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The Effects Of Estradiol Benzoate On Protein Synthesis By The Isolated Perfused Snake Liver, William Ralph Boone

Master's Theses

The effect s of estradios benzoate on protein synthesis by the isolated perfused liver of Natrix fasciata fasciata (Linnaeus, 1766), the southern banded water snake, were investigated. The incorpora­tion of carbon-14 labeled leucine into plasma protein of the liver perfusate was used as an index of protein synthesis by the perfused liver.

Both control and experimental livers demonstrated incorporation of the labeled leucine into plasma protein. However, estrogen treated livers expressed significantly greater incorporation of the amino acid into plasma protein giving an almost linear response. Total plasma protein levels were also significantly higher in the perfusions involving estrogen treated …