Life Sciences Commons^™

Effects Of Air-Frying And Microwave Treatment On The Quality Of Pumpkin Seed Kernels, Zhang Gui-Hui, Ouyang Hui, Huang Yu, Yu Xiong-Wei, Li Shu-Gang

Food and Machinery

Objective: This study aimed to explore the effect of processing methods on the quality of pumpkin seed kernels. Methods: In this study, pumpkin seed kernels were chosen as the research object and the effects of air-frying (160 ℃, 0~7 min) and microwave treatment (700 W, 0~7 min) on the physical and chemical properties of proteins were investigated. Results: The experimental results showed that: after air-frying and microwave treatment, polyphenol, flavone, polysaccharide contents, as well as sensory scores all increased at the beginning, then decreased gradually, and reached the peak values when being treated by air-frying for 4 …

Study On The Process Of Α-Amylase Reduces The Content Of Rapidly Digestion Starch In Highland Barley, Zhang Hua, Song Xiao-Fan, Li Yan, Sun Kang-Na, Yuan Zhen-Zhen

Food and Machinery

Objective: This study aimed to help with improving and increasing the added value of highland barley. Methods: Back highland barley powder was used as raw material to prepare low content rapidly digestible starch by α-amylase. Highland barley powder with low content of fast digestible starch was prepared by α-amylase. The optimal technological conditions for reducing the content of fast digestible starch in highland barley were optimized by response surface test with the content of fast digestible starch as the index, and the hypoglycemic activity in vitro was evaluated by the inhibition rate of α-glucosidase and α-amylase. Results: …

Research Progress On Application Of Eggshell Membrane, Zhang Gai-Ping, Niu Ming-Fu, He Jiao

Food and Machinery

This review summarized the source, structural properties and applications of eggshell membrane(ESM)in various industries. The application limitation and future prospect of ESM were analyzed and prospected.

Cardiac Neural Crest And Cardiac Regeneration, Shannon Erhardt, Jun Wang

Faculty, Staff and Student Publications

Neural crest cells (NCCs) are a vertebrate-specific, multipotent stem cell population that have the ability to migrate and differentiate into various cell populations throughout the embryo during embryogenesis. The heart is a muscular and complex organ whose primary function is to pump blood and nutrients throughout the body. Mammalian hearts, such as those of humans, lose their regenerative ability shortly after birth. However, a few vertebrate species, such as zebrafish, have the ability to self-repair/regenerate after cardiac damage. Recent research has discovered the potential functional ability and contribution of cardiac NCCs to cardiac regeneration through the use of various vertebrate …

Clinical Significance Of Glycolytic Metabolic Activity In Hepatocellular Carcinoma, Joann Jung, Sowon Park, Yeonwoo Jang, Sung-Hwan Lee, Yun Seong Jeong, Sun Young Yim, Ju-Seog Lee

Faculty, Staff and Student Publications

High metabolic activity is a hallmark of cancers, including hepatocellular carcinoma (HCC). However, the molecular features of HCC with high metabolic activity contributing to clinical outcomes and the therapeutic implications of these characteristics are poorly understood. We aimed to define the features of HCC with high metabolic activity and uncover its association with response to current therapies. By integrating gene expression data from mouse liver tissues and tumor tissues from HCC patients (n = 1038), we uncovered three metabolically distinct HCC subtypes that differ in clinical outcomes and underlying molecular biology. The high metabolic subtype is characterized by poor …

Smokejumper Obituary: Rosenkrance, Lester Kenneth “Les” (Mccall 1961), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Smokejumper Obituary: Newton, Roger (Cave Junction 1951), National Smokejumper Association

Smokejumper Obituaries

No abstract provided.

