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The Influence Of Tas2r38 Bitter Taste Gene Polymorphisms On Obesity Risk In Three Racially Diverse Groups, Chaowanee Chupeerach, Pradtana Tapanee, Nattira On-Nom, Piya Temviriyanukul, Boonrat Chantong, Nicole Reeder, Grace A. Adegoye, Terezie Tolar-Peterson
The Influence Of Tas2r38 Bitter Taste Gene Polymorphisms On Obesity Risk In Three Racially Diverse Groups, Chaowanee Chupeerach, Pradtana Tapanee, Nattira On-Nom, Piya Temviriyanukul, Boonrat Chantong, Nicole Reeder, Grace A. Adegoye, Terezie Tolar-Peterson
BioMedicine
Objectives: Bitter taste perception affects food preference, eating behavior, and nutrient intake. The purpose of this study was to investigate the contribution of bitter taste gene polymorphisms to body fatness as measured by percentage of body fat.
Method: Three common single nucleotide polymorphisms (SNPs) of the TAS2R38 gene which result in amino acid changes in the protein (A49P, V262A, and I296V), were studied in three racially diverse groups: European Americans n=313, African Americans n=109, and Asians n=234.
Results: The allele frequencies of the three SNPs were similar to previous studies. The rare haplotypes, AAI and AAV, were found in high …