Life Sciences Commons^™

Effects Of Audible Human Disturbance On Koala (Phascolarctos Cinereus) Behavior In Queensland, Australia And Implications For Management, Galina Eugenia Kinsella

Honors Theses and Capstones

As the growing human population continues to encroach on wildlife habitat, species are forced to adapt in order to survive. In addition to causing habitat loss, human presence can create more subtle disturbances, such as noise pollution, that disrupt wildlife behavior. Adapting to human presence is particularly difficult for species with specialized resource needs or low mobility. The koala (Phascolarctos cinereus), a national icon of Australia, meets both these criteria. Koalas were once abundant throughout Australia, but are now classified as “threatened.” Habitat loss is at least partly responsible for this decline, but anthropogenic noise may also be …

Assessing The Fishery And Ecology Of Sharks In The United Arab Emirates, Rima W. Jabado

Dissertations

Large scale shark population declines have been documented worldwide due to overexploitation and the lack of adequate management frameworks to conserve shark stocks. This study aimed at gaining an understanding of the national shark fishery and the trade in shark products from the United Arab Emirates (UAE). Data were collected from June 2010 to October 2012 through interviews with local fishermen, market and landing site surveys, fishery independent surveys, and stomach content analysis. Interviews with local fishermen (n=126) provided information on the fishery characteristics and established that sharks were increasingly targeted due to their high value in the global fin …

The Effect Of Exercise Intensity On Physiological And Psychological Outcomes In Breast And Prostate Cancer Survivors: A Controlled Study, Eric Martin

Theses

Introduction

Research has identified a need to explore the components of exercise prescription for cancer survivors, particularly the most effective exercise intensity. The main purpose of this research was to examine whether exercise intensity modulates a range of physiological and psychological outcomes for breast and prostate cancer survivors. The primary outcomes were related to peak oxygen consumption (VO2peak) and quality of life (QOL). VO2peak is a highly sensitive measure that indicates overall health. QOL references the general wellbeing of individuals, and is an outcome of great importance in cancer rehabilitation research.

Pilot Study

A pilot study involving breast cancer survivors …

Characterisation Of The Enzybiotic Potential Of Selected Staphylococcus Aureus Bacteriophages, Ruth Keary

Theses

The work presented in this thesis focuses on harnessing the bactericidal potential of bacteriophage (phage) encoded peptidoglycan hydrolase enzymes to combat the significant pathogen Staphylococcus aureus. In order to identify novel peptidoglycan hydrolases lytic against S. aureus, the complete genomes of two staphylococcal temperate Siphoviridae bacteriophages, DW2 and CSl, were sequenced and annotated. Screening of these genomes identified genes for several putative peptidoglycan hydrolases including two endolysins and three virion-associated peptidoglycan hydrolases. The identification of putative genes relating to virulence and host fitness lends to the understanding of the role played by such temperate phages in the evolution of this …

Impact Of Nutrition On Cognition And Its Association With Blood And Brain Alzheimer Disease Related Biomarkers, Samantha Gardener

Theses: Doctorates and Masters

Alzheimer’s disease (AD), the most common form of senile dementia, currently affects over 35 million people worldwide. While there is no cure or effective treatment, early intervention programs hold considerable promise. Following particular dietary patterns represents one potential intervention strategy accessible to all.

Results from previous studies investigating the association of diet, cognition and biomarkers of AD are inconsistent: Positive results have been reported (1-7), whilst others have shown no associations. Prior to this thesis, no study has assessed the relationship of four dietary patterns to cognition, blood-based and neuroimaging biomarkers of AD in a large highly-characterised ageing cohort. Participants …

The Impact Of Sea Surface Temperature On Outbreaks Of Acanthaster Planci On The Great Barrier Reef, Laura A. Grossman

Scripps Senior Theses

The causes of increasing outbreaks of Acanthaster planci on the Great Barrier Reef have been a point of hot debate in recent years. It is unknown whether the increased success is due to nutrient runoff, salinity levels, or a decrease in predation, among other possibilities. In this paper I argue that the primary influence on outbreak status is sea surface temperature. From existing literature, I demonstrate that sea surface temperature in the Great Barrier Reef has increased by 0.4°C per year over the past three decades. I attempt to tie this increase with an increase in frequency of A. planci …