Aa And Dha Are Decreased In Paediatric Ad/Hd And Inattention Is Ameliorated By Increased Plasma Dha, John J. Miklavcic, Ellen Ivity, Ian M. Macdonald, Liana Urichuk, Vera C. Mazurak, Christina Rinaldi, Michael T. Clandinin

Food Science Faculty Articles and Research

The purpose of this study was to assess long chain polyunsaturated fatty acid (LCPUFA) status in relation to socio-behavioral outcomes in children with Attention Deficit/Hyperactivity Disorder (AD/HD). In a case-control design, plasma phospholipid fatty acid content was assessed in children aged 5–12 years with AD/HD and in typically functioning children. Dietary intakes of LCPUFAs arachidonic acid (AA; 20:4n6) and docosahexaenoic acid (DHA; 22:6n3) were quantified using a four-day food record, polymorphisms were determined in FADS1 and FADS2, and socio-behavioral outcomes were assessed using the Conners 3 Parent Rating Scales in a cross section of children with AD/HD. Compared to …

Aspen Leaves As A "Chemical Landscape" For Fungal Endophyte Diversity - Can Nitrogen And Herbivory Shape The Community Composition In Controlled Conditions?, Johanna Witzell, Vicki Huizu Guo Decker, Marta Agostinelli, Carmen Romeralo Tapia, Michelle Cleary, Benedicte Riber Albrectsen

Aspen Bibliography

The endophytic microbiome may influence the ecological performance of plants, including forest trees. Various abiotic and biotic factors may shape the endophyte communities directly but also indirectly, by modifying the quality of host plants as a substrate. We hypothesized that potentially antifungal or fungistatic condensed tannins (CTs) would determine the quality of aspen (Populus tremula) leaves as a substrate for endophytic fungi. By subjecting the plants to nitrogen fertilization (N) or herbivory (H; leaf beetles) we aimed to change the internal “chemical landscape”, especially the CT levels, in aspen leaves. We expected that this would lead to changes in the …

Easy Calibration For Backpack And Canister (Handheld) Sprayers, Cody Zesiger, Kalen Taylor, Corey Ransom, Earl Creech, Matt Yost

All Current Publications

When applying pesticides, fertilizers, and other chemicals, the applicator should know the amount of chemical applied to the treated area. Calibration is a method an applicator can use to measure and set the application rate. If sprayers are not properly calibrated, it can result in over or under application of chemicals, causing damage, reduced pest control, and potential safety concerns. Making the effort to properly mix chemicals and calibrate sprayers can save money and increase treatment effectiveness. This fact sheet provides simple guidelines for calibrating backpack and canister sprayers.

Easy Calibration For Boom Sprayers, Cody Zesiger, Kalen Taylor, Corey Ransom, Earl Creech, Matt Yost

All Current Publications

Calibrating spray equipment is an important first step when applying pesticides, fertilizers, and other chemicals. If nozzles are not properly calibrated, it can result in over or under application of chemicals, causing crop damage, reduced pest control, and potential safety concerns. Making the effort to properly mix chemicals and calibrate sprayers can save money and headaches in the long run. This fact sheet provides simple guidelines for calibrating boom sprayers.

Novel Therapeutic Nutrients Molecules That Protect Against Zika Virus Infection With A Special Note On Palmitoleate, Philma Glora Muthuraj, Chandan Krishnamoorthy, Ann Anderson-Berry, Corrine K. Hanson, Sathish Kumar Natarajan

Department of Nutrition and Health Sciences: Faculty Publications

Zika virus (ZIKV) is a Flavivirus from the Flaviviridae family and a positive-sense single strand RNA virus. ZIKV infection can cause a mild infection to the mother but can be vertically transmitted to the developing fetus, causing congenital anomalies. The prevalence of ZIKV infections was relatively insignificant with sporadic outbreaks in the Asian and African continents until 2006. However, recent epidemic in the Caribbean showed significant increased incidence of Congenital Zika Syndrome. ZIKV infection results in placental pathology which plays a crucial role in disease transmission from mother to fetus. Currently, there is no Food and Drug Administration (FDA) approved …

Natural Selection Of Immune And Metabolic Genes Associated With Health In Two Lowland Bolivian Populations, Amanda J. Lea, Angela Garcia, Jesusa Arevalo, Julien F. Ayroles, Kenneth Buetow, Steve W. Cole, Daniel Eid Rodriguez, Maguin Gutierrez, Heather M. Highland, Paul L. Hooper, Anne Justice, Thomas Kraft, Kari E. North, Jonathan Stieglitz, Hillard Kaplan, Benjamin C. Trumble, Michael Gurven

