Open Access. Powered by Scholars. Published by Universities.®
Biochemistry, Biophysics, and Structural Biology Commons™
Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Specialized Metabolism In Retina, Retinal Pigmented Epithelium, And Testis, Siyan Zhu
Specialized Metabolism In Retina, Retinal Pigmented Epithelium, And Testis, Siyan Zhu
Graduate Theses, Dissertations, and Problem Reports
The retina and its neighboring retinal pigmented epithelium (RPE) are high energy-demanding and metabolically active tissues with specialized and complementary metabolism. They are metabolically interdependent and impact each other’s viability. Interestingly, many of the metabolic features in the retina and RPE are shared with the testis. For example, testis is also energy costly due to continuous sperm differentiation and it has similar metabolic inter-dependence between different testis cells. Both the retina and testis are vulnerable to mitochondrial metabolic impairments.
We conducted three research projects to understand 1) the nutrient utilization and communication in retina and RPE; 2) The profiling of …