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Articles 1 - 12 of 12
Full-Text Articles in Life Sciences
Ankyrin Dependent Mitochondrial Function And Bioenergetics In The Heart, Janani Subramaniam, Janani Subramaniam
Ankyrin Dependent Mitochondrial Function And Bioenergetics In The Heart, Janani Subramaniam, Janani Subramaniam
Dissertations & Theses (Open Access)
ANK2 mutations in patients are associated with numerous arrhythmias, cardiomyopathies, and other heart defects. In the heart, AnkB, the protein encoded by ANK2, clusters relevant ion channels and cell adhesion molecules in several important domains; however, its role at Mitochondria Associated ER/SR Membranes (MAMs) has yet to be investigated. MAMs are crucial to mitochondrial function and metabolism and are signaling hubs implicated in various cardiac pathologies. Among several functions, these sites mediate the direct transfer of calcium from the ER/SR to the mitochondria to modulate ATP synthesis. Given that mitochondrial function and energy production are paramount to cardiovascular heath, …
Recent Advancements On Calcium And Phosphorus Recommendations In Broilers, Justina Caldas, Marcelo Silva
Recent Advancements On Calcium And Phosphorus Recommendations In Broilers, Justina Caldas, Marcelo Silva
Proceedings of the Arkansas Nutrition Conference
Calcium and phosphorus have been recognized essential nutrients in chickens since 1950’s (Lesson & Summers, 2001) playing important roles in bone development, among other functions. Calcium is assumed an inexpensive nutrient in animal least cost formulation while phosphorus is considered expensive and scant. The actual economic impact comes from the influence of calcium on phosphorus requirements, changes in phosphorus digestibility, buffer capacity, gut health, trace mineral absorption, fat digestibility, welfare traits, etc. Both minerals have important interactions to be considered during formulation. Few changes have been made over the past 20 years to calcium and phosphorus recommendations because these values …
Limestone Solubility: What Can You Do About It?, Wenting Li, Katie Hilton, Franco Mussini, Janet Remus
Limestone Solubility: What Can You Do About It?, Wenting Li, Katie Hilton, Franco Mussini, Janet Remus
Proceedings of the Arkansas Nutrition Conference
Calcium (Ca) is essential for bone development mineralisation, as well as for eggshell formation, muscle and neural functions. Depending on the type of diets (veggie vs. non-veggie), species (turkey, chicken, duck), and age of animal (young vs. adult), limestone can contribute up to 95% total Ca in the final diet, with more Ca from limestone for younger animals with veggie diet. Despite the significant contribution of limestone to total diet Ca levels, the bioavailability variation of limestone Ca is rarely considered. Phosphorus (P) is a limited resource and is the third most costly ingredient in poultry …
Computational Investigation Of Calmodulin Photocontrol With The Help Of An Azobenzene Derivative, Jeremy Wells
Computational Investigation Of Calmodulin Photocontrol With The Help Of An Azobenzene Derivative, Jeremy Wells
Undergraduate Honors Theses
The ability to control the activity and binding capability of enzymes in a reversible manner offers tremendous control over biological processes. Photocontrol, in particular, is promising in that electromagnetic radiation can be fine-tuned in terms of its strength, location, and duration. Photosensitive compounds, such as the azobenzene family, experience an isomerization at certain wavelengths, and attaching these compounds to enzymes has the potential to alter their structure and activity. Calmodulin (CaM) is a Ca2+ -sensitive signaling protein that has the ability to affect several downstream processes in eukaryotes and is an excellent target for photocontrol due to its small size …
Severe Hypoxia Up-Regulates Gluconeogenesis In Daphnia, Morad C. Malek
Severe Hypoxia Up-Regulates Gluconeogenesis In Daphnia, Morad C. Malek
Undergraduate Honors Theses