ESI Publications

A growing body of work has addressed human adaptations to diverse environments using genomic data, but few studies have connected putatively selected alleles to phenotypes, much less among underrepresented populations such as Amerindians. Studies of natural selection and genotype–phenotype relationships in underrepresented populations hold potential to uncover previously undescribed loci underlying evolutionarily and biomedically relevant traits. Here, we worked with the Tsimane and the Moseten, two Amerindian populations inhabiting the Bolivian lowlands. We focused most intensively on the Tsimane, because long-term anthropological work with this group has shown that they have a high burden of both macro and microparasites, as …

Do The Culturable Microbial Groups Present In Cutaway Bogs Change According To Temporal Variation? Pilot Study Based On The Midlands In The Republic Of Ireland, Gouri Atapattu, Tara Battersby, Michelle Giltrap, Furong Tian Nanolab Research Centre, Focas Research Institute, Technological University Dublin

Articles

Cutaway peatlands in the midlands of the Republic of Ireland are rarely the focus of scientific studies. The soil quality and related microenvironment have been severely impacted by peat extraction. Returning them to a ‘near-natural state’ would require greater insights into this ecological niche. The current research took the initiative to study the microbiology of vast cutaway sites in the midlands of Ireland. Peat was collected over two seasons in January, February and April. Homogenised peat was aseptically cultured on a range of specific and non-specific culture media. Microbial enumeration, Gram staining and other microscopic observations of morphologically distinct microorganisms …

Taking Action: Turning Evolutionary Theory Into Preventive Policies, Orsolya Molnár, Marina Knickel, Christine Marizzi

MANTER: Journal of Parasite Biodiversity

The emerging infectious disease (EID) crisis has been challenging global health security for decades, dealing substantial damage to all socioeconomic landscapes. Control measures have failed to prevent or even mitigate damages from an accelerating wave of EIDs, leading to the emergence and devastation caused by the COVID-19 pandemic. In the wake of the pandemic, we must critically review our public health policies and approaches. Current health security measures are based on the evolutionary theorem of host-parasite coevolution, which falsely deems EIDs as rare and unpredictable. The DAMA protocol (Document, Assess, Monitor, Act) is nested in a novel evolutionary framework that …

Comparison Of Machine-Learning And Deep-Learning Methods For The Prediction Of Osteoradionecrosis Resulting From Head And Neck Cancer Radiation Therapy, Brandon Reber, Lisanne Van Dijk, Brian Anderson, Abdallah Sherif Radwan Mohamed, Clifton Fuller, Stephen Lai, Kristy Brock

Faculty, Staff and Student Publications

PURPOSE: Deep-learning (DL) techniques have been successful in disease-prediction tasks and could improve the prediction of mandible osteoradionecrosis (ORN) resulting from head and neck cancer (HNC) radiation therapy. In this study, we retrospectively compared the performance of DL algorithms and traditional machine-learning (ML) techniques to predict mandible ORN binary outcome in an extensive cohort of patients with HNC.

METHODS AND MATERIALS: Patients who received HNC radiation therapy at the University of Texas MD Anderson Cancer Center from 2005 to 2015 were identified for the ML (n = 1259) and DL (n = 1236) studies. The subjects were followed for ORN …

A Report Of Intraguild Predation By Orthochirus Sp. On Hottentotta Tamulus (Scorpiones: Buthidae) In Maharashtra, India, Mihir Joshi, Shubhankar Deshpande

Euscorpius

We report an event of intraguild predation by Orthochirus sp. feeding on a juvenile individual of Hottentotta tamulus (Fabricius,1798) from Maharashtra, India. This is the first report of intraguild predation among Indian scorpions.

