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Full-Text Articles in Agriculture
Preparation Of Ink Melanin From Sepia Esculenta By Ultrasound-Assisted And Its Protective Effects On Oxidative Damage In Caco-2 Cells, Zhang Jing-Yu, Xie Wan-Cui, Che Hong-Xia, Yang Xi-Hong
Preparation Of Ink Melanin From Sepia Esculenta By Ultrasound-Assisted And Its Protective Effects On Oxidative Damage In Caco-2 Cells, Zhang Jing-Yu, Xie Wan-Cui, Che Hong-Xia, Yang Xi-Hong
Food and Machinery
In order to investigate the protective effect of Sepia esculenta ink melanin on the oxidative damage of human cloned colon adenocarcinoma cells (Caco-2), the ultrasound-assisted method was used to prepare Sepia esculenta ink melanin and its structure characterization and antioxidant capacity were measured. In this study, 150 μmol/L tert-butyl hydrogen peroxide (TBHP) was used to induce the oxidative damage model of Caco-2 cells, and the cell survival rate was determined by the MTT method, as well as the activity of superoxide dismutase (SOD) and malondialdehyde (MDA) in cells were determined. The experimental results showed that the melanin extracted by ultrasound …
Study On Intervention Effects Of Electrophilic Components From Xiaoheiyao Against Free Fatty Acid-Induced Steatosis In Hepg2 Cells, Dong Wen-Le, Jiang Yu-Ge, Xia Shu-Fang, Cao Cong-Cong, Zhao Wei, Cheng Xiang-Rong
Study On Intervention Effects Of Electrophilic Components From Xiaoheiyao Against Free Fatty Acid-Induced Steatosis In Hepg2 Cells, Dong Wen-Le, Jiang Yu-Ge, Xia Shu-Fang, Cao Cong-Cong, Zhao Wei, Cheng Xiang-Rong
Food and Machinery
The electrophilic components in Xiaoheiyao were knocked out by GSH functionalized magnetic nanoparticles (GSH-MNPs) and characterized by LC-MS analysis, and the effect and mechanism of the electrophilic components in Xiaoheiyao for reducing lipid accumulation and oxidative stress in hepatocytes were evaluated, based on free fatty acid (FFA)-induced HepG2 cells. The ethyl acetate fraction was determined as the most electrophilic components-enriched part of Xiaoheiyao. At the concentration of 0.5~2.0 μg/mL, the petroleum ether, ethyl acetate and water fractions of Xiaoheiyao exhibited the activities of decreasing hepatic lipid accumulation and ROS production, in which the ethyl acetate fraction showed the best activities. …
Effects Of A Formula Containing Vitamin B On Ameliorates Anxious/Depression-Like Behaviors In An C57bl/6 Mice Model, Zhu Xi-Ping, Li Wen-Zhi, Tao Qian, He Wen-Jiang, Cui Chun
Effects Of A Formula Containing Vitamin B On Ameliorates Anxious/Depression-Like Behaviors In An C57bl/6 Mice Model, Zhu Xi-Ping, Li Wen-Zhi, Tao Qian, He Wen-Jiang, Cui Chun
Food and Machinery
Investigated effects of vitamin B complex TRP peptides and SOD on the anti-oxidative activity in brain tissue, serum inflammatory factor levels and reverse anxious/depression-like behaviors. Vitamin B complex TRP peptide and SOD (VB3︰ VB6︰TRP peptide︰SOD = 2︰10︰3︰4; VBPS) high, medium and low gavage doses were 260, 195, 130 mg/(kg·d), respectively. Studies showed that VBPS could reverse the anxious/depression-like behaviors and the slow body weight gain, with VBPS at a high dose being more effective. VBPS showed to control the effects of serum inflammatory cytokines (TNF-α, IL-6, IL-1β and IFN-γ), decrease malondialdehyde (MDA) levels and increase superoxide …