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University of Nebraska - Lincoln
Department of Biochemistry: Dissertations, Theses, and Student Research
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Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Identification And Characterization Of A Cadmium-Transporting P-Type Atpase In Yeast Saccharomyces Cerevisiae, David J. Adle
Identification And Characterization Of A Cadmium-Transporting P-Type Atpase In Yeast Saccharomyces Cerevisiae, David J. Adle
Department of Biochemistry: Dissertations, Theses, and Student Research
Detoxification and homeostatic acquisition of metal ions are vital for all living organisms. Non-physiological heavy metals are toxic at low concentrations and represent major environmental hazards to human health. In particular, cadmium is a toxic environmental pollutant linked to a number of ailments including cancer, kidney and bone disease and reproductive disorders. The biological effects of cadmium toxicity which lead to human disease and the cellular mechanisms for cadmium defense are ill defined. Thus, the study of heavy metal detoxification systems represents an important research avenue to help combat cadmium related disorders.
The goal of this research project was to …