Life Sciences Commons^™

The Abundance Of Soil Microbes In Relationship To Proximity To The Urban Area Of Lancer Park In Farmville, Virginia, Christian Michael, Callie Cutrell, Miguel Diaz-Montealegre

Spring Showcase for Research and Creative Inquiry

Soil microbes are microorganisms found in soil that serve various critical roles and functions in the environment, such as decomposition and the cycling of nutrients in ecosystems. Natural and human-caused factors can have positive and/or negative impacts on soil microbes. The objective of this study is to examine the abundance of soil microbes in relationship to proximity to the urban area of Lancer Park in Farmville, Virginia. Soil samples were taken from four locations within Lancer Park: the upper and lower floodplain of Buffalo Creek, the bottom of a large stormwater detention pond, and adjacent to an ephemeral channel connecting …

Combined Effects Of Allelochemical And Pesticide Treatment On The Growth Of Cucumber Plants, Samue Morgan

Spring Showcase for Research and Creative Inquiry

Allelochemicals are biochemicals produced by one plant that inhibits the success of other plants in its vicinity. These allelochemicals are sometimes produced naturally or as a result of stimulus or stress. Ferulic acid is a widespread allelochemical found in cucumbers (Cucumis sativus). Artificial inhibitory chemicals such as the pesticide zeta cypermethrin may create new interactions with ferulic acid. We found that cucumbers acclimate to ferulic acid over time while the inhibitory effects of pesticide remained relatively constant over 14 days.

Activating The Innate Immune Response By Utilizing Macrophages As Aâ Defense For Immunosuppressed Individuals And Covid-19, Ashley Coddington, Christina Amoruso, Emma Rogers

Spring Showcase for Research and Creative Inquiry

The activation of the innate immune response by utilizing Interferon-Gamma to activate macrophages will provide for immunosuppressed individuals an additional treatment option for COVID-19.

Covid-19 Vaccine Distribution For The Homeless Population In Virginia, Brandi Joyner, Hunter Gillespie, Terika Williams

Spring Showcase for Research and Creative Inquiry

Due to the lack of proper personal hygiene, clean water and housing, the homeless population is more susceptible to infections. In addition, the homeless are more likely to have compromised immune systems (i.e., HIV/AIDS) due to illicit drug use and sex work. Furthermore, there is not a current systematic state program that allows feasible access to the COVID-19 vaccine due to limited internet access and/or phone access. We are proposing that the Virginia House of Delegates provide state funding for vaccination drives in areas with high poverty rates. Locations can be at soup kitchens, food banks, domestic abuse shelters, and …

Microhabitats In An Urban Greenspace: Function In The Beauty, Kalie Schultz

Honors Projects

This project combines science with art, with a focus on microhabitats in a unique natural space in an urban area. It is set in the Highlands Nature Preserve and the mediums used are photography and digital illustration. The goal of the project is to bring the viewer in from a wide, landscape perspective into a more close and detailed perspective of the multiple microhabitats that exist in the nature preserve. It shows how beauty can be hiding in plain sight for anyone to see if they look close enough. It also aims to show how the beauty is not just …

Evolution And Development Of Staminodes In Paronychia (Caryophyllaceae), Andrea D. Appleton

Honors College Theses

Staminodes are infertile stamens that have evolved numerous times in flowering plants and exhibit a vast array of forms and functions. Variation in staminodes suggests that numerous evolutionary processes underlie their origins, but to understand their how and why they evolved, comparative studies are needed in groups of closely related species. Identifying structures as staminodes is not always straightforward and sometimes requires corroborating phylogenetic and developmental evidence. Staminodial structures in Paronychia (Caryophyllaceae), for example, vary in shape and size and have been referred to as both petals and staminodes, rendering their homology uncertain. The development of staminodes was compared across …

Synopsis Of The Tribe Platynini In New Zealand (Coleoptera: Carabidae), André Larochelle, Marie-Claude Larivière

Insecta Mundi

The tribe Platynini (Coleoptera: Carabidae: Harpalinae) is revised for New Zealand. Eight genera and forty-three species are recognized.

Four genera and sixteen species are described as new: Ctenognathus davidsoni Larochelle and Larivière new species, Ctenognathus earlyi Larochelle and Larivière new species, Ctenognathus garnerae Larochelle and Larivière new species, Ctenognathus hoarei Larochelle and Larivière new species, Ctenognathus kaikoura Larochelle and Larivière new species, Ctenognathus marieclaudiae Larochelle new species, Ctenog­nathus perumalae Larochelle and Larivière new species, Ctenognathus takahe Larochelle and Larivière new species, Ctenognathus tawanui Larochelle and Larivière new species, Ctenognathus tepaki Larochelle …

Osmosis - Spring 2020

Osmosis Magazine

Osmosis is a student read, led, and written publication from the University of Richmond, focusing on all aspects of healthcare and science.