Antimicrobial Properties Of Vertically Aligned Nano-Tubular Copper, Kafil Razeeb, Joanna Podporska-Carroll, Mamun Jamal, Maksudul Hassan, Michael Nolan, Declan Mccormack, Brid Quilty, Simon Newcombe, Suresh Pillai

Articles

In this work, the antimicrobial properties of vertically aligned nano-tubular Cu arrays (NT-Cu) fabricated via a template-based electrodeposition approach were investigated. The NT-Cu display good bactericidal activity against S.aureus and bacteriostatic properties against E.coli, S.sonnei, S.enterica and C.albicans. In contrast, Cu-foil electrodeposited from the same solution shows low biological activity against the same microorganisms. The antimicrobial activity of NT-Cu depends on both the type of microorganism and exposure time. After 6 hours of exposure, over 99.99% (log red = 4.43) of S.aureus population was inactivated, whereas, for E.coli, S.sonnei, S.enterica and C.albicans it was 97.8, 94.2, 89.9, and 90.3%, respectively.

The Association Of Cold Weather And All-Cause And Cause-Specific Mortality In The Island Of Ireland Between 1984 And 2007, Ariana Zeka, Stephen Browne, Helen Mcavoy, Patrick Goodman

Articles

Background: This study aimed to assess the relationship between cold temperature and daily mortality in the Republic of Ireland (ROI) and Northern Ireland (NI), and to explore any differences in the population responses between the two jurisdictions. Methods: A time-stratified case-crossover approach was used to examine this relationship in two adult national populations, between 1984 and 2007. Daily mortality risk was examined in association with exposure to daily maximum temperatures on the same day and up to 6 weeks preceding death, during the winter (December-February) and an extended cold period (October-March), using distributed lag models. Model stratification by age and …

Knockanore Irish Farmhouse Cheese, Eamonn Lonergan

Pamphlets

No abstract provided.

Food Island, The Irish Times, A Special Report, The Irish Times

Pamphlets

No abstract provided.

Introduction: Tickling The Palate. Gastronomy In Irish Literature And Culture, Eamon Maher, Máirtín Mac Con Iomaire

Books/Chapters

There has been a gradual but noticeable growth in scholarship concerning food globally, particularly in the last decade. One of the longest running and most inf luential forces behind this phenomenon is the Oxford Symposium on Food and Cookery (1981–present) which was originally founded and co-chaired by Alan Davidson, pre-eminent food historian, diplomat, and author of The Oxford Companion to Food, and Dr Theodore Zeldin, the celebrated social historian of France. This spawned a dedicated publishing house, Prospect Books, which published the conference proceedings and also the journal Petits Propos Culinaires (PPC), now approaching its 100th issue.

Isolation And Characterization Of Natural Alpha-Glucosidase Inhibitors From Antioxidant Rich Red Wine Grapes (Vitis Vinifera), Hoda Chaouki Kadouh

Wayne State University Dissertations

Background: Diabetes is currently a global public health problem affecting people at all ages. Dietary antioxidants have been associated with a reduced risk of type 2 diabetes. Grape pomace contains considerable amounts of polyphenols and it has been reported to exhibit an inhibitory activity against alpha- glucosidases. Alpha-glucosidases, in turn, play a major role in controlling starch digestion and therefore postprandial blood glucose, a target for diabetes management.

Objective: This study aims to investigate the anti-diabetes potential of a selection of six grape pomaces and prepare and purify active components in the active variety that specifically inhibit intestinal alpha-glucosidases. The …

Combating Resistance To Epidermal Growth Factor Recpetor Inhibitors In Triple Negative Breast Cancer, Julie Marie Madden

Wayne State University Dissertations

Triple negative breast cancer (TNBC) patients suffer from a highly malignant and aggressive cancer that lacks an effective targeted therapeutic. Although many TNBCs, both in vitro and in vivo, have increased expression of epidermal growth factor receptor (EGFR), EGFR targeted inhibitors, such as gefitinib (GEF), have yet to demonstrate efficacy. Using mass spectrometry to identify pathways that remain activated in the presence of GEF, we found that components of the mTOR signaling pathway remain phosphorylated. While inhibiting mTOR with temsirolimus (TEM) decreased mTOR signaling, EGFR signaling pathways remained activated and the TNBC cell lines continued to proliferate. However, dual treatment …

