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Effects Of Adrenalectomy On Hemoconcentration And Blood Ph, Urea And Electrolytes In The Mongolian Gerbil (Meriones Unguiculatus), Magally Aellos De Cova

Master's Theses

The effects of adrenalectomy on some blood profiles of the Mongolian gerbil, Meriones unguiculatus, were studied in order to clarify the possible causes of its short survival after adrenal ablation. Measurements of hematocrit, pH, urea and electrolytes were made 18, 24 and 30 hours after surgery. Results show the expected alterations: hemoconcentration, metabolic acidosis, high values of urea and disturbances in electrolytes. While hyponatremia was significant only after 24 hours, important hypochloremia was not present at any time. Hyperkalemia was the most significant alteration observed. It occurred as early as 18 hours after surgery, suggesting that it may be an …

The Role Of The Adrenal Gland In The Survival Of White Rats Subjected To The Parotid Toxin Of The Toad, Bufo Marinus, Mark A. Green

Master's Theses

Six groups of white labor atory rats were utilized in this experiment. A sham-operated group and an adrenalectomized group were used as controls. Four other groups were adrenalectomized and given replacement therapy of cortisone, deoxycorticosterone acetate, epinephrine, and norepinephrine. All groups were then given injections of toad toxin from the parotid glands of Bufo marinus. Their heart and breathing rates were recorded for 60 minutes.

All of the untreated adrenalectomized rats showed altered heart and breathing rates and were killed by the toxin. Cortisone and nor ­ epinephrine aided the adrenalectomiz ed rats to survive. but cortisone was the …