Examining The Mechanistic Roles Of Integrin Alpha-6 In Cancer Metastasis., Chase T. Clark

Honors College Theses

Metastasis- the spread of cancer cells from the primary tumor to the surrounding tissues- is responsible for 90% of cancer deaths. Integrin alpha-6 (ITGA6) is a specific transmembrane cell surface protein that functions in cell surface adhesion and signaling. ITGA6 is upregulated in many types of cancers and promotes the migration and invasion of cancer cells to surrounding tissues. It is my objective to determine the mechanism through which ITGA6 facilitates the migration of cancer cells through the extracellular matrix (ECM). These experiments helped to establish the role of ITGA6 in tumor development and provide focus for possible chemotherapeutic treatment. …

Osmosis - Spring 2019

Osmosis Magazine

Osmosis is a student read, led, and written publication from the University of Richmond, focusing on all aspects of healthcare and science.

Osmosis - Fall 2019

Osmosis Magazine

Osmosis is a student read, led, and written publication from the University of Richmond, focusing on all aspects of healthcare and science.

Rhetorical Field Methods For Science Communication Bes 521, Michael Cerbo

Library Impact Statements

No abstract provided.

Effects Of Varying Heat Indexes On Habitat Utilization And Behavior On Captive Red-Ruffed Lemurs (Varecia Rubra), Jeffrey Gammon

The Pegasus Review: UCF Undergraduate Research Journal

The two captive red-ruffed lemurs (Varecia rubra) at the Central Florida Zoo experienced a more temperate climate and utilized a differing habitat than they would in their native range, Madagascar. Proper management of the species in captivity is crucial for its long-term survival as they are critically endangered. Over a four month period, heat index temperature, lemur behavior, and habitat utilization data were collected via an instantaneous scan sample. Variables were analyzed to characterize how variations in heat index alter habitat utilization and behavior of the captive lemurs. As the heat index increased, habitat use became more restricted …

Aphid Natural Enemies And Biological Control, Ron Patterson, Ricardo Ramirez

All Current Publications

This fact sheet lists common arthropods of Utah that eat aphids. It will help identify those arthropods and will describe management practices that aid in their success. Many of these predators will eat other plant damaging insects in addition to aphids.

Observational Study Of Two Ex Situ North American River Otters (Lontra Canadensis), Julia Rifenberg

The Pegasus Review: UCF Undergraduate Research Journal

Zoos enable the ability to study how captive conditions impact the behaviors of animals. In this study, I observed two North American river otters housed at the Central Florida Zoo to evaluate behavioral changes after the male had been removed from the female for a month-long medical examination. The aim of this study was to 1) determine if mating behaviors were still occurring between the two river otters following the male’s removal and 2) to assess the welfare of the male and female river otters in captivity by observing their interactions and individual behaviors. Observed behaviors were compared to documented …

The Future Of Organic Insect Pest Management: Be A Better Entomologist Or Pay For Someone Who Is, David H. Headrick

Horticulture and Crop Science

Insect pest management in certified organic production systems presents considerable challenges for growers. The Federal National Organic Program (NOP) guidelines list acceptable tactics, but their effective use requires a considerable knowledgebase in entomology. The range of tactics allowed by the NOP are viewed as limiting by many growers and there are important elements missing from the list such as pest monitoring and identification. Educational programs must consider utilizing instructional methods and additional means of outreach that introduce new pest management tactics that are individualized, regionally appropriate and emphasize grower adoption and collaboration with local professionals. This review describes the challenges …

Japanese Quail (Coturnix Japonica) As A Novel Model To Study The Relationship Between The Avian Microbiome And Microbial Endocrinology-Based Host-Microbe Interactions, James Keane, Joshua M. Lyte, Julia Eckenberger, Nicholas Anthony, Sandip Shrestha, Daya Marasini, Karrie M. Daniels, Valentina Caputi, Annie M. Donoghue, Mark Lyte

Articles

Background

Microbial endocrinology, which is the study of neuroendocrine-based interkingdom signaling, provides a causal mechanistic framework for understanding the bi-directional crosstalk between the host and microbiome, especially as regards the effect of stress on health and disease. The importance of the cecal microbiome in avian health is well-recognized, yet little is understood regarding the mechanisms underpinning the avian host-microbiome relationship. Neuroendocrine plasticity of avian tissues that are focal points of host-microbiome interaction, such as the gut and lung, has likewise received limited attention. Avian in vivo models that enable the study of the neuroendocrine dynamic between host and microbiome are …

Parisitology Bio 331, Michael Cerbo

Library Impact Statements

No abstract provided.

