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Aberrant coordination geometry

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Structure-Function Analysis And Characterization Of Metalloproteins., Sen Yao Aug 2016

Structure-Function Analysis And Characterization Of Metalloproteins., Sen Yao

Electronic Theses and Dissertations

Metalloproteins are proteins that can bind at least one metal ion as a cofactor. They utilize metal ions for a variety of biological purposes, and are essential for all domains of life. Due to the ubiquity of metalloprotein’s involvement across these processes across all domains of life, how proteins coordinate metal ions for different biochemical functions is of great relevance to understanding the implementation of these biological processes. One of the most important aspects of metal binding is its coordination geometry (CG), which often implies functional activities. Most of the current studies are based on the assumption of previously reported …