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Articles 151 - 180 of 2477
Full-Text Articles in Life Sciences
Editorial Board & Iowa Academy Of Science Officers And Directors
Editorial Board & Iowa Academy Of Science Officers And Directors
Journal of the Iowa Academy of Science: JIAS
No abstract provided.
Interferon Regulatory Factor 7: A Key Cellular Mediator Of Lmp-1 In Ebv Latency And Transformation, Luwen Zhang, Joseph S. Pagano
Interferon Regulatory Factor 7: A Key Cellular Mediator Of Lmp-1 In Ebv Latency And Transformation, Luwen Zhang, Joseph S. Pagano
Nebraska Center for Virology: Faculty Publications
Interferon regulatory factor 7 (IRF-7) was cloned within the biological context of Epstein–Barr virus (EBV) latency, and has an intimate relation with EBV. EBV latent membrane protein 1 (LMP-1) regulates IRF-7 both by inducing the expression of IRF-7 and by activating IRF-7 protein through phosphorylation and nuclear translocation in a post-translational manner. The activated IRF-7 then functions to regulate both EBV and cellular target genes involved in latency, transformation and immune regulation. IRF-7 appears to be a key cellular latency protein involved in both the pathogenesis and persistence of EBV infection.
Identification Of A Cellular Protein That Interacts And Synergizes With The Rta (Orf50) Protein Of Kaposi’S Sarcoma-Associated Herpesvirus In Transcriptional Activation, Shizhen Wang, Shuhong Liu, Ming-Hoi Wu, Yunqi Geng, Charles Wood
Identification Of A Cellular Protein That Interacts And Synergizes With The Rta (Orf50) Protein Of Kaposi’S Sarcoma-Associated Herpesvirus In Transcriptional Activation, Shizhen Wang, Shuhong Liu, Ming-Hoi Wu, Yunqi Geng, Charles Wood
Nebraska Center for Virology: Faculty Publications
Lytic reactivation of Kaposi’s sarcoma-associated herpesvirus (KSHV), or human herpesvirus 8, from latency requires transcriptional transactivation by the viral protein RTA encoded by the ORF50 gene. Very little is known about how RTA functions and the cellular factors that may be involved in its transactivation function. Using the yeast two-hybrid system, we have identified a human cellular protein that can interact with KSHV RTA. The cellular protein, referred to as the human hypothetical protein MGC2663 by GenBank, is encoded by human chromosome 19. This protein is 554 amino acids (aa) in size and displays sequence similarity with members of the …
Index From Nebraska Bird Review December 2001 Volume 69 Number 4
Index From Nebraska Bird Review December 2001 Volume 69 Number 4
Nebraska Bird Review
INDEX (12 pages) A-Z
Adams, Betty 23
Alexander, Irene 23
Allen, Elizabeth 3, 47,159
Allison, Mary 22
American, Redstart 184
Amiotte, Sue 48
Andrews, Ron 5
Anhinga 161
Arizona 96
Avocet, American 37, 57, 94, 116, 140, 169, 204
Babbitt, Charles E. 133
Bachel, Elaine 47
Badura, Laurel 47, 160
Barth, Roland 48
Bedows, Elliott 23, 107, 159
Beede, Dillon 22
Benson, Joan 18
Bielenburg, Warren 23
Yellowlegs
Greater 37, 46, 57, 116, 142, 146,148,169
Lesser 38,46, 57, 116, 133, 136-137,140,142,147,169
sp. 204
Yellowthroat, Common 40, 73, 128, 151,158,185
Young, Kay 23
Masthead From Nebraska Bird Review December 2001 Volume 69 Number 4
Masthead From Nebraska Bird Review December 2001 Volume 69 Number 4
Nebraska Bird Review
The Nebraska Bird Review (http://rip.physics.unk.eduINOU/) is published quarterly by the Nebraska Ornithologists' Union, Inc., as its official journal, and is sent to members not in arrears of dues. Annual subscription rates (on a calendar-year basis only): $14.00 in the United States; $18.00 for all foreign countries, payable in advance. Single copies are $4.00 each, postpaid, in the United States, and $5.00 elsewhere. Send orders for back issues to Mary Prichard, NOU Librarian, University of Nebraska State Museum, Lincoln, NE 68588-0514.