Decreased Cortisol Among Hikers Who Preferentially Visit And Value Biodiverse Riparian Zones, Ellie Opdahl, Kathryn Demps, Julie A. Heath

Anthropology Faculty Publications and Presentations

While outdoor recreationists often report increases to their well-being for time spent in nature, the mechanisms through which local ecologies affect human health have been difficult to quantify, and thus to manage. We combine data from pre-post salivary cortisol measures, GPS tracks, visitor photos, and surveys from 88 hikers traversing several types of landscape within peri-urban public lands in southwest Idaho, USA. We find that time in biodiverse riparian areas and areas of perceived aesthetic value correlates with decreases in salivary cortisol and improved well-being for hikers. Wildlife sightings were not associated with changes in salivary cortisol, but were associated …

Reducing The Obesity Epidemic Globally, Kimberli Pepper

Global Sustainable Development Projects

The consumption of high fructose corn syrup (HFCS) has caused a global obesity epidemic that has several health implications such as type two diabetes, fatty liver disease, kidney failure, oxidative stress, insulin resistance, multiple types of cancer, and pathogenesis of cardiometabolic diseases (Johnson et al., 2013; Malik and Hu, 2015; Romieu et al., 2017; Softic et al., 2016). The prevalence of obesity in the United States was evaluated by the Center for Disease Control (CDC) and reported that USA was at 39.8 percent, which is a significant risk factor for the development of type two diabetes mellitus (T2DM) (Mejia and …

Will There Be Changes In Sexually Differentiated Behaviors In Mice Manipulated For The Sry Gene As They Mature Into Adultood?, Subin Joo

CMC Senior Theses

Sexually differentiated behavior has been shown to be affected by both genes and hormones. The discovery of the SRY gene, which codes for the development of testes, lead to the development of the Four Core Genotypes model of mice, and the separation of sex chromosomes and its resulting gonadal hormones. Using the FCG model, this study aims to look at the development of sexually differentiated behavior in mice, and track how it changes throughout their life. FCG mice will be divided into individual and social housing, and repeated experiments carried out to test their reaction to both intact female and …

Examining A Functional Interaction Between Chromatin Remodeler Chd1 And Histone H1 In D. Melanogaster, Breanna Kim

Scripps Senior Theses

Chromodomain-helicase-DNA-binding-protein-1 (CHD1) is a highly conserved ATP- dependent remodeling protein. It is localized to active genes and directs nucleosome spacing, while its loss has been linked to various human diseases, such as human prostate cancer. In Drosophila, CHD1 is important for fertility and wing development, and overexpression of CHD1 leads to severe wing vein defect phenotypes. The Linker Histone H1, which is known for maintaining heterochromatin and is associated with inactive genes, had been previously identified as a possible functional partner of CHD1, though the exact nature of their interaction is unclear. I undertook a genetic approach to examining the …

Lifelines Winter 2021, Southern Adventist University

Lifelines - Biology Department Newsletter

The Winter 2021 issue of Lifelines contains articles on Insights from the Professor, Alumni Spotlight, Students in Service, and Department Happenings.

Change In The Behaviors And Spatial Use Of Canada Lynx (Lynx Canadensis) Over Time At John Ball Zoo, Hailee Cederquist

Student Summer Scholars Manuscripts

Felines are popular attractions at zoos across the country, even more so when young animals are involved. As such caretakers strive to ensure that their animal’s needs are met, and individuals display healthy behaviors and activity levels in comparison to their wild counterparts (Mcphee & Carlstead, 2010). However, cats, being wide-ranging carnivores, are known to be prone to stereotypical behaviors which can be detrimental to an animal’s health (Clubb & Mason, 2003). At John Ball Zoo in Grand Rapids, Michigan, we observed the behaviors and spatial use of 3 Canada lynx (Lynx canadensis) during the summer of 2020; an adult …

Microsatellites And Their Association With Break Induced Replication, French J. Damewood Iv

