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Full-Text Articles in Agriculture
Bhlh Iridoid Synthesis 3 Is A Member Of A Bhlh Gene Cluster Regulating Terpenoid Indole Alkaloid Biosynthesis In Catharanthus Roseus, Sanjay Kumar Singh, Barunava Patra, Priyanka Paul, Yongliang Liu, Sitakanta Pattanaik, Ling Yuan
Bhlh Iridoid Synthesis 3 Is A Member Of A Bhlh Gene Cluster Regulating Terpenoid Indole Alkaloid Biosynthesis In Catharanthus Roseus, Sanjay Kumar Singh, Barunava Patra, Priyanka Paul, Yongliang Liu, Sitakanta Pattanaik, Ling Yuan
Kentucky Tobacco Research and Development Center Faculty Publications
Basic helix‐loop‐helix (bHLH) transcription factors (TFs) are key regulators of plant specialized metabolites, including terpenoid indole alkaloids (TIAs) in Catharanthus roseus. Two previously characterized subgroup‐IVa bHLH TFs, BIS1 (bHLH Iridoid Synthesis 1) and BIS2 regulate iridoid biosynthesis in the TIA pathway. We reanalyzed the recently updated C. roseus genome sequence and discovered that BIS1 and BIS2 are clustered on the same genomic scaffold with a previously uncharacterized bHLH gene, designated as BIS3. Only a few bHLH gene clusters have been studied to date. Comparative analysis of 49 genome sequences from different plant lineages revealed the presence of analogous …