Open Access. Powered by Scholars. Published by Universities.®

Biochemistry, Biophysics, and Structural Biology Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 3 of 3

Full-Text Articles in Biochemistry, Biophysics, and Structural Biology

Precise Repair Of Mping Excision Sites Is Facilitated By Target Site Duplication Derived Microhomology, David M. Gilbert, M. Catherine Bridges, Ashley E. Strother, Courtney E. Burckhalter, James M. Burnette Iii, C. Nathan Hancock Sep 2015

Precise Repair Of Mping Excision Sites Is Facilitated By Target Site Duplication Derived Microhomology, David M. Gilbert, M. Catherine Bridges, Ashley E. Strother, Courtney E. Burckhalter, James M. Burnette Iii, C. Nathan Hancock

Faculty Publications

A key difference between the Tourist and Stowaway families of miniature inverted repeat transposable elements (MITEs) is the manner in which their excision alters the genome. Upon excision, Stowaway-like MITEs and the associated Mariner elements usually leave behind a small duplication and short sequences from the end of the element. These small insertions or deletions known as “footprints” can potentially disrupt coding or regulatory sequences. In contrast, Tourist-like MITEs and the associated PIF/Pong/Harbinger elements generally excise precisely, returning the genome to its original state. The purpose of this study was to determine the mechanisms underlying these …


Functional, Sub-100 Nm Polymer Nanoparticles Via Thiol-Ene Miniemulsion Photopolymerization, Douglas Amato, Dahlia Amato, Alex S. Flynt, Derek L. Patton Aug 2015

Functional, Sub-100 Nm Polymer Nanoparticles Via Thiol-Ene Miniemulsion Photopolymerization, Douglas Amato, Dahlia Amato, Alex S. Flynt, Derek L. Patton

Faculty Publications

In this work, sub-100 nm crosslinked polythioether nanoparticles were synthesized via thiol–ene photopolymerization in miniemulsion using high-energy homogenization. The effects of the miniemulsion formulation and homogenization parameters – including inhibitor concentration, surfactant concentration, organic weight fraction, ultrasonication time and amplitude – on nanoparticle size and size distribution were investigated. Thiol–ene nanoparticles with a mean particle diameter of 46 nm were obtained under optimized conditions for the current system at 2.5 wt% organic fraction and 20 mM surfactant concentration. In an effort to demonstrate potential utility of thiol–ene nanoparticles, we exploit the step-growth radical mechanism of thiol–ene photopolymerization under non-stoichiometric conditions …


Evaluation Of The Performance Of A Rural Municipal Wastewater Treatment Plant In Nacogdoches, East Texas (Usa) (Abstract), Kefa Karimu Onchoke, Michael Janusa, Salomey Asantewaa Sasu Jan 2015

Evaluation Of The Performance Of A Rural Municipal Wastewater Treatment Plant In Nacogdoches, East Texas (Usa) (Abstract), Kefa Karimu Onchoke, Michael Janusa, Salomey Asantewaa Sasu

Faculty Publications

The performance of a rural wastewater treatment facility, Nacogdoches Wastewater Treatment Plant

(NWWTP), in East Texas, USA, was assessed from January 2013 through June 2014. The elemental concentrations (Na, Mg, Ca, Ni, Pb, Mn, Cr, Mo, and Cu, Al, As, B, Ba, Ag, Cd, Fe, Hg, K, Se, Zn, Co, P, and S) were measured using inductively coupled plasma optical emission spectrometry. The anion concentrations (Br−, NO3- , NO2- , PO34-,F−, Cl−, and SO24−) were measured by ion chromatography. In general, the NWWTP was found efficient in removal to ≥ 96% for metals. The removal efficiency for anions was in …