New Worm On The Block: Planarians In (Neuro)Toxicology, Danielle Ireland, Eva-Maria S. Collins

Biology Faculty Works

Traditional mammalian testing is too time- and cost-intensive to keep up with the large number of environmental chemicals needing assessment. This has led to a dearth of information about the potential adverse effects of these chemicals, especially on the developing brain. Thus, there is an urgent need for rapid and cost-effective neurotoxicity and developmental neurotoxicity testing. Because of the complexity of the brain, metabolically competent organismal models are necessary to understand the effects of chemicals on nervous system development and function on a systems level. In this overview, we showcase asexual freshwater planarians as an alternative invertebrate (“non-animal”) organismal model …

Multipolymer Microsphere Delivery Of Sars-Cov-2 Antigens, Farah Shahjin, Milankumar Patel, Jatin Machhi, Jacob D. Cohen, Mohammad Ullah Nayan, Pravin Yeapuri, Chen Zhang, Emiko Waight, Mahmudul Hasan, Mai Mohamed Abdelmoaty, Prasanta K. Dash, You Zhou, Irene Andreu, Howard E. Gendelman, Bhavesh D. Kevadiya

Nebraska Center for Biotechnology: Faculty and Staff Publications

Effective antigen delivery facilitates antiviral vaccine success defined by effective immune protective re- sponses against viral exposures. To improve severe acute respiratory syndrome coronavirus-2 (SARS-CoV- 2) antigen delivery, a controlled biodegradable, stable, biocompatible, and nontoxic polymeric micro- sphere system was developed for chemically inactivated viral proteins. SARS-CoV-2 proteins encapsulated in polymeric microspheres induced robust antiviral immunity. The viral antigen-loaded microsphere sys- tem can preclude the need for repeat administrations, highlighting its potential as an effective vaccine.

Kidney Proximal Tubule Glut2-More Than Meets The Eye, Majdoleen Ahmad, Ifat Abramovich, Bella Agranovich, Alina Nemirovski, Eyal Gottlieb, Liad Hinden, Joseph Tam

Faculty, Staff and Student Publications

Tubulopathy plays a central role in the pathophysiology of diabetic kidney disease (DKD). Under diabetic conditions, the kidney proximal tubule cells (KPTCs) are exposed to an extensive amount of nutrients, most notably glucose; these nutrients deteriorate KPTCs function and promote the development and progression of DKD. Recently, the facilitative glucose transporter 2 (GLUT2) in KPTCs has emerged as a central regulator in the pathogenesis of DKD. This has been demonstrated by identifying its specific role in enhancing glucose reabsorption and glucotoxicity, and by deciphering its effect in regulating the expression of the sodium-glucose transporter 2 (SGLT2) in KPTCs. Moreover, reduction/deletion …

Anti-Cancer Mechanisms Of Action Of Therapeutic Alternating Electric Fields (Tumor Treating Fields [Ttfields]), Shadi Shams, Chirag B Patel

Faculty, Staff and Student Publications

Despite improved survival outcomes across many cancer types, the prognosis remains grim for certain solid organ cancers including glioblastoma and pancreatic cancer. Invariably in these cancers, the control achieved by time-limited interventions such as traditional surgical resection, radiation therapy, and chemotherapy is short-lived. A new form of anti-cancer therapy called therapeutic alternating electric fields (AEFs) or tumor treating fields (TTFields) has been shown, either by itself or in combination with chemotherapy, to have anti-cancer effects that translate to improved survival outcomes in patients. Although the pre-clinical and clinical data are promising, the mechanisms of TTFields are not fully elucidated. Many …

The Genus Barbaracurus In Saudi Arabia (Scorpiones: Buthidae), With Description Of A New Species, František Kovařík, Graeme Lowe, František Šťáhlavský, Pavel Just

Euscorpius

The genus Barbaracurus (Scorpiones: Buthidae) is recorded for the first time from Saudi Arabia. B. yemenensis Kovařík et al., 2018 was found in the extreme southwest of the country, near its border with Yemen. The diagnosis of the species is emended based on the finding of adult males and a large adult female. The proximal margins of the pedipalp fingers of male B. yemenensis are strongly undulate, leaving a gap with the fingers closed. This character differentiates it from all other species of Barbaracurus in the Arabian Peninsula. A second species, B. kabateki sp. n. from Saudi Arabia is described …