Hypoxia is a significant low oxygen state that has complex and diverse impacts on organisms. In aerobes, various adaptive responses to hypoxia are observed that vary depending on the level of oxygen depletion and previous adaptation, hence the continued attention to hypoxia as an important abiotic stressor. Adaptive responses to hypoxia are primarily governed by the hypoxia-inducible factors (HIFs), which activate downstream genetic pathways responsible for oxygen transport and metabolic plasticity. In aquatic habitats, oxygen availability can vary greatly over time and space. Therefore, aquatic organisms’ adaptation to hypoxia is likely pervasive, especially in genotypes originating from waterbodies prone to …
Free-Enterprise Farming On Grasslands In Central Nsw, Australia, Des Green, Stuart Green, Ted Wolfe, Jo Richardson, Rob Eccles
Free-Enterprise Farming On Grasslands In Central Nsw, Australia, Des Green, Stuart Green, Ted Wolfe, Jo Richardson, Rob Eccles
IGC Proceedings (1997-2023)
A pathway is described in developing and improving the pastures on family-owned sheep and beef properties at sites near Blayney in central NSW. Initially, the twin approach of sowing perennial grasses, predominantly phalaris (Phalaris aquatica) with subterranean clover (Trifolium subterraneum) plus the recommended addition of superphosphate fertiliser, was closely followed but within a decade ill-thrift in pastures and livestock occurred. Once the core problem of soil acidity was recognised, steps were taken to overcome this constraint with applications of lime. However, an additional modification involving the application of gypsum with lime had to be sorted out …
Calcium-Mediated Induction Of Vibrio Fischeri Es114 Biofilms, Katia Elizabeth Semenchuk
Calcium-Mediated Induction Of Vibrio Fischeri Es114 Biofilms, Katia Elizabeth Semenchuk
Master's Theses
Vibrio fischeri bacteria form biofilms that facilitate symbiotic colonization of the Hawaiian bobtail squid, Euprymna scolopes. These host-associated biofilms require production of the SYP polysaccharide. However, it has been difficult to observe robust biofilm formation in vitro in a laboratory setting using wild-type strain ES114; instead, most work investigating syp-dependent biofilm formation has relied on genetically altered strains. Guided by recent findings that increasing calcium induces c-di-GMP (Tischler et al., 2021), a molecule known in other systems to promote biofilm formation, the question was posed as to whether high levels of calcium alone could promote syp-dependent biofilm formation by ES114. …
Development Of Fluorescence Based Approaches To Understand Astrocyte Biology In The Context Of Nicotine And Nicotinic Receptor Activity, Surya P. Aryal
Development Of Fluorescence Based Approaches To Understand Astrocyte Biology In The Context Of Nicotine And Nicotinic Receptor Activity, Surya P. Aryal
Theses and Dissertations--Chemistry
Smoking and tobacco use (STU) is a major global health problem and worldwide more than six million people die due to tobacco related diseases each year. Although majority of smokers try to quit smoking several times in their life, traditional therapeutic approaches, which focus only on neuronal cells, have a very low success rate. Understanding the effect of nicotine on glial cells, synaptic communication and blood vasculature in the brain can provide further insights on the neurobiology of substance abuse and can potentially help to design better therapeutic approaches. Glial cells are non-excitable cells in the brain which do not …
The Impact Of Dietary Analyzed Calcium To Phosphorus Ratios And Standardized Total Tract Digestible Phosphorus To Net Energy Ratios On Growth Performance, Bone, And Carcass Characteristics Of Pigs, Hadley R. Williams, Mike D. Tokach, Jason C. Woodworth, Joel M. Derouchey, Robert D. Goodband, Jordan T. Gebhardt, Carine M. Vier, Ning Lu, Ron Navales, Matthew Spindler, Uislei Orlando, Luis Zaragoza, Alyssa M. Betlach
