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Genes That Guide Growth Cones Along The C. Elegans Ventral Nerve Cord, Bruce Wightman, Renee Baran, Gian Garriga
Genes That Guide Growth Cones Along The C. Elegans Ventral Nerve Cord, Bruce Wightman, Renee Baran, Gian Garriga
Renee Baran
During nervous system development, growth cone pioneering and fasciculation contribute to nerve bundle structure. Pioneer growth cones initially navigate along neuroglia to establish an axon scaffold that guides later extending growth cones. In C. elegans, the growth cone of the PVPR neuron pioneers the left ventral nerve cord bundle, providing a path for the embryonic extensions of the PVQL and AVKR growth cones. Later during larval development, the HSNL growth cone follows cues in the left ventral nerve cord bundle provided by the PVPR and PVQL axons. Here we show that mutations in the genes enu-1, fax-1, unc-3, unc-30, unc-42 …
Root-Soil Contact For The Desert Succulent Agave Deserti Engelm. In Wet And Drying Soil, Gretchen North, P. Nobel
Root-Soil Contact For The Desert Succulent Agave Deserti Engelm. In Wet And Drying Soil, Gretchen North, P. Nobel
Gretchen North
To investigate the extent and size of root-soil air gaps that develop during soil drying, resin casts of roots of the desert succulent Agave deserti Engelm. were made in situ for container-grown plants and in the field. Plants that were droughted in containers for 7 and 14 d had 24 and 34% root shrinkage, respectively, leading to root-soil air gaps that would reduce the hydraulic conductivity at the root-soil interface by a factor of about 5. When containers were vibrated during drought, root-soil air gaps were greatly diminished, and the predicted conductivity at the interface was similar to that of …
The Pax-5 Gene Is Alternatively Spliced During B-Cell Development, Patty Zwollo, Hector Arrieta, Kaleo Ede, Karen Molinder, Stephen Desiderio, Roberta Pollock
The Pax-5 Gene Is Alternatively Spliced During B-Cell Development, Patty Zwollo, Hector Arrieta, Kaleo Ede, Karen Molinder, Stephen Desiderio, Roberta Pollock
Roberta Pollock
The transcription factor Pax-5 is expressed during the early stages of B-cell differentiation and influences the expression of several B-cell-specific genes. In addition to the existing isoform (Pax-5, which we have named Pax-5a), we have isolated three new isoforms, Pax-5b, Pax-5d, and Pax-5e, from murine spleen and B-lymphoid cell lines using library screenings and polymerase chain reaction amplification. Isoforms Pax-5b and Pax-5e have spliced out their second exon, resulting in proteins with only a partial DNA-binding domain. Isoforms Pax-5d and Pax-5e have deleted the 3′-region, which encodes the transactivating domain, and replaced it with a novel sequence. The existence of …