Apoptotic Effect Of Bortezomib On Pancreatic Islet Cells In Stz-Induced Diabetic Rats, Çiğdem Ekin, Neslihan Tekin Karacaer, Mehtap Tarhan Karaoğlan, Ibrahim Örün, Kamile Öztürk

Makara Journal of Health Research

Background: This study aimed to investigate the possible apoptotic role of bortezomib (BMZ) on pancreatic islets of streptozotocin (STZ)-induced diabetic rats.

Methods: Sprague-Dawley rats were divided into groups that were administered BMZ alone or in combination with STZ. To evaluate the effect of BMZ on the development of diabetes, blood glucose levels were measured regularly in the animals. Islet cell viability was determined by staining the islets with fluorescein diacetate and propidium iodide. Expression of the Bcl-2 and bax genes was determined in islet cells by quantitative real-time polymerase chain reaction.

Results: Administering STZ-induced hyperglycemia in the …

Mechanical And Thermal Load Effect On Piston Crown Of A Biogas Engine: A Simulation Approach, Truc Nguyen The, Anh Duc Tran, Cam Van Nguyen, Khac Tung Nguyen, Dinh Long Hoang, Xuan Phong Trinh, Nguyen Duc Khanh

ASEAN Journal on Science and Technology for Development

This paper presents the study results on stress and deformation of the piston crown of a biogas engine converted from a conventional diesel engine using dedicated software. The original diesel engine was modified to reduce the compression ratio to suit biogas fuel. The original engine's combustion chamber and compression ratio were changed by modifying the piston crown to a heron type. The parameters of in-cylinder pressure and temperature were determined by the thermodynamic simulation software AVL Boost. Research results show that the in-cylinder pressure decreased compared to diesel when using biogas fuel, but the temperature increased. The infinite element method-based …

Mechanical Ventilation In Patients With Cardiogenic Pulmonary Edema: A Sub-Analysis Of The Lung Safe Study, Laura Amado-Rodríguez, Raquel Rodríguez-Garcia, Giacomo Bellani, Tài Pham, Eddy Fan, Fabiana Madotto, John G Laffey, Guillermo M Albaiceta, Lung Safe Investigators

Faculty, Staff and Student Publications

BACKGROUND: Patients with acute respiratory failure caused by cardiogenic pulmonary edema (CPE) may require mechanical ventilation that can cause further lung damage. Our aim was to determine the impact of ventilatory settings on CPE mortality.

METHODS: Patients from the LUNG SAFE cohort, a multicenter prospective cohort study of patients undergoing mechanical ventilation, were studied. Relationships between ventilatory parameters and outcomes (ICU discharge/hospital mortality) were assessed using latent mixture analysis and a marginal structural model.

RESULTS: From 4499 patients, 391 meeting CPE criteria (median age 70 [interquartile range 59-78], 40% female) were included. ICU and hospital mortality were 34% and 40%, …

Suitability Of Current Single-Cylinder Diesel Engines Available In Indonesia With New Indonesian National Standard (Sni 119:2020), Sukra Kurnia Fajar Adhi, Setiapraja Hari, Soewono Respatya Teguh, Sumartono Hari

ASEAN Journal on Science and Technology for Development

Diesel engines have been utilized for various purposes in Indonesia. Diesel engine manufacturers have developed designs and competed with each other to win the market in Indonesia. Nationally and internationally recognized standards are required to ensure the quality of products for Indonesia and the international market. The Indonesian National Standard (SNI) 119 is one of the recognized standards for single-cylinder diesel engine in Indonesia. Compared with the previous SNI 0119:2012, SNI 119:2020 has revised the limits of some parameters. This study evaluated the passing data of SNI test results from 2015 to 2020 and then analyzed the distribution of engines …