A Genealogy Of Ecological Rhetoric: Heraclitus, Bacon, Darwin And Huxley, Jared Grogan

Wayne State University Dissertations

This dissertation is a genealogical study of historical intersections between rhetoric and ecology. Studying the works of Heraclitus, Francis Bacon, T.H. Huxley and Darwin as "bridge figures" in the history of rhetoric, science and ecological thought, I examine how their rhetorical theories and strategies (as discursive practices, performances and techniques) form a genealogy that bridges rhetorical and ecological theories and practices. My analysis studies their critical assessments and uses of rhetoric as it intersects with each figure's new investigations into natural philosophy, nature, and evolutionary biology, while drawing out relevant lessons for contemporary ecological and rhetorical thinkers. The main threads …

Vibrational Spectroscopy: Disease Diagnostics And Beyond, Hugh Byrne, Kamila Ostrowska, Haq Nawaz, Jennifer Dorney, Aidan Meade, Franck Bonnier, Fiona Lyng

Books/Book Chapters

Summary

This chapter outlines some developments in the applications of vibrational spectroscopy for disease diagnostics and demonstrates how the applications of the spectroscopic techniques can be extended to the analysis and evaluation of disease aetiology and the mechanisms of interaction and the cellular and subcellular responses to, for example chemotherapeutic agents and nanoparticles. The primary emphasis is on Raman spectroscopy, although some examples are based on infrared absorption spectroscopy. The studies presented are chosen to illustrate how a range of multivariate analytical techniques can be employed to maximize the potential benefits of the complex spectral information obtained from tissue or …

Modelling Cholera In Periodic Environments, Drew Posny, Jin Wang

Mathematics & Statistics Faculty Publications

We propose a deterministic compartmental model for cholera dynamics in periodic environments. The model incorporates seasonal variation into a general formulation for the incidence (or, force of infection) and the pathogen concentration. The basic reproduction number of the periodic model is derived, based on which a careful analysis is conducted on the epidemic and endemic dynamics of cholera. Several specific examples are presented to demonstrate this general model, and numerical simulation results are used to validate the analytical prediction.

The Ecology, Assembly, And Evolution Of Gypsophile Floras, Michael J. Moore, Juan F. Mota, Norman A. Douglas, Hilda Flores-Olvera, Helga Ochoterena

Faculty & Staff Scholarship

Gypsum (CaSO4·2H2O) exposures and gypseous soils occupy over 100 million ha worldwide, primarily in arid and semiarid regions, with particularly large areas of surface gypsum in southwestern Asia, the Mediterranean region, the Horn of Africa and southwestern North America. Each of these areas hosts a diverse assemblage of gypsum endemic plant taxa, known as gypsophiles. Although plant biologists have been interested in the causes of gypsophily for well over a century, it has only been over the past few decades that gypsophile floras have received sustained ecological and evolutionary study. Recent work, principally in Spain, has revealed that both physical …

Early Infant Feeding And Adiposity Risk: From Infancy To Adulthood, W H. Oddy, T A. Mori, R C Huang, J A. Marsh, C E. Pennell, Paola Chivers, Beth Hands, P Jacoby, P Rzehak, B V. Koletzko, L J. Beilin

Health Sciences Papers and Journal Articles

Introduction: Systematic reviews suggest that a longer duration of breast-feeding is associated with a reduction in the risk of later overweight and obesity. Most studies examining breast-feeding in relation to adiposity have not used longitudinal analysis. In our study, we aimed to examine early infant feeding and adiposity risk in a longitudinal cohort from birth to young adulthood using new as well as published data.

Methods: Data from the Western Australian Pregnancy Cohort (Raine) Study in Perth, W.A., Australia, were used to examine associations between breast-feeding and measures of adiposity at 1, 2, 3, 6, 8, 10, 14, 17, and …

Transcriptional Regulation Of Neurogenic Atrophy-Induced Gene Expression By Muscle Ring Finger-1 And Myogenic Regulatory Factors, Theodore Olson

UNF Graduate Theses and Dissertations

Skeletal muscle wasting is a consequence of numerous physiological conditions, including denervation, corticosteroid treatment, immobilization, and aging. The E3 ubiquitin ligases, MuRF1 and MAFbx, are induced under nearly all atrophy conditions and are believed to play a key role in protein degradation in atrophying muscle. However, the preliminary data described in this study provides new evidence that MuRF1 may also act as a transcriptional modulator of atrophy-induced gene activity, including the regulation of MAFbx and MuRF1 expression. To characterize the transcriptional regulation of MuRF1 and MAFbx, reporter gene constructs containing fragments of the proximal promoter regions of these genes were …

