Life Sciences Commons^™

Analysis Of Sources Of Variation And Relationships Among Sow Productivity Traits, Richard L. Cutshaw

Open Access Theses

The swine industry has witnessed major changes in the past three decades in terms of selection tools and implementation of effective selection. As the pork industry continues to consolidate, it is increasingly important to be able to accurately predict and direct future performance toward increased overall profitability. Overall, sow productivity greatly affects a pork producer's ability to be profitable in the industry and have sufficient knowledge of production levels to improve the likelihood of remaining profitable into the future.

The relationships among sow productivity traits including total number born, litter birth weight, number weaned, preweaning survival, mean piglet birth weight, …

Sustainable Production Of Swine: Putting Lipstick On A Pig?, Michelle B. Nowlin

Faculty Scholarship

No abstract provided.

Activation Of Gper Induces Differentiation And Inhibition Of Coronary Artery Smooth Muscle Cell Proliferation, F. Li, X. Yu, C. K. Szynarski, C. Meng, B. Zhou, R. Barhoumi, Richard E. White, C. L. Heaps, J. N. Stallone, G. Han

PCOM Scholarly Papers

Background:Vascular pathology and dysfunction are direct life-threatening outcomes resulting from atherosclerosis or vascular injury, which are primarily attributed to contractile smooth muscle cells (SMCs) dedifferentiation and proliferation by re-entering cell cycle. Increasing evidence suggests potent protective effects of G-protein coupled estrogen receptor 1 (GPER) activation against cardiovascular diseases. However, the mechanism underlying GPER function remains poorly understood, especially if it plays a potential role in modulating coronary artery smooth muscle cells (CASMCs).Methodology/Principal Findings:The objective of our study was to understand the functional role of GPER in CASMC proliferation and differentiation in coronary arteries using from humans and swine models. We …

Electroporation-Mediated Gene Transfer Directly To The Swine Heart, Barbara Hargrave, Harre Downey, Cathryn Lundberg, Annelise Israel, Yeong-Jer Chen, Richard Heller

Bioelectrics Publications

In vivo gene transfer to the ischemic heart via electroporation holds promise as a potential therapeutic approach for the treatment of heart disease. In the current study, we investigated the use of in vivo electroporation for gene transfer using three different penetrating electrodes and one non-penetrating electrode. The hearts of adult male swine were exposed through a sternotomy. Eight electric pulses synchronized to the rising phase of the R wave of the electrocardiogram were administered at varying pulse widths and field strengths following an injection of either a plasmid encoding luciferase or one encoding green fluorescent protein. Four sites on …