Browse all Theses and Dissertations

To study microsatellites instability and their repair pathways a dual fluorescent (DF2) and selectable (ganciclovir sensitive/ thymidine kinase (TK) expressing) cell system was assayed using replication fork stalling agents hydroxyurea and telomestatin. These cell lines carried ectopically integrated microsatellites derived from the Dystrophia Myotonica Protein Kinase (DMPK) gene ((CTG)102 microsatellite), or an 88 bp polypurine/ polypyrimidine (Pu/Py) repeat from the PKD-1 locus, inserted into a FLP recombinase target site. These microsatellites form non-B DNA structures in -vivo and in-vitro causing replication fork stalling and double strand breaks. DF2 myc (CTG)102 -TK cells treated with hydroxyurea were assayed for mutagenesis of …

The Role Of Software Engineering In Bioinformatics, Brendan Sean Lawlor

Theses

This thesis proposes that by applying state-of-the-art software engineering tools, techniques and frameworks to currently recognised challenges in bioinformatics, improved outcomes can be attained in that field. It begins by decomposing software engineering into two categories, namely process and architecture, and choosing two key challenges in the practice of bioinformatics: reproducibility and scalability. The body of the thesis is an exploration of the intersection between these two software engineering categories and these two bioinformatics challenges. The question is asked: Can best practices in professional software engineering be applied to address key issues in the bioinformatics domain, creating positive outcomes? And …

Analyses Of Coyote (Canis Latrans) Consumption Of Anthropogenic Material And Dietary Composition In Urban And Non-Urban Habitats, Audrey A. Hayes

Browse all Theses and Dissertations

Coyotes are a generalist species that have adapted to nearly every terrestrial habitat in the United States. The species’ success is heavily attributed to their omnivorous diets and tolerance for environments that are regularly disturbed. Because the larger predator species that typically act as apex predators are sensitive to highly fragmented landscapes, the coyote is the functioning apex predator in many ecosystems where large predators, such as wolves, have been extirpated. The coyotes’ ecological role in urban ecosystems has received much attention in the last few decades as the species’ presence in cities and suburbs has increased, along with human-coyote …

Interleukin-2 Receptor Alpha Nuclear Localization Impacts Vascular Smooth Muscle Cell Function And Phenotype, Kristie Nhi Dinh

Browse all Theses and Dissertations

Atherosclerosis is responsible for 50% of all deaths in western society and is the main cause of cardiovascular diseases (Pahwa et al. 2020). Vascular smooth muscle cells (VSMC) play a vital role in the development of atherosclerotic plaques; this is due to their ability to proliferate and migrate in response to inflammation and damage to arteries’ inner linings. To further understand what causes these cells to proliferate and migrate, our lab has previously found that VSMC express all three subunits of the IL-2 receptor (IL-2R). Out of these three subunits, IL-2Rα appeared to change the most depending on the phenotype …

Microsatellites And Their Association With Break Induced Replication, French J. Damewood Iv

Browse all Theses and Dissertations

To study microsatellites instability and their repair pathways a dual fluorescent (DF2) and selectable (ganciclovir sensitive/ thymidine kinase (TK) expressing) cell system was assayed using replication fork stalling agents hydroxyurea and telomestatin. These cell lines carried ectopically integrated microsatellites derived from the Dystrophia Myotonica Protein Kinase (DMPK) gene ((CTG)102 microsatellite), or an 88 bp polypurine/ polypyrimidine (Pu/Py) repeat from the PKD-1 locus, inserted into a FLP recombinase target site. These microsatellites form non-B DNA structures in -vivo and in-vitro causing replication fork stalling and double strand breaks. DF2 myc (CTG)102 -TK cells treated with hydroxyurea were assayed for mutagenesis of …

Characterizing The Effects Of 14-3-3 Isoforms On Alpha-Synuclein Toxicity In A Yeast Model, Angela Marie Braunschweiger

Browse all Theses and Dissertations

The presynaptic protein alpha-synuclein encoded by SNCA is the primary component of Lewy bodies and Lewy neurites which are the histopathological hallmarks of Parkinson’s disease. While the etiology of Parkinson’s remains unclear, SNCA mutations and copy number variations are one of several genes linked to Parkinson’s. The family of highly conserved chaperone proteins 14-3-3 have been shown to co-aggregate and share regions of 40% homology with alpha-synuclein. Mitochondrial dysfunction also plays a role in Parkinson’s disease with abnormalities in mitochondrial respiration due to interference of complex I in the electron transport chain being found in Parkinson’s patients. Alpha-synuclein increases fragmentation …