this paper, we examined drosophila as a model for ethanol toxicity in the male reproductive system. We developed three assays: The DAPI assay, sperm viability assay, and tubulin staining assay. The DAPI assay is a nuclear staining assay that assesses the effects of various ethanol concentrations in late spermiogenesis in which increased detrimental effects to the sperm bundles were observed. The second assay consisted of the sperm viability assay which showed an increase …
Apical Testis Structure And The Effects Of Cadmium Treatment On Spermatogenesis In Drosophila, Paulina J. Cardaci
Apical Testis Structure And The Effects Of Cadmium Treatment On Spermatogenesis In Drosophila, Paulina J. Cardaci
Seton Hall University Dissertations and Theses (ETDs)
The fruit fly Drosophila melanogaster is used extensively as a model for studying molecular, genetic and cellular aspects of human disease and physiology. Our lab has used D. melanogaster and related species to study the structure of the testis stem cell niche, as well as other aspects of spermatogenesis. We previously revealed a novel stem cell niche structure in D. pseudoobscura, a distant relative of D. melanogaster. The signaling center of the D. melanogaster stem cell niche has a well-characterized rosette arrangement of fasciclin-positive cells terms the “hub”. D. pseudoobscura, however, lacks a punctuate hub and instead displays a …