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Biochemistry, Biophysics, and Structural Biology Commons™
Open Access. Powered by Scholars. Published by Universities.®
- Keyword
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- Molecular docking, molecular dynamics, ADME-Tox (3)
- Bindingless signal delivery (1)
- Biokimia dan Teknologi Farmasi: Desain Obat dan Vaksin dengan Pendekatan Biomedis Molekular (1)
- Cyclic peptide (1)
- H1N1 (1)
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- Human cells (1)
- JFI2013 (1)
- Microfluidics (1)
- Molecular Simulation (1)
- The In Silico Molecular Interaction of Organoboron Compounds as Curative Measure toward Cervical Cancer (1)
- Time-delayed switched system; Optimal control; Switching instants; Smoothing approximation; Fed-batch process (1)
- Virology (1)
- Publication
Articles 1 - 5 of 5
Full-Text Articles in Biochemistry, Biophysics, and Structural Biology
The Complexity Of Molecular Interactions And Bindings Between Cyclic Peptide And Inhibit Polymerase A And B1 (Pac-Pb1n) H1n1, Arli A. Parikesit, Harry Noviardi Hn, Djati Kerami Dk, Usman Sumo Friend Tambunan Usft
The Complexity Of Molecular Interactions And Bindings Between Cyclic Peptide And Inhibit Polymerase A And B1 (Pac-Pb1n) H1n1, Arli A. Parikesit, Harry Noviardi Hn, Djati Kerami Dk, Usman Sumo Friend Tambunan Usft
Arli A Parikesit
The influenza/H1N1 virus has caused hazard in the public health of many countries. Hence, existing influenza drugs could not cope with H1N1 infection due to the high mutation rate of the virus. In this respect, new method to block the virus was devised. The polymerase pac-pb1n enzyme is responsible for the replication of H1N1 virus. Thus, novel inhibitors were developed to ward off the functionality of the enzyme. In this research, cyclic peptides has been chosen to inhibit PAc-PB1n due to its proven stability in reaching the drug target. Thus, computational method for elucidating the molecular interaction between cyclic peptides …
The In Silico Molecular Interaction Of Organoboron Compounds As Curative Measure Toward Cervical Cancer, Ridla Bakri Rb, Arli A. Parikesit, Cipta Prio Satryanto Cps, Djati Kerami Dk, Usman Sumo Friend Tambunan Usft
The In Silico Molecular Interaction Of Organoboron Compounds As Curative Measure Toward Cervical Cancer, Ridla Bakri Rb, Arli A. Parikesit, Cipta Prio Satryanto Cps, Djati Kerami Dk, Usman Sumo Friend Tambunan Usft
Arli A Parikesit
No abstract provided.
Experimental Demonstration Of Bindingless Signal Delivery In Human Cells Via Microfluidics, Fang-Tzu Chuang
Experimental Demonstration Of Bindingless Signal Delivery In Human Cells Via Microfluidics, Fang-Tzu Chuang
Fang-Tzu Chuang
The cellular signal transduction is commonly believed to rely on the direct “contact” or “binding” of the participating molecule reaction that depends positively on the corresponding molecule concentrations. In living systems, however, it is somewhat difficult to precisely match the corresponding rapid “binding,” depending on the probability of molecular collision, existing in the cellular receptor-ligand interactions. Thus, a question arises that if there is another mechanism (i.e., bindingless) that could promote this signal communication. According to this hypothesis, we report a cellular model based on the examination of intracellular calcium concentration to explore whether the unidentified signal delivery in cells …
Biokimia Dan Teknologi Farmasi: Desain Obat Dan Vaksin Dengan Pendekatan Biomedis Molekular, Usman Sumo Friend Tambunan Usft, Arli A. Parikesit Aap
Biokimia Dan Teknologi Farmasi: Desain Obat Dan Vaksin Dengan Pendekatan Biomedis Molekular, Usman Sumo Friend Tambunan Usft, Arli A. Parikesit Aap
Arli A Parikesit
No abstract provided.
Modelling And Optimal Control Of A Time-Delayed Switched System In Fed-Batch Process, Chongyang Liu, Zhaohua Gong
Modelling And Optimal Control Of A Time-Delayed Switched System In Fed-Batch Process, Chongyang Liu, Zhaohua Gong
Chongyang Liu
The main control goal of the fed-batch process is to maximize the yield of target product as well as to minimize the operation costs simultaneously. Considering the existence of time delay and the switching nature in the fed-batch process, a time-delayed switched system is proposed to formulate the 1,3-propanediol (1,3-PD) production process. Some important properties of the system are also discussed. Taking the switching instants and the terminal time as the control variables, a free terminal time delayed optimal control problem is then presented. Using a time-scaling transformation and parameterizing the switching instants into new parameters, an equivalently optimal control …