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Changsha University of Science and Technology
Alkali hydrolysis; anion solid phase extraction column; liquid chromatography-tandem mass spectrometry; olaquindox; 3-methyl-quinoxaline-2-carboxylic acid
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Full-Text Articles in Agriculture
Quick Determination Of 3-Methyl-Quinoxaline-2-Carboxylic Acid Residues In Animal-Derived Food By Alkali Hydrolysis-Solid Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry, Liu Di, Han Li, Zeng Ni, Yu Tingting, Wang Heng, Wang Bin, Rong Mao
Quick Determination Of 3-Methyl-Quinoxaline-2-Carboxylic Acid Residues In Animal-Derived Food By Alkali Hydrolysis-Solid Phase Extraction-Liquid Chromatography-Tandem Mass Spectrometry, Liu Di, Han Li, Zeng Ni, Yu Tingting, Wang Heng, Wang Bin, Rong Mao
Food and Machinery
A rapid quasi-deterministic quantitative method for the determination of 3-methyl-quinoxaline-2-carboxylic acid (MQCA) residues in olaquindox metabolites of animal-derived foods was developed, by using liquid chromatography-tandem mass spectrometry (LC-MS/MS). The sample tissue was extracted by alkaline hydrolysis to extract MQCA, purified by anion solid phase extraction column, and detected by LC-MS/MS, and then quantified by internal standard method. The results showed that MQCA had a good linear relationship in the concentration range of 0.5～50.0 ng/mL, and the correlation coefficient was 0.999 7. The detection limit of MQCA was 0.1 μg/kg. The recovery rate was 95.6%～108.2% at the addition level of 0.1, …