Investigating The Role Of Dachshund Homolog 1 (Dach1) And Mir-200b In Group 4 Medulloblastoma Pathogenesis, Courtney George

Theses : Honours

Medulloblastoma is the most common malignant childhood brain tumour, and the most significant cause of childhood cancer-related mortality. Recently four core molecular medulloblastoma sub-groups have been identified, with distinct pathogenesis and responses to therapies. Current therapies, do not account for this molecular variation, and many patients may receive inappropriate treatment. To address this, targeted therapies for each molecular sub-group would be ideal. Unfortunately, for the more aggressive Group 3 and Group 4 subgroups, the underlying mechanisms of pathogenesis remain poorly understood. The current challenge is to identify the key tumour suppressors or oncogenes involved in Group 3 and Group 4 …

The Conservation Value Of Karst Dolines For Vascular Plants In Woodland Habitats Of Hungary: Refugia And Climate Change, Zoltán Bátori, János Csiky, Tünde Farkas, E. Anna Vojtkó, László Erdős, Dániel Kovács, Tamás Wirth, László Körmöczi, András Vojtkó

International Journal of Speleology

Limestone (karst) surfaces in Hungary are rich in dolines, in which many endangered vascular plant species occur. To date, the majority of studies dealing with doline vegetation have focused on the local rather than the landscape level, without using comparative data from other areas. However, in this study we aimed to compare the vegetation pattern and species composition of dolines under different climate regimes of Hungary with regard to regional species pools. The fieldwork was carried out between 2005 and 2012. Twenty dolines were selected in the Mecsek Mountains (southern Hungary) and nine dolines in the Aggtelek Karst area (northern …

Ground Arthropod Abundance In Switchgrass And Diverse Prairie Agroenergy Crops, Stephanie Paape, Libby Torresani, Mark C. Myers

Undergraduate Student Work

The University of Northern Iowa’s Tallgrass Prairie Center converted corn and soybean fields in the Cedar River Natural Resource Area to four mixes of perennial tallgrass prairie species. Research plots were randomly seeded with one of four treatments of native prairie vegetation including a switchgrass monoculture and a 32-species prairie mix. We studied ground arthropod abundance in Switchgrass and the 32-species prairie mix at various distances from the nearest woody edge using pitfall traps. We hypothesized that a 32-species Prairie mix would support greater numbers of ground arthropods than a Switchgrass monoculture and that ground arthropod abundance would be greater …

Grassland Bird Nest Survival In Perennial Agroenergy Crops, Libby Torresani, Stephanie Paape, Mark C. Myers

Undergraduate Student Work

Previous research had been done in 2011 and 2012 regarding bird nest survival rates in the Cedar River Natural Resource Area in Washburn, IA. Further analysis of bird nest survival rates was done in this study to research how nest age, calendar date, soil type, and vegetation type influence the success or failure of these nests. New nests were identified in the prairie plots of the Cedar River Natural Resource Area and added to the previous sample size from the original study. A sample size of 97 bird nests total and 67 Dickcissel nests –SPAM (Spiza Americana) were …

Tracing Beta Strands Using Strandtwister From Cryo-Em Density Maps At Medium Resolutions, Dong Si, Jing He

Computer Science Faculty Publications

Major secondary structure elements such as α helices and β sheets can be computationally detected from cryoelectron microscopy (cryo-EM) density maps with medium resolutions of 5–10 A˚ . However, a critical piece of information for modeling atomic structures is missing, because there are no tools to detect β strands from cryo-EM maps at medium resolutions. We propose a method, StrandTwister, to detect the traces of β strands through the analysis of twist, an intrinsic nature of a β sheet. StrandTwister has been tested using 100 β sheets simulated at 10 A˚ resolution and 39 β sheets computationally detected from cryo-EM …

She’S A Femme Fatale: Low-Density Larval Development Produces Good Disease Vectors, Steven A. Juliano, Gabriel Sylvestre Ribeiro, Rafael Maciel-De-Freitas, Márcia G. Castro, Claudia Codeço, Ricardo Lourenço-De-Oliveira, L Philip Lounibos

