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Full-Text Articles in Biology
Testosterone Effects On Renal Norepinephrine Content And Release In Rats With Different Y Chromosomes, Thomas J. Jones, Gail Dunphy, Amy Milsted, Daniel Ely
Testosterone Effects On Renal Norepinephrine Content And Release In Rats With Different Y Chromosomes, Thomas J. Jones, Gail Dunphy, Amy Milsted, Daniel Ely
Biology Faculty Research
The Y chromosome in spontaneously hypertensive rats (SHR) and stroke-prone rats has been shown to contain a locus that contributes to the hypertensive effect; both the sympathetic nervous system and testosterone may be involved. The objective of this study was to look at the effects of testosterone on renal norepinephrine (NE) release and content in the isolated perfused kidney in different Y chromosome backgrounds. The study involved male SHR, Wistar-Kyoto rats (WKY), and 2 consomic strains with different Y chromosomes (n=5 to 8 per group). Adult animals were castrated, and implants containing testosterone propionate were placed at the base of …
Heritability Of Expression Of The 70kd Heat-Shock Protein In Drosophila Melanogaster And Its Relevance To The Evolution Of Thermotolerance, Robert A. Krebs, Martin E. Feder, Jeehyun Lee
Heritability Of Expression Of The 70kd Heat-Shock Protein In Drosophila Melanogaster And Its Relevance To The Evolution Of Thermotolerance, Robert A. Krebs, Martin E. Feder, Jeehyun Lee
Biological, Geological, and Environmental Faculty Publications
The principle inducible heat-shock protein of Drosophila melanogasrer, Hsp70, contributes to thermotolerance throughout the entire life cycle of the species but may also reduce fitness in some life stages. In principle, selection might maximize the benefits of Hsp70 expression relative to its costs by adjusting the magnitude of Hsp70 expression for each life-cycle stage independently. Therefore we examined whether the magnitude of Hsp70 ex pre sion varied during the life cycle and the relationship of this variation to several life-history traits. For 28 isofemale lines derived from a single natural population, estimates of heritable variation in Hsp70 expression ranged between …