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Animal Sciences Commons

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Zoology

TÜBİTAK

2019

Toxicity

Articles 1 - 2 of 2

Full-Text Articles in Animal Sciences

All Aspects Of The Toxic Effects Of Lipopolysaccharide On Rat Liver And The Protective Effect Of Vitamin E And Sodium Selenite, Di̇lek Pandir, Sedat Per, Züleyha Doğanyi̇ği̇t, Fati̇h Oğuz Bekdemi̇r, Gülşi̇fe Gök, Ali̇ Demi̇rbağ Jan 2019

All Aspects Of The Toxic Effects Of Lipopolysaccharide On Rat Liver And The Protective Effect Of Vitamin E And Sodium Selenite, Di̇lek Pandir, Sedat Per, Züleyha Doğanyi̇ği̇t, Fati̇h Oğuz Bekdemi̇r, Gülşi̇fe Gök, Ali̇ Demi̇rbağ

Turkish Journal of Zoology

This work was planned to research the effects of lipopolysaccharide (LPS) and/or vitamin E (VE) and sodium selenite (SS), which have antioxidant properties, administered to the liver tissue of male rats. For this purpose, histopathology, immunohistochemistry, antioxidant capacity, terminal deoxynucleotidyl transferase (TdT) dUTP nick-end labeling assay, liver function, and DNA structure tests were performed. The lipid profile was also evaluated in this study. Rats that were administered LPS were treated with VE and/or SS. The liver function tests and lipid profile parameters showed statistically significant changes and histological alterations in the LPS treated groups. The number of cells entering apoptosis …


Acute And Chronic Effects Of Thifluzamide On Daphnia Magna, Feyza İçoğlu Aksakal Jan 2019

Acute And Chronic Effects Of Thifluzamide On Daphnia Magna, Feyza İçoğlu Aksakal

Turkish Journal of Zoology

Thifluzamide is a thiazole carboxanilide fungicide used to control a wide range of basidiomycete diseases on maize, potatoes, rice, and other crops. Although this fungicide is found in aquatic environments, there is no information about its acute and chronic toxicity on aquatic invertebrates. In the present study, to investigate acute and chronic toxicity of thifluzamide, daphnids were exposed to 1.25, 1.5, 2, and 2.5 mg/L thifluzamide for 48 h and 21 days, respectively. The expression of four oxidative stress-related genes (CAT, GCLC, GST, and GPX) and life-history parameters such as days to the first brood, days to the first egg …