Faculty Publications – Biological Sciences

Two hypotheses for how conditions for larval mosquitoes affect vectorial capacity make opposite predictions about the relationship of adult size and frequency of infection with vector-borne pathogens. Competition among larvae produces small adult females. The competition-susceptibility hypothesis postulates that small females are more susceptible to infection and predicts frequency of infection should decrease with size. The competition-longevity hypothesis postulates that small females have lower longevity and lower probability of becoming competent to transmit the pathogen and thus predicts frequency of infection should increase with size. We tested these hypotheses for Aedes aegypti in Rio de Janeiro, Brazil, during a dengue …

An In Vivo Assay For Simultaneous Monitoring Of Neuronal Activity And Behavioral Output In The Stomatogastric Nervous System Of Decapod Crustaceans, Wolfgang Stein, Florian Diehl

Faculty Publications – Biological Sciences

Central pattern generators (CPGs) generate rhythmic output patterns and drive vital behaviors such as breathing, swallowing, locomotion and chewing ^1-10. While most insights into the rhythm generating mechanisms of CPGs have been derived from isolated nervous system preparations, the relationship between neural activity and corresponding behavioral expression is often unclear. The stomatogastric system of decapod crustaceans is one of the best characterized neural system for motor pattern generation ^9-12 and many mechanisms of motor pattern generation and selection have been discovered in this system. Since most studies are limited to the isolated nervous system, little is known about the …

Spatial And Temporal Habitat Segregation Of Mosquitoes In Urban Florida, Paul T. Leisnham, Shannon L. Ladeau, Steven A. Juliano

Faculty Publications – Biological Sciences

Understanding mechanisms fostering coexistence between invasive and resident species is important in predicting ecological, economic, or health impacts of invasive species. The non-native mosquitoes Aedes aegypti and Culex quinquefasciatus have been resident in the southeastern United States for over a century. They coexist at some urban sites with the more recent invasive Aedes albopictus, which is usually superior in interspecific competition. We tested predictions of temporal and spatial habitat segregation that foster coexistence of these resident species with the superior invasive competitor. We measured spatial and temporal patterns of site occupancy and abundance for all three species among standard oviposition …

The Effects Of Beaver Dams On The Structure And Function Of Invertebrate Communities In A Southeastern Coastal Plain Stream, Damon L. Mullis

College of Graduate Studies: Theses & Dissertations

Beaver were at the brink of extinction in the early 20^th century, but over the past century populations have been rebounding. This increase in range and population size has raised new concerns over possible impacts on aquatic ecosystems. Beaver are considered ecosystem engineers because they change the physical structure of aquatic systems through the construction of dams, which turn naturally flowing sections of rivers and streams into standing water. Such changes are known to influence habitat heterogeneity, influence organic matter transport and storage, and consequentially influence biological diversity. To my knowledge, no studies of the effects of beaver impoundments …

Effects Of Organic And Conventional Agricultural Practices On Soil Microbial Communities And Molecular Detection Of Soil Borne Disease, Holli K. Milner

College of Graduate Studies: Theses & Dissertations

Agricultural practices affect soil microbial communities and health through the input of pesticides, herbicides, fertilizers, and cycling of crop rotation. By examining the microbial community structure, we analyzed how microbial species respond to the environment that individual farms create. Early detection of soil borne disease is essential for agricultural success. However, monitoring incidence of disease based on plant growth response to pathogenic inoculation may not reveal the amount of pathogenic DNA in soil. A comparative study of tomato production systems was conducted by analysis of soil microbial community structure from four farms in Southeast Georgia for the years 2012 and …

Integrated Decision Support For Sustainable And Profitable Land Management In The Lowlands Of Central Asia, Nodir Djanibekov, Rolf Sommer

All Peer-Reviewed Publications

Land use and crop production in the Khorezm region in western Uzbekistan, exemplarily for the irrigated lowlands of Central Asia, are challenged by the excessive, non-sustainable use of irrigation water and repeated water shortages on one hand, and soil degradation by secondary salinization on the other hand. One of the research objectives of the German-Uzbek Khorezm project, funded by the German Ministry for Education and Research (BMBF) and led by Center of Development Research (ZEF) of Bonn University, was to better understand options for land use and choice of technology at the farm level in order to evaluate and propose …