Animal Sciences Commons^™

Construction Of A Cpsa Double Mutant To Determine The Function Of The Lyt-R Domain, Klarissa Klier

Honors College

Streptococcus agalactiae, otherwise known as Group B Streptococcus (GBS), is a zoonotic, Gram-positive, commensal and invasive bacteria which is the leading cause of neonatal bacterial infections. These bacterial infections include sepsis, meningitis, pneumonia, and bacteremia. In neonates, GBS is most commonly transferred to the child in utero or during birth when the child aspirates amniotic or vaginal fluids. GBS can also infect the child through the bloodstream while in utero, causing premature births or still births. Children who survive the initial infection develop severe morbidities which include mental retardation, cerebral palsy, and seizures. GBS can also affect immunocompromised adults, …