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Biology Commons

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Dartmouth Scholarship

2015

Dose-response relationship

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Full-Text Articles in Biology

Possible Synergistic Effects Of Thymol And Nicotine Against Crithidia Bombi Parasitism In Bumble Bees, Olivia Masi Biller, Lynn S. Adler, Rebecca E. Irwin, Caitlin Mcallister, Evan C. Palmer-Young Dec 2015

Possible Synergistic Effects Of Thymol And Nicotine Against Crithidia Bombi Parasitism In Bumble Bees, Olivia Masi Biller, Lynn S. Adler, Rebecca E. Irwin, Caitlin Mcallister, Evan C. Palmer-Young

Dartmouth Scholarship

Floral nectar contains secondary compounds with antimicrobial properties that can affect not only plant-pollinator interactions, but also interactions between pollinators and their parasites. Although recent work has shown that consumption of plant secondary compounds can reduce pollinator parasite loads, little is known about the effects of dosage or compound combinations. We used the generalist pollinator Bombus impatiens and its obligate gut parasite Crithidia bombi to study the effects of nectar chemistry on host-parasite interactions. In two experiments we tested (1) whether the secondary compounds thymol and nicotine act synergistically to reduce parasitism, and (2) whether dietary thymol concentration affects parasite …


Testing Dose-Dependent Effects Of The Nectar Alkaloid Anabasine On Trypanosome Parasite Loads In Adult Bumble Bees, Winston E. Anthony, Evan C. Palmer-Young, Anne S. Leonard, Rebecca E. Irwin, Lynn S. Adler Nov 2015

Testing Dose-Dependent Effects Of The Nectar Alkaloid Anabasine On Trypanosome Parasite Loads In Adult Bumble Bees, Winston E. Anthony, Evan C. Palmer-Young, Anne S. Leonard, Rebecca E. Irwin, Lynn S. Adler

Dartmouth Scholarship

The impact of consuming biologically active compounds is often dose-dependent, where small quantities can be medicinal while larger doses are toxic. The consumption of plant secondary compounds can be toxic to herbivores in large doses, but can also improve survival in parasitized herbivores. In addition, recent studies have found that consuming nectar secondary compounds may decrease parasite loads in pollinators. However, the effect of compound dose on bee survival and parasite loads has not been assessed. To determine how secondary compound consumption affects survival and pathogen load in Bombus impatiens, we manipulated the presence of a common gut parasite, …