Life Sciences Commons^™

Osteopontin Facilitates West Nile Virus Neuroinvasion Via Neutrophil “Trojan Horse” Transport, Amber M. Paul, Dhiraj Acharya, Laurel Duty, E. Ashley Thompson, Linda Le, Dobrivoje S. Stokic, A. Arturo Leis, Fengwei Bai

Publications

West Nile virus (WNV) can cause severe human neurological diseases including encephalitis and meningitis. The mechanisms by which WNV enters the central nervous system (CNS) and host factors that are involved in WNV neuroinvasion are not completely understood. The proinflammatory chemokine osteopontin (OPN) is induced in multiple neuroinflammatory diseases and is responsible for leukocyte recruitment to sites of its expression. In this study, we found that WNV infection induced OPN expression in both human and mouse cells. Interestingly, WNV-infected OPN deficient (Opn−/−) mice exhibited a higher survival rate (70%) than wild type (WT) control mice (30%), suggesting OPN plays a …

Undergraduate Research On General Aviation Hypoxia: A Student's Perspective, Timothy B. Holt, Jacqueline Luedtke, Claire G. Schindler

Publications

The problem this study addresses is the uncertainty of the common circumstances that general aviation pilots find themselves in that create a hypoxic state, as well as whether or not that pilot reported the occurrence to the proper establishments. The results of this study showed not only those that were impacted the greatest by hypoxia, but also a caring concern for reporting these events. The key elements for this research were:

• Level of flying experience that encountered hypoxia

• Reporting statistics

• Reasons for not reporting the event

• Suggestions for bettering flight physiology training

Repository Review: Nasa Pubspace, Laura Pope Robbins

Publications

Laura Pope Robbins is an advisor for The Charleston Advisor, and the review below is included in Scholarly Commons with the permission of the publisher.

PubSpace is a repository of full-text peer-reviewed articles resulting from NASA-funded research going back to 1961. The National Center for Biotechnology Information has integrated PubSpace into PubMed Central, a freely available repository of medical research. Using an established, stable, government-hosted platform for PubSpace seems to make sense. However, the lack of clear branding, an uneven application of phrase searching, and a missing thesaurus of NASA terminology highlights that this integration may not be the best.

Information Technology Approaches To Forest Management, Mary Snow, Richard Snow

Publications

The majority of the world’s forests occur where there is a dry season long enough to affect a seasonal change in the forest community. The seasonal forest may include evergreen, semi-deciduous, deciduous trees, or some combination of these. Local differences in soil or other site characteristics often determine which community persists. Since the seasonal forests exist where there is seasonal precipitation, the character of the forest is closely associated with the length of the rainy season. As the length of the rainy season decreases, the density of the canopy decreases. If the global climate system warms and prolonged drought gives …

Impact Of Aquaculture On The Livelihoods And Food Security Of Rural Communities, Rajee Olaganathan, Alicia Tang Kar Mun

Publications

Aquaculture production has prospered rapidly since the 1970s and is considered as a part of the rural development program in many countries. The impacts of aquaculture on the rural communities in terms of livelihood and food security are assessed in this paper. Aquaculture contributes to the livelihood of the poor through improved employment and income. Aquaculture creates job opportunities for rural communities, especially for illiterate women to earn side income for the household. With increased financial ability, household manage to reflect stronger purchasing power and have better access to the resources. However, there is a controversy among the researchers whether …

Technological Modernization And Its Impact On Agriculture, Fisheries And Fossil Fuel Utilization In The Asia Pacific Countries With Emphasis On Sustainability Perspective, Rajee Olaganathan, Kathleen Quigley

Publications

Modernization is a process that moves towards efficiency. This affects most of the fields such as agriculture, fisheries, forestry, urban planning, policy, fossil fuel usage, manufacturing, technology, economic growth etc. This process plays a major role in moving forward making things faster, better and basically more efficient. The effects of modernization on all these fields bring about the major changes to aspects such as social, economic and the environment. The level of operation has increased from a domestic level; small family scale business to large commercial levels. As the level of operation increased, the utilization of natural resources increased gradually …

Assessing The Efficiency Of Different Sustainable Farming Practices In Reducing The Environmental Impacts Caused By Aquaculture, Rajee Olaganathan, Alicia Tang Kar Mun

Publications

Sustainability of aquaculture is achieved when aquaculture farming systems are capable of preserving the natural resource base and involves an institutional change to the environment by the attainment and continued satisfaction for present and future generations. Sustainable farming practices produce sufficient aquaculture output to satisfy the seafood demand while not burdening the environment more. The potentiality and efficiency of different sustainable aqua farming practices in reducing anthropogenic impacts to the environment by aquaculture are assessed in this paper. Polyculture is mostly adopted by small-scale rural farmers as it requires low entry barrier and help in income diversification. The input of …