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Full-Text Articles in Agriculture
New Insight Into The Effects Of Small Heat Shock Proteins On Callipyge Lamb Meat Tenderness, Traci Cramer, Yuan H Brad Kim, Danyi Ma, Jolena N. Waddell, Moriah Penick
New Insight Into The Effects Of Small Heat Shock Proteins On Callipyge Lamb Meat Tenderness, Traci Cramer, Yuan H Brad Kim, Danyi Ma, Jolena N. Waddell, Moriah Penick
The Summer Undergraduate Research Fellowship (SURF) Symposium
Callipyge lambs are a type of sheep that are genetically known to produce tough meat. High expression of calpastatin, which inhibits proteolytic activity of µ-calpain, has been identified as the main factor behind the toughness of callipyge lamb meat. Another group of proteins called small heat shock proteins (sHSP) has recently been suggested for its possible involvement in tenderness development of meat, where up-regulation of sHSP may be associated with toughness. However, the role of sHSP in meat tenderization of callipyge lambs has never been investigated; therefore, the objective of this study is to determine possible involvement of sHSP in …
Genes With Physiological Roles In Callipyge Muscle Hypertrophy, Hui Yu
Genes With Physiological Roles In Callipyge Muscle Hypertrophy, Hui Yu
Open Access Dissertations
Callipyge sheep is an excellent model to study genes regulation in muscle growth since the up-regulation of DLK1 and/or RTL1 results in extreme postnatal muscle hypertrophy in loin and hindquarters. DLK1 and/or RTL1 are the primary inducers of muscle hypertrophy due to the inheritance model for the callipyge phenotype. The overall aim of this dissertation is to study the physiological pathways responding to the up-regulation of DLK1 and / or RTL1 in the hypertrophied muscles. Microarray analysis of gene expression identified 375 genes that were differentially expressed in callipyge semimembranosus. Twenty-five transcripts were further verified by quantitative PCR in two …