Memberships in NOU (on a calendar year basis only): Active, $15.00; Sustaining, $25.00; Student, $10.00; Family Active, $20.00; Family Sustaining, …
Xalpirta, N. Gen., And Crotch (1876) From Chile And South America (Coleoptera: Erotylidae: Tritominae), Paul E. Skelley, Tomas Cekalovic K.
Xalpirta, N. Gen., And Crotch (1876) From Chile And South America (Coleoptera: Erotylidae: Tritominae), Paul E. Skelley, Tomas Cekalovic K.
Insecta Mundi
Members of the genera Neoxestus Crotch (1876) and Xalpirta, n. gen., are revieewed. Neoxestus is an endemic Chlean genus of flightless species. Xalpirta has 9 species restricted to southern South American, most of which are found only in Chile. New species described are Neoxestus cauquenes, N. lucile, N. nahuelbuta, N. nonguen, N. norma, Xalpirtaelsa, X. stellaris, X. arnetti, and X. peckorum. A new name, Xalpirtaguerini, nom. nov., is proposed for the species Triplaxbicolor Guerin (1952). Diagnoses, keys to species, maps and illustrations are provided for the genera and species.
First Records Of The Subfamily Acaenitinae In Florida (Hymenoptera: Ichneumonidae), Charles C. Porter
First Records Of The Subfamily Acaenitinae In Florida (Hymenoptera: Ichneumonidae), Charles C. Porter
Insecta Mundi
Acaenitines have five genera and 18 species in North American forests (Townes 1960). Several of these occur in the eastern United States, but none is recorded from Florida; however, recent fieldwork in Florida yielded four species: Arotes decorus (Say), Spilopteron formosum (Cresson), S. occiputale (Cresson) and S. vicinum (Cresson) . These inhabit mature forests and attack wood-boring beetle larvae in dead trunks. There are no Florida host records, but Townes (1960) and Cushman and Rohwer (1920) report that in the northeastern states A. decorus was reared from Tomoxia (Mordellidae) in Carya (Juglandaceae), S. formosum from Bellamira (Cerambycidae) in Betula (Betulaceae), …
Scale Insects (Hemiptera: Coccoidea) Of Ornamental Plants From SãO Carlos, SãO Paulo, Brazil, A. L. B. G. Peronti, D. R. Miller, C. R. Sousa-Silva
Scale Insects (Hemiptera: Coccoidea) Of Ornamental Plants From SãO Carlos, SãO Paulo, Brazil, A. L. B. G. Peronti, D. R. Miller, C. R. Sousa-Silva
Insecta Mundi
A list of 35 scale insects collected from 72 ornamental plant species in São Carlos, São Paulo, Brazil is provided. Regarding host specificity, 30 scale insects were polyphagous, 4 oligophagous, and 1 monophagous. A total of 102 coccoid/plant associations are recorded, 29 of which are new host records for the species; 60 are new host records for the species in Brazil. Pulvinaria urbicola Cockerell, 1893 (Coccidae), Phenacoccus similis Granara de Willink, 1983 (Pseudococcidae), and Orthezia molinarii (Morrison, 1952) (Ortheziidae) are recorded for the first time in Brazil. In addition, we describe the injury caused by scale insects on ornamental plants.
