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Full-Text Articles in Biology

The Comparative Metabolism Of The Four Pyrrolizidine Alkaloids, Seneciphylline, Retrorsine, Monocrotaline, And Trichodesmine In The Isolated, Perfused Rat Liver., C. C. Yan, R. A. Cooper, R. J. Huxtable Jul 1995

The Comparative Metabolism Of The Four Pyrrolizidine Alkaloids, Seneciphylline, Retrorsine, Monocrotaline, And Trichodesmine In The Isolated, Perfused Rat Liver., C. C. Yan, R. A. Cooper, R. J. Huxtable

Roland A. Cooper

Despite their similarity in structure, pyrrolizidine alkaloids (PAs) vary in their LD50s and in the organs in which toxicity is expressed. We have examined whether there are differences in the metabolism of certain PAs that are associated with these quantitative and qualitative differences in toxicity. Isolated rat livers were perfused with one of four PAs (seneciphylline, retrorsine, monocrotaline, and trichodesmine) at 0.5 mM for 1 hr, and the pyrrolic metabolites determined that were released into perfusate and bile or bound in the liver. The proportion of the PA removed by the liver varied from 93% for retrorsine to 55% for …


The Nutritional Knowledge, Food Choices, And Exercise Habits Of Students At Langston University, Preston Solomon May 1995

The Nutritional Knowledge, Food Choices, And Exercise Habits Of Students At Langston University, Preston Solomon

McCabe Thesis Collection

The nutritional knowledge, food choice, and exercise habits of an individual determine his or her overall health and life expectancy. Information on these topics enables nutrition educators to develop strategies to improve knowledge and to tailor educational efforts which affect a large number of persons. Poor health in America today is an ever present reality. Heart disease, cancer, diabetes mellitus, cerebrovascular diseases, renal diseases, and pulmonary diseases are causes of death related in part to lack of nutritional knowledge and poor eating and exercise habits. A few of these diseases are chronic in nature and are the most deadly.

The …


Dynamic Diseases In Neurology And Psychiatry, John Milton, Deborah Black Mar 1995

Dynamic Diseases In Neurology And Psychiatry, John Milton, Deborah Black

WM Keck Science Faculty Papers

Thirty-two (32) periodic diseases of the nervous system are identified in which symptoms and/or signs recur. In 10/32, the recurrence of a symptom complex is one of the defining features of the illness, whereas in 22/32 oscillatory signs occur in the setting of an ongoing nervous system disorder. We discuss the possibility that these disorders may be dynamic diseases.


Dynamical Disease: Identification, Temporal Aspects And Treatment Strategies For Human Illness, Jacques Bélair, Leon Glass, Uwe An Der Heiden, John Milton Mar 1995

Dynamical Disease: Identification, Temporal Aspects And Treatment Strategies For Human Illness, Jacques Bélair, Leon Glass, Uwe An Der Heiden, John Milton

WM Keck Science Faculty Papers

Dynamical diseases are characterized by sudden changes in the qualitative dynamics of physiological processes, leading to abnormal dynamics and disease. Thus, there is a natural matching between the mathematical field of nonlinear dynamics and medicine. This paper summarizes advances in the study of dynamical disease with emphasis on a NATO Advanced Research Workshop held in Mont Tremblant, Quebec, Canada in February 1994. We describe the international effort currently underway to identify dynamical diseases and to study these diseases from a perspective of nonlinear dynamics. Linear and nonlinear time series analysis combined with analysis of bifurcations in dynamics are being used …


Normal Kinetic Patterns Of The Lower Extremities During Natural Walking In Children Aged Six To Ten, Thomas Ellexson, Christopher Nawrocki, Darrin Schober Jan 1995

Normal Kinetic Patterns Of The Lower Extremities During Natural Walking In Children Aged Six To Ten, Thomas Ellexson, Christopher Nawrocki, Darrin Schober

Masters Theses

The purpose of this research was to initiate a normative pediatric three-dimensional lower extremity kinetic database specific to the Mary Free Bed Hospital/Grand Valley State University Center for Human Kinetic Studies. Twenty healthy children (eleven girls and nine boys) with a mean age of 7.9 years volunteered for this study. Lower extremity kinetic data were obtained using a computerized three-dimensional motion analysis system coupled with a force plate. Kinematic and kinetic data were pooled and mean/standard deviations at each one percent of the gait cycle were determined for the twenty normative children. Results of the pediatric kinetic data were similar …


The Relationship Among Isokinetic Knee Parameters And Three Functional Tests, Kristen Brinks, Ronda Delong, Tanya Stout Jan 1995

The Relationship Among Isokinetic Knee Parameters And Three Functional Tests, Kristen Brinks, Ronda Delong, Tanya Stout

Masters Theses

The purpose of this study was to investigate the correlation between knee strength and endurance, as tested by the Biodex{dollar}\sp\circler{dollar} isokinetic system, and the lateral step-up, cross-over hop for distance, and triple hop for distance. Subjects included 20 males and 30 females aged 21-40 years with no history of low back, hip, knee, or ankle injury that was treated by a physician. Bilateral knee flexion and extension strength, power, and endurance was measured at 60, 180 and 300 degrees/second with the hip extended and flexed 115{dollar}\sp\circ{dollar}. Isokinetic data were normalized to body weight and correlated to hop distance which was …


The Effect Of Family Participation On The Outcome Of Patients With Traumatic Brain Injury In Rehabilitation, Grant Middleton, Brett Ransom Jan 1995

The Effect Of Family Participation On The Outcome Of Patients With Traumatic Brain Injury In Rehabilitation, Grant Middleton, Brett Ransom

Masters Theses

The purpose of this study was to explore the relationship between physical therapists' perceptions and institutional policies relating to family participation in rehabilitation and rehabilitation outcome of patients with traumatic brain injury. Utilizing surveys, we collected information about institutional policy from institutions that were members of the Commission for Accreditation of Rehabilitation Facilities (CARF) in the Midwestern United States. Thirteen institutional surveys provided usable Functional Independence Measure (FIM) scores for patients rehabilitated in 1993, which were used as the outcome measure. The therapists' perceptions survey (n = 104) gathered data about the belief of physical therapists relating to family involvement …


The Effects Of Partial Unweighting On Hemiplegic Gait, Natasha A. Creaser, Michael W. Jones Jan 1995

The Effects Of Partial Unweighting On Hemiplegic Gait, Natasha A. Creaser, Michael W. Jones

Masters Theses

This study investigated the effects of 30% body weight support on gait in two individuals with hemiplegia secondary to stroke. Two subjects with right hemiplegia were tested. Each completed four trials, two full weight bearing and two unweighted 30%, in random order. Each trial consisted of walking six meters on a treadmill at the subjects' self-selected speed. Temporal distance data were collected via Stride Analyzer footswitches. Subjects were also videotaped from the side during all trials. We expected velocity, cadence, stride length, uninvolved limb swing time, and involved limb stance time to increase with unweighting. Subjects 1's results agreed only …