The Impact Of Dietary Analyzed Calcium To Phosphorus Ratios And Standardized Total Tract Digestible Phosphorus To Net Energy Ratios On Growth Performance, Bone, And Carcass Characteristics Of Pigs, Hadley R. Williams, Mike D. Tokach, Jason C. Woodworth, Joel M. Derouchey, Robert D. Goodband, Jordan T. Gebhardt, Carine M. Vier, Ning Lu, Ron Navales, Matthew Spindler, Uislei Orlando, Luis Zaragoza, Alyssa M. Betlach
Kansas Agricultural Experiment Station Research Reports
A total of 2,184 pigs (PIC 337 × 1050; initially 27.3 lb) were used to evaluate the effects of feeding varying analyzed calcium to phosphorus (Ca:P) ratios at two levels of standardized total tract digestible (STTD) P:NE. Pens of pigs (26 pigs per pen) were assigned to 6 dietary treatments in a randomized complete block design with 14 pens per treatment. Diets consisted of two levels of STTD P:NE, including the PIC recommendation (1.8, 1.62, 1.43, 1.25, 1.10, and 0.99 g STTD P/Mcal NE from 25 to 50, 50 to 90, 90 to 130, 130 to 180, 180 to 230, …
Primary Cilia Display A Non-Uniform Response To Intracellular Calcium Release, Hannah R. Fisher
Primary Cilia Display A Non-Uniform Response To Intracellular Calcium Release, Hannah R. Fisher
WWU Graduate School Collection
Cilia are microtubule-based organelles that project from the surface of individual cells. When cilia are formed, they are nucleated from centrioles that are known as basal bodies. Microtubules elongating from the basal body give rise to the axoneme of the cilium, which gives cilia their rod-like structure. The axoneme is surrounded by a specialized plasma membrane that is unique, but continuous with the plasma membrane that surrounds the rest of the cell. The ciliary membrane is enriched with ion channels and membrane-bound proteins that are essential for cilia function. Interestingly, the cilium maintains a distinct environment from the rest of …
Effects Of Vitamin D Administration At The Beginning Of Lactation In Dairy Cows Oninflammatory Response And Liver Metabolism, Feyyaz Kaya, Hasan Batmaz
Effects Of Vitamin D Administration At The Beginning Of Lactation In Dairy Cows Oninflammatory Response And Liver Metabolism, Feyyaz Kaya, Hasan Batmaz
Turkish Journal of Veterinary & Animal Sciences
This study aimed to investigate the effect of vitamin D administered 24 h after calving of dairy cows on calcium-phosphorus metabolism, carbohydrate, lipid and liver metabolism, and inflammatory response. Twenty multiparous Holstein cows were randomly assigned to the experimental (EG) and control group (CG). The EG received 5,000,000 IU vitamin D3 (5 mL) 24 h after parturition intramuscularly, whereas the CG group received 5 mL of 0.9% NaCl. Blood samples were taken 24 h after parturition before treatments and at the 3rd, 7th, 14th, and 28th days of lactation. Serum NEFA, BHBA, haptoglobin, serum amyloid A (SAA), ceruloplasmin, calcium, phosphorus, …
Effects Of Dietary Calcium, Phosphorus And Microbial Phytase On Intestinal Morphologyin Laying Hens, Sabi̇re Güler, Ender Deni̇z Asmaz, Nuray Varol Kayapunar, İhsan İşbi̇li̇r, Şeri̇fe Şule Cengi̇z, Derya Yeşi̇lbağ, Ahmet Batuhan Şanli, Eyüp Eren Gültepe
Effects Of Dietary Calcium, Phosphorus And Microbial Phytase On Intestinal Morphologyin Laying Hens, Sabi̇re Güler, Ender Deni̇z Asmaz, Nuray Varol Kayapunar, İhsan İşbi̇li̇r, Şeri̇fe Şule Cengi̇z, Derya Yeşi̇lbağ, Ahmet Batuhan Şanli, Eyüp Eren Gültepe
Turkish Journal of Veterinary & Animal Sciences
Different challenges are being applied in the poultry industry in order to protect animal health and to increase immunity and production. The supplementation of microbial phytase is essential in terms of both reducing the inorganic phytase rate and contributing to the absorption of other minerals. In this study, a newly isolated microbial phytase was added at different concentrations to the diet together with calcium (Ca$^{2+}$) and available phosphorus (AP), and the effects of this supplementation on intestinal absorption capacity and Ca$^{2+}$ binding capacity were investigated via morphological measurements and immunohistochemical examination of the duodenum and ileum. For this purpose, 90 …