Resistance Of Commercial Hybrids And Lines Of Sorghum, Sorghum Bicolor (L.) Moench., To Diatraea Saccharalis (Fabr.) (Lepidoptera: Pyralidae), Jose M. Waquil, Jose A. S. Rodrigues, Fredolino G. Santos, Alexandre S. Ferreira, Francys M. F. Vilella, John E. Foster
Resistance Of Commercial Hybrids And Lines Of Sorghum, Sorghum Bicolor (L.) Moench., To Diatraea Saccharalis (Fabr.) (Lepidoptera: Pyralidae), Jose M. Waquil, Jose A. S. Rodrigues, Fredolino G. Santos, Alexandre S. Ferreira, Francys M. F. Vilella, John E. Foster
Department of Entomology: Faculty Publications
Commercial sorghum hybrids and Embrapa’s lines were evaluated regarding resistance to sugarcane borer. Two field experiments were conducted in Sete Lagoas, MG, under natural infestation, during the second cropping season in a randomized complete block with 3 replicates. The plants were evaluated regarding to stand, maturity cycle, plant height, and number of broken or lodging stalks and yield. The borer incidence, number of galleries, number of healthy and damaged nodes were also evaluated to calculate the Infestation Index and Intensity Infestation Index. Among the commercial sorghum hybrids, Br 304 and CMSXS 9701 were the least infested wile Z 732 and …
Groundwater Study Of The Mullewa Townsite, Russell John Speed
Groundwater Study Of The Mullewa Townsite, Russell John Speed
Resource management technical reports
A groundwater study was carried out in the townsite of Mullewa, Western Australia. It aimed to accelerate the implementation of effective salinity management options. The study consisted of a drilling investigation, installation of a piezometer network, groundwater flow modelling and a flood risk analysis.
Groundwater Study Of The Woodanilling Townsite, Ben Whitfield
Groundwater Study Of The Woodanilling Townsite, Ben Whitfield
Resource management technical reports
A groundwater study was carried out in the townsite of Woodanilling, Western Australia. It aimed to accelerate the implementation of effective salinity management options. The study consisted of a drilling investigation, installation of a piezometer network, groundwater flow modelling and a flood risk analysis.
Arboles Trabajando En Benficio De La Agricultura
Arboles Trabajando En Benficio De La Agricultura
Working Trees (USDA-NAC)
Imagine por un momento que en su finca usted cuenta con un producto capaz de controlar la erosión, aumentar el rendimiento de las cosechas y absorber los contaminantes en aguas de escorrentía. ¿Y que le parece si además pudiera proteger a los animales de fuertes vientos y temperaturas críticas, a la vez que éstos animales aumentan de peso y reducen los gastos de energía? Un producto que provea fuentes adicionales de ingreso y que provea diversidad al medioambiente, mantenga las aguas limpias y atraiga más vida silvestre. Seguramente la mayoría de nosostros correríamos a comprarlo.
Por supuesto un producto como …
Oestrus Ovis In Sheep: Relative Third-Instar Populations, Risks Of Infection And Parasitic Control, Guillaume Tabouret, Philippe Jacquiet, Philip Scholl, Philippe Dorchies
Oestrus Ovis In Sheep: Relative Third-Instar Populations, Risks Of Infection And Parasitic Control, Guillaume Tabouret, Philippe Jacquiet, Philip Scholl, Philippe Dorchies
United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications
Oestrus ovis (L.) (Diptera: Oestridae), the nasal bot fly, has a relatively short free-living life cycle outside of the host, and therefore it is necessary to know when the parasitic period occurs in order to prevent the clinical signs and economic losses caused by this parasite. The length of this parasitic portion of the life cycle is quite variable: a few weeks to several months depending on the season and climatic conditions. Surveys of Oestrus ovis larval populations in sheep show different results on the number of generations according to the local climate. Mean monthly larval profiles of L1 and …
Ultrasound Based Quantitative Motion Measurement Using Speckle Size Estimation, James D. Hamilton, Larry Y. L. Mo, Gregory R. Bashford
Ultrasound Based Quantitative Motion Measurement Using Speckle Size Estimation, James D. Hamilton, Larry Y. L. Mo, Gregory R. Bashford
Biomedical Imaging and Biosignal Analysis Laboratory
