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- Molecular docking, molecular dynamics, ADME-Tox (2)
- 22-kDa peripheral myelin protein (PMP22) (1)
- 3B (1)
- Adipocyte (1)
- Alpha-1-antitrypsin (1)
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- Anion-Quadrupole (1)
- Anion-pi (1)
- Biokimia dan Teknologi Farmasi: Desain Obat dan Vaksin dengan Pendekatan Biomedis Molekular (1)
- Castration (1)
- Cyclic peptide (1)
- Cyclin G2 (CCNG2) (1)
- Cyclin-dependent inhibitor 2C (CDKN2C) (1)
- Cysteine protease (1)
- ER (1)
- Endocrine Disruption (1)
- Estrogen Receptor (1)
- FISH Imaging (1)
- Fat deposition (1)
- GEO datasets (1)
- H1N1 (1)
- IL-10 (1)
- Image processing (1)
- Male pig (1)
- MicroRNA (1)
- Molecular Simulation (1)
- Molecular farming (1)
- Nanoscopy (1)
- PiMP (1)
- Silencing (1)
- Super-resolution (1)
- Publication
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Articles 1 - 7 of 7
Full-Text Articles in Bioinformatics
The Complexity Of Molecular Interactions And Bindings Between Cyclic Peptide And Inhibit Polymerase A And B1 (Pac-Pb1n) H1n1, Arli A. Parikesit, Harry Noviardi Hn, Djati Kerami Dk, Usman Sumo Friend Tambunan Usft
The Complexity Of Molecular Interactions And Bindings Between Cyclic Peptide And Inhibit Polymerase A And B1 (Pac-Pb1n) H1n1, Arli A. Parikesit, Harry Noviardi Hn, Djati Kerami Dk, Usman Sumo Friend Tambunan Usft
Arli A Parikesit
The influenza/H1N1 virus has caused hazard in the public health of many countries. Hence, existing influenza drugs could not cope with H1N1 infection due to the high mutation rate of the virus. In this respect, new method to block the virus was devised. The polymerase pac-pb1n enzyme is responsible for the replication of H1N1 virus. Thus, novel inhibitors were developed to ward off the functionality of the enzyme. In this research, cyclic peptides has been chosen to inhibit PAc-PB1n due to its proven stability in reaching the drug target. Thus, computational method for elucidating the molecular interaction between cyclic peptides …
Identification And Characterization Of Cysteine Protease Genes In Tobacco For Use In Recombinant Protein Production, Kishor Duwadi
Identification And Characterization Of Cysteine Protease Genes In Tobacco For Use In Recombinant Protein Production, Kishor Duwadi
Electronic Thesis and Dissertation Repository
Plants are an attractive host system for pharmaceutical protein production. Many therapeutic proteins have been produced and scaled up in plants at a low cost compared to the conventional microbial and animal based systems. The main technical challenge during this process is to produce sufficient level of proteins in plants. Low yield is generally caused by proteolytic degradation during expression and downstream processing of recombinant proteins. The yield of a human therapeutic protein interleukin (IL) -10 produced in transgenic tobacco leaves was found to be below the critical level, and is potentially due to degradation by tobacco cysteine proteases (CysPs). …
Applications And Improvements In The Molecular Modeling Of Protein And Ligand Interactions, Jason Bret Harris
Applications And Improvements In The Molecular Modeling Of Protein And Ligand Interactions, Jason Bret Harris
Doctoral Dissertations
Understanding protein and ligand interactions is fundamental to treat disease and avoid toxicity in biological organisms. Molecular modeling is a helpful but imperfect tool used in computer-aided toxicology and drug discovery. In this work, molecular docking and structural informatics have been integrated with other modeling methods and physical experiments to better understand and improve predictions for protein and ligand interactions. Results presented as part of this research include:
1.) an application of single-protein docking for an intermediate state structure, specifically, modeling an intermediate state structure of alpha-1-antitrypsin and using the resulting model to virtually screen for chemical inhibitors that can …
Biokimia Dan Teknologi Farmasi: Desain Obat Dan Vaksin Dengan Pendekatan Biomedis Molekular, Usman Sumo Friend Tambunan Usft, Arli A. Parikesit Aap
Biokimia Dan Teknologi Farmasi: Desain Obat Dan Vaksin Dengan Pendekatan Biomedis Molekular, Usman Sumo Friend Tambunan Usft, Arli A. Parikesit Aap
Arli A Parikesit
No abstract provided.
Differential Expression Of Cyclin G2, Cyclin Dependent Kinase Inhibitor 2c And Peripheral Myelin Protein 22 Genes During Adipogenesis..Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Jinsoo Ahn, Michael E. Davis, Kichoon Lee
Differential Expression Of Cyclin G2, Cyclin Dependent Kinase Inhibitor 2c And Peripheral Myelin Protein 22 Genes During Adipogenesis..Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Jinsoo Ahn, Michael E. Davis, Kichoon Lee
Jibin Zhang
Time Series Data For 3b Image Processing, George Mcnamara
Time Series Data For 3b Image Processing, George Mcnamara
George McNamara
Time series data for 3B image processing
Four time series data sets of Stellaris single molecules RNA FISH (fluorescence in situ hybridization). All four datasets are 301 imaqe planes. FISH probes are to TOP1 mRNA (Topoisomerase I)in Saos osterosarcoma cells.
One dataset is 10 millisecond exposures (very dim), acquired in Streaming acquisition mode (no hardware overhead).
The other three datasets are a three consecutive planes of the same XY field of view.
I have included image processing results for:
PiMP - a fast method developed by Sebastian Munck et al 2012, http://www.ncbi.nlm.nih.gov/pubmed/?term=22357945
and greatly improved performance by Glen Macdonald (Seattle). …
A Comprehensive Microrna Expression Profile Of The Backfat Tissue From Castrated And Intact Full-Sib Pair Male Pigs.Pdf, Ying Bai, Jinming Huang, Gang Liu, Jibin Zhang, Jianying Wang, Chengkun Liu, Meiying Fang
A Comprehensive Microrna Expression Profile Of The Backfat Tissue From Castrated And Intact Full-Sib Pair Male Pigs.Pdf, Ying Bai, Jinming Huang, Gang Liu, Jibin Zhang, Jianying Wang, Chengkun Liu, Meiying Fang
Jibin Zhang