Analysis Of Surface Water Availability To Meet Agricultural Water Demands In Kediri Regency, Indonesia, Sekaranom Andung Bayu, Purnama I.G. Setyawan, Cahyadi Ahmad, Andika Neil, Febriarta Erik, Nurjani Emilya, Firmansyah Anugrah Jorgi, Maghfiroh, Larasati Chafda, Septyo Novanna Dwi

ASEAN Journal on Science and Technology for Development

This study aims to analyze the potential of surface water to meet agricultural water needs in Kediri Regency, Indonesia. Data from government agencies (i.e., Indonesian Bureau of Meteorology, Climatology, and Geophysics and Kediri Agriculture Office) and fieldwork were analyzed to achieve the research objectives. The data obtained consisted of rainfall, temperature, infiltration capacity, soil texture, root depth, and agricultural land area. The potential of surface water resources was calculated by using the Thornthwaite–Mather water balance method. The water balance results were compared with agricultural water demands, which were calculated on the basis of the area of agricultural land and type …

Manuka Honey Reduces The Virulence Of Pectobacterium Brasiliense By Suppressing Genes That Encode Plant Cell Wall-Degrading Enzymes, Ava Sheila, Subandiyah Siti, Rohman Muhammad Saifur, Ogawa Naoto, Joko Tri

ASEAN Journal on Science and Technology for Development

The primary virulence of soft rot pectobacteria, including Pectobacterium brasiliense, is mainly determined by the massive production of plant cell wall-degrading enzymes (PCWDEs), which promote plant tissue maceration in many crops. The antibiotic treatment to treat bacterial soft rot causes environmental problems and potentially affects resistance. Antibiotic resistance is driving interest in antimicrobial treatments, and no organism has been reported to have acquired resistance to honey. However, the use of honey as a therapeutic agent for plant bacterial pathogens has rarely been studied. Therefore, this study was undertaken to determine the in vitro effect of Manuka honey against P. brasiliense …

A Systematic Review Of The Effects Of Meditative And Mindful Walking On Mental And Cardiovascular Health, Dustin W. Davis, Bryson Carrier, Kyle Cruz, Brenna Barrios, Merrill Russen Landers, James W. Navalta

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 1692-1734, 2022. Meditative and mindful exercise are types of physical exercise during which people pay attention, on purpose, to each new present moment without judging their experience. The goal is to apply an accepting awareness of the environment, bodily sensations, thoughts, and emotions without labeling them (e.g., good or bad). The literature centers on qigong, tai chi, and yoga, which are types of mindful exercise that improve mental and cardiovascular health. It is unclear if meditative and mindful walking also improve these health domains. To the authors’ knowledge, this question has not been addressed …

Exome Array Analysis Of 9721 Ischemic Stroke Cases From The Sign Consortium, Huichun Xu, Kevin Nguyen, Brady J Gaynor, Hua Ling, Wei Zhao, Patrick F Mcardle, Timothy D O'Connor, O Colin Stine, Kathleen A Ryan, Megan Lynch, Jennifer A Smith, Jessica D Faul, Yao Hu, Jeffrey W Haessler, Myriam Fornage, Charles Kooperberg, On Behalf Of The Trans-Omics For Precision Medicine Topmed Stroke Working Group, James A Perry, Charles C Hong, John W Cole, Elizabeth Pugh, Kimberly Doheny, Sharon L R Kardia, David R Weir, Steven J Kittner, Braxton D Mitchell, Sign Consortium

Faculty, Staff and Student Publications

Recent genome wide association studies have identified 89 common genetic variants robustly associated with ischemic stroke and primarily located in non-coding regions. To evaluate the contribution of coding variants, which are mostly rare, we performed an exome array analysis on 106,101 SNPs for 9721 ischemic stroke cases from the SiGN Consortium, and 12,345 subjects with no history of stroke from the Health Retirement Study and SiGN consortium. We identified 15 coding variants significantly associated with all ischemic stroke at array-wide threshold (i.e., p < 4.7 × 10-7), including two common SNPs in ABO that have previously been associated with stroke. Twelve of the remaining 13 variants were extremely rare …