Animal Sciences Commons^™

Isolation And Characterization Of Autosomal Male Sterile Mutants In Drosophila Melanogaster, Lynn J. Romrell

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

In order to study the genetic control of spermiogenesis, recessive, male-sterile, autosomal mutants of Drosophila melanogaster were induced with ethyl methanesulfonate. A total of 31 mutants were recovered, 15 of which were located on the second chromosome and 16 on the third chromosome. Eight second- and 6 third-chromosome mutants demonstrating sterility in all homozygous males were used for further analysis.

Complementation tests showed that 2 of the 8 second chromosome mutants (and none of the 6 third chromosome mutants) were noncomplementing, indicating that two of the mutants produced were alleles of the same locus. Mapping of the second chromosome mutants …

The Effects Of Formaldehyde On The Frequency Of Reversion Of The White-Ivory Mutant Of Drosophila Melanogaster, Ruth Ellen D. Wood

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

This study is an analysis of the effects of formaldehyde, a chemical which is both recombinogenic and mutagenic, on white-ivory (wⁱ) a highly mutable allele of the white locus of Drosophila. Formaldehyde is shown to significantly increase the reversion frequency of wⁱ. The results of this investigation differ from earlier observations in three respects: (1) there is a positive correlation between RNA (ribonucleic acid) concentration and reversion frequency in the presence of formaldehyde, but reversion does not appear to be totally RNA dependent; (2) female germ cells are more sensitive than those of the male; …