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Full-Text Articles in Bioinformatics
Protein Structure – Based Method For Identification Of Horizontal Gene Transfer In Bacteria, Swetha Billa
Protein Structure – Based Method For Identification Of Horizontal Gene Transfer In Bacteria, Swetha Billa
Department of Computer Science and Engineering: Dissertations, Theses, and Student Research
Horizontal Gene Transfer is defined as the movement of genetic material from one strain of species to another. Bacteria, being an asexual organism were always believed to transfer genes vertically. But recent studies provide evidence that shows bacteria can also transfer genes horizontally.
HGT plays a major role in evolution and medicine. It is the major contributor in bacterial evolution, enabling species to acquire genes to adapt to the new environments. Bacteria are also believed to develop drug resistance to antibiotics through the phenomenon of HGT. Therefore further study of HGT and its implications is necessary to understand the effects …
Computational Complexity Of Approximate And Precise Data With Constraint Automaton, Dipty Singh
Computational Complexity Of Approximate And Precise Data With Constraint Automaton, Dipty Singh
Department of Computer Science and Engineering: Dissertations, Theses, and Student Research
The DNA molecules packaged in structures called chromosomes within the cells of living organisms encode hereditary information that is passed on to their offspring. Using transcription and translation, the genes within these DNA molecules help in protein synthesis. Thus chromosomal DNA serves as a blueprint for the chemical processes of life.
In order to analyze a DNA sequence by currently available technology, we have to cut it into small fragments, e.g. by using restriction enzymes. The application of different restriction enzymes to the multiple copies of the same DNA sequence generates many overlapping fragments. In order to construct the original …