Open Access. Powered by Scholars. Published by Universities.®
Biochemistry, Biophysics, and Structural Biology Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Discipline
Articles 1 - 3 of 3
Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
Manual And Automated Solid Phase Synthesis Of Peptides For Breast Cancer Cell Targeting, Savannah Carlson
Manual And Automated Solid Phase Synthesis Of Peptides For Breast Cancer Cell Targeting, Savannah Carlson
Student Scholar Symposium Abstracts and Posters
Four peptides were synthesized using solid phase peptide synthesis. The two target peptides synthesized were based off peptide 18-4 and its negative analog. Each were synthesized once manually, and once using an automatic peptide synthesizer. Peptide 18-4 has a high affinity for breast cancer cells, allowing it to be used to detect circulating tumor cells (CTCs) in blood (Kaur et. al, 2015). Manual solid phase peptide synthesis is performed by anchoring the first amino acid to Wang resin and coupling each Fmoc protected amino acid individually until the target sequence is achieved. To synthesize the peptides automatically, the automated Tribute …
A Pilot Study Analyzing Solvents In Electronic Cigarette “E-Liquid” Using High Performance Liquid Chromatography, Austin Matranga, Olivia Sellers, Matthew Gartner
A Pilot Study Analyzing Solvents In Electronic Cigarette “E-Liquid” Using High Performance Liquid Chromatography, Austin Matranga, Olivia Sellers, Matthew Gartner
Student Scholar Symposium Abstracts and Posters
Introduction: Electronic cigarettes, also known as an e-cigarette, are battery-powered devices that use a heating element to convert a liquid (“e-liquid”) into an inhalable aerosol. Their advertised use is as a nicotine delivery system minus the harmful chemicals. Since “e-liquids” and the electronic cigarettes are not regulated by the Food and Drug Administration, it is not well known under what conditions, if any, carcinogenic compounds are produced. There has been little research on the toxicity of electronic cigarettes. The aim of this study was to determine if formaldehyde or acetaldehyde are formed from the e-liquid by the high heat of …
Connecting The Physiological And Behavioral Response To Heat Stress On A Warming Planet, Anastasia Kalyta
Connecting The Physiological And Behavioral Response To Heat Stress On A Warming Planet, Anastasia Kalyta
Student Scholar Symposium Abstracts and Posters
Intertidal communities are considered good models of the biological effects of climate change on ecosystems, as their resident organisms are subjected to heat spells during daytime low tides. The increasing heat exposure can elicit behavioral as well as physiological responses in intertidal organisms. We studied the relationship between these responses to heat stress in the blue-banded hermit crab, Pagurus samuelis, by inducing a “heat shock” with elevated water temperature of 29 °C for 2.5 h. The behavioral effect of heat-shock was quantified using a 30-minute feeding assay, measuring the mass of a standard squid pellet consumed by individual hermit crabs. …