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Full-Text Articles in Life Sciences
Effects Of Catharanthine On Dopamine Release In The Nucleus Accumbens And Ethanol Consumption, Emily Baldwin
Effects Of Catharanthine On Dopamine Release In The Nucleus Accumbens And Ethanol Consumption, Emily Baldwin
Undergraduate Honors Theses
This thesis discusses the history of catharanthine and related compounds, and their potential anti-addictive properties. Current research is exploring possible mechanisms of these properties. Past studies have found catharanthine has effects on neurons that project to the mesocorticolimbic system, an area implicated in addiction. We have seen that catharanthine decreases evoked dopamine (DA) release but increases basal DA release. This is the first study to investigate catharanthine’s effect on DA transmission in vivo. Using microdialysis, we determined the effect of catharanthine on DA in the nucleus accumbens of the striatum. This study determines the effect of different doses of …
Facing Fears When Fearing Faces: Binocular Rivalry Perceptual Alternation And Approach-Avoidance In College-Aged Women With Autistic Traits And A History Of Adverse Experiences, Sarah Kamhout
Undergraduate Honors Theses
Women with Autism Spectrum Conditions (ASCs) may be more likely to experience symptoms of trauma exposure due to greater likelihood of facing adverse childhood experiences (ACEs). In order to gain a better understanding of the neural mechanisms involved with ASC and PTSD in women who experience difficulty with social interactions, I examined the ability of two vision tasks-- Binocular Rivalry Perceptual Alternation (BR) and Visual Approach/Avoidance by the Self Task (VAAST)-- to predict symptoms of both conditions as well as differentiate between them. I also examined differences in response to neutral or emotional (angry or fearful) faces under both paradigms. …
Preventing Alzheimer's: Effects Of Second Language Acquisition In Older Populations, Joshua Rhead
Preventing Alzheimer's: Effects Of Second Language Acquisition In Older Populations, Joshua Rhead
Undergraduate Honors Theses
Alzheimer’s disease continues to be a problem that medicine has few answers for. As a result, much research has been focused on finding a cure as well as interventions to help prevent the onset of the disease. One such intervention that has been proposed is to improve the brain’s efficiency and connectivity. A controversial method of achieving these results is through second language acquisition. Many provide evidence for or against the benefits of this intervention, but much remains unclear. Most of these studies focus on cognitive function and functional connectivity in language areas, but the default mode network, which is …