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Full-Text Articles in Animal Sciences
Alternative Nad(P)H Dehydrogenase And Alternative Oxidase: Proposed Physiological Roles In Animals, Allison Mcdonald, Dmytro V. Gospodaryov
Alternative Nad(P)H Dehydrogenase And Alternative Oxidase: Proposed Physiological Roles In Animals, Allison Mcdonald, Dmytro V. Gospodaryov
Biology Faculty Publications
The electron transport systems in mitochondria of many organisms contain alternative respiratory enzymes distinct from those of the canonical respiratory system depicted in textbooks. Two of these enzymes, the alternative NADH dehydrogenase and the alternative oxidase, were of interest to a limited circle of researchers until they were envisioned as gene therapy tools for mitochondrial disease treatment. Recently, these enzymes were discovered in several animals. Here, we analyse the functioning of alternative NADH dehydrogenases and oxidases in different organisms. We propose that both enzymes ensure bioenergetic and metabolic flexibility during environmental transitions or other conditions which may compromise the operation …
Expression Of Alternative Oxidase In The Copepod T. Californicus When Exposed To Environmental Stressors, Carly Tward
Expression Of Alternative Oxidase In The Copepod T. Californicus When Exposed To Environmental Stressors, Carly Tward
Theses and Dissertations (Comprehensive)
In addition to the typical electron transport system in animal mitochondria responsible for oxidative phosphorylation, some species possess an alternative oxidase (AOX) pathway, which causes electrons to bypass proton pumping complexes. Although AOX appears to be energetically wasteful, studies have revealed its wide taxonomic distribution, and indicate it plays a role in environmental stress tolerance. AOX discovery in animals is recent, and further research into its expression, regulation, and physiological role has been impeded by the lack of an experimental model organism. DNA database searches using bioinformatics revealed an AOX sequence present in the arthropod Tigriopus californicus. Multiple sequence …
Happy Or Hangry Families: Does Kinship Mediate Cooperation And Cannibalism In Drosophila Melanogaster Larvae?, Lucas Khodaei
Happy Or Hangry Families: Does Kinship Mediate Cooperation And Cannibalism In Drosophila Melanogaster Larvae?, Lucas Khodaei
Theses and Dissertations (Comprehensive)
The fruit fly Drosophila melanogaster has a long history as a research model for studies on behaviour and group dynamics. When individuals are grouped in an environment and resources decrease, then they may behave co-operatively with one another or antagonistically compete. Hamilton’s Law states that if the benefit of helping a related individual out-weighs the cost to its direct fitness, then the individual’s indirect fitness will increase when they help their kin compared to helping an unrelated stranger. Yet it is unknown whether kinship mediates larval behaviour to encourage co-operation and/or lessen antagonistic behaviours between consanguineous individuals. In this thesis …