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Full-Text Articles in Poultry or Avian Science
Avian And Mammalian Facilitative Glucose Transporters, Mary Shannon Byers, Christianna Howard, Xiaofei Wang
Avian And Mammalian Facilitative Glucose Transporters, Mary Shannon Byers, Christianna Howard, Xiaofei Wang
Biology Faculty Research
The GLUT members belong to a family of glucose transporter proteins that facilitate glucose transport across the cell membrane. The mammalian GLUT family consists of thirteen members (GLUTs 1–12 and H+-myo-inositol transporter (HMIT)). Humans have a recently duplicated GLUT member, GLUT14. Avians express the majority of GLUT members. The arrangement of multiple GLUTs across all somatic tissues signifies the important role of glucose across all organisms. Defects in glucose transport have been linked to metabolic disorders, insulin resistance and diabetes. Despite the essential importance of these transporters, our knowledge regarding GLUT members in avians is fragmented. It is clear that …