An ultrasound system determines the relative movement in a first direction (F1) of first matter, such as blood flow, and second matter, such as an artery wall, in a subject under study (S). A beam (B1) of ultrasound waves defining a plurality of beam positions (BP1 and BP2) and beam axes (A1 and A2) are moved in scan direction having components parallel to direction F1. First and second blocks of data representing the first and second matter, respectively, are generated. A processor (20) performs an estimation of speckle size on first data to obtain a first result, and performs analysis …
Identification Of Screwworms, Cochliomyia Hominivorax (Coquerel) (Diptera: Calliphoridae), With A Monoclonal Antibody-Based Enzyme-Linked Immunosorbent Assay (Mab-Elisa), J. L. Figarola, Steven R. Skoda, Dennis R. Berkebile, John E. Foster
Identification Of Screwworms, Cochliomyia Hominivorax (Coquerel) (Diptera: Calliphoridae), With A Monoclonal Antibody-Based Enzyme-Linked Immunosorbent Assay (Mab-Elisa), J. L. Figarola, Steven R. Skoda, Dennis R. Berkebile, John E. Foster
Department of Entomology: Faculty Publications
Myiasis caused by screwworms, Cochliomyia hominivorax (Coquerel), is devastating to warmblooded animals and economically important to livestock producers. It is difficult to distinguish these pests, immature screwworms, from immatures of other non-pest fly species that often occur in animal wounds; it would be helpful to have tools available that do not rely on morphological characteristics. We developed twomonoclonal antibodies (MAbs), highly specific for the screwworm, and used them in an enzyme-linked immunosorbent assay (MAb-ELISA), that differentiated screwworm eggs, larvae, pupae, and adults from those of the closely related secondary screwworm, C. macellaria (Fabricius) as well as Phormia regina (Meigen), Phaenicia …
Nebraska Cooperative Council 56th Annual Meeting, John Owens
Nebraska Cooperative Council 56th Annual Meeting, John Owens
John Owens: Speeches and Appearances
What a pleasure it is to be with you this morning - thank you for inviting me. I am looking forward to visiting with as many of you as possible while I am here today, and hope to have the opportunity to visit with you more as we meet again at other times and other places. One of the things I am always interested in knowing is what you perceive as Nebraska's greatest needs, now and in the future, and which of those Needs you think the University of Nebraska Institute of Agriculture and Natural Resources can most efficiently and …
Gamma Sigma Delta Award Of Merit Recipient Introductions, John Owens
Gamma Sigma Delta Award Of Merit Recipient Introductions, John Owens
John Owens: Speeches and Appearances
One of my most delightful parts of my job is being able to be part of recognizing outstanding individuals for their tremendous achievements. It is my pleasure to join you in recognizing two such individuals tonight as we present each of them with a Gamma Sigma Delta Award of Merit.
Laboratory Evaluation Of The Entomopathogenic Fungus, Metarhizium Anisopliae For The Control Of The Groundnut Bruchid, Caryedon Serratus On Groundnut, S. Ekesi, E. A. Egwurube, A. D. Akpa, I. Onu
Laboratory Evaluation Of The Entomopathogenic Fungus, Metarhizium Anisopliae For The Control Of The Groundnut Bruchid, Caryedon Serratus On Groundnut, S. Ekesi, E. A. Egwurube, A. D. Akpa, I. Onu
All Peer-Reviewed Publications
The pathogenicity of five isolates of Metarhizium anisopliae to adult Caryedon serratus was evaluated in the laboratory. All the isolates tested were virulent to the beetle but pathogenicity varied among the isolates. One isolate, CPD 4 was consistently superior to all other isolates in terms of mortality of the beetle, protection of groundnut pods from damage, reduction in progeny production and repellency to the beetle. At 10 days post-treatment, adult mortality treated with 0.1, 0.5 and 1.0 g of dry conidia equivalent to 3.6 × 108, 1.8 × 109 and 3.6 × 109 conidia of isolate CPD 4 per 50 …
The Ns5a Protein Of Bovine Viral Diarrhoea Virus Interacts With The Α Subunit Of Translation Elongation Factor-1, Craig M. Johnson, Daniel R. Perez, Roy C. French, William C. Merrick, Ruben O. Donis
The Ns5a Protein Of Bovine Viral Diarrhoea Virus Interacts With The Α Subunit Of Translation Elongation Factor-1, Craig M. Johnson, Daniel R. Perez, Roy C. French, William C. Merrick, Ruben O. Donis
Department of Plant Pathology: Faculty Publications
A cellular protein that interacts with the NS5A polypeptide of bovine viral diarrhoea virus (BVDV) was identified in a yeast two-hybrid screen. The NS5A interactor was identified as the a subunit of bovine translation elongation factor 1A (eEF1A). Cell-free binding studies were performed with chimeric NS5A fused to glutathione S-transferase (GST–NS5A) expressed in bacteria. GST–NS5A bound specifically to both in vitro-translated and mammalian cell-expressed eEF1A. Moreover, purified eEF1A bound specifically to GST–NS5A attached to a solid phase. Conservation of this interaction was then analysed using a set of NS5A proteins derived from divergent BVDV strains encompassing known biotypes and genotypes. …
The Effect Of Thermal Stress On The Mating Behavior Of Three Drosophila Species, Zachary J. Patton, Robert A. Krebs
The Effect Of Thermal Stress On The Mating Behavior Of Three Drosophila Species, Zachary J. Patton, Robert A. Krebs
Biological, Geological, and Environmental Faculty Publications
Selection may act on the weakest link in fitness to change how a species adapts to an environmental stress. For many species, this limitation may be reproduction. After adult Drosophila melanogaster, Drosophila simulans, and Drosophila mojavensis males were exposed to varying levels of thermal stress well below those that endanger life, courtship and mating frequency declined. The regression coefficients of both courtship and mating success did not differ significantly between D. melanogaster and D. simulans males. In contrast, significant differences were present between the two cosmopolitan species and D. mojavensis. Courtship frequency decreased at a much slower rate in D. …
Xenogeniates, A New And Unusual Genus Of Geniatine Scarab (Coleoptera: Scarabaeidae: Rutelinae: Geniatini) From Brazil, Karla Villatoro, Mary Liz Jameson
Xenogeniates, A New And Unusual Genus Of Geniatine Scarab (Coleoptera: Scarabaeidae: Rutelinae: Geniatini) From Brazil, Karla Villatoro, Mary Liz Jameson
University of Nebraska State Museum: Entomology Papers
A new genus and species of geniatine scarab is described from southeastern Brazil. The genus Xenogeniates is characterized by the unusual shape of the mesosternum, which is strongly invaginated and concave. Unusual characteristics of the taxon are discussed in relation to the Rutelinae and the Scarabaeidae.
Effect Of Cooling Rate On Crystallization Behavior Of Milk Fat Fraction/Sunflower Oil Blends, Silvana Martini, M. L. Herrera, R. W. Hartel
Effect Of Cooling Rate On Crystallization Behavior Of Milk Fat Fraction/Sunflower Oil Blends, Silvana Martini, M. L. Herrera, R. W. Hartel
Nutrition, Dietetics, and Food Sciences Faculty Publications
The effect of cooling rate (slow: 0.1°C/min; fast: 5.5°C/min) on the crystallization kinetics of blends of a highmelting milk fat fraction and sunflower oil (SFO) was investigated by pulsed NMR and DSC. For slow cooling rate, the majority of crystallization had already occurred by the time the set crystallization temperature had been reached. For fast cooling rate, crystallization started after the samples reached the selected crystallization temperature, and the solid fat content curves were hyperbolic. DSC scans showed that at slow cooling rates, molecular organization took place as the sample was being cooled to crystallization temperature and there was fractionation …
Fisheries Research Report No. 136 - Assessment Of Gonad Staging Systems And Other Methods Used In The Study Of The Reproductive Biology Of Narrow-Barred Spanish Mackerel, Scomberomorus Commerson, In Western Australia, Michael C. Mackie, Paul Lewis
Fisheries Research Report No. 136 - Assessment Of Gonad Staging Systems And Other Methods Used In The Study Of The Reproductive Biology Of Narrow-Barred Spanish Mackerel, Scomberomorus Commerson, In Western Australia, Michael C. Mackie, Paul Lewis
Fisheries Research Reports
Recent research by the Department of Fisheries in Western Australia into the reproductive biology of narrow-barred Spanish mackerel has required the use of various field and laboratory techniques. This report documents the procedures and adaptations of some of these techniques. Assessment and development of illustrated, relevant macroscopic and microscopic staging systems were of particular focus because both have been essential components of the research. The simplified and more reliable macroscopic staging system we developed allowed full use of all gonad samples and a more complete (albeit less distinct) overview of the seasonal pattern of gonad reproductive development. This macroscopic staging …
Re-Evaluating Nadph-Diaphorase Histochemistry As An Indicator Of Nitric Oxide Synthase: An Examination Of The Olfactory System Of Coho Salmon (Oncorhynchus Kisutch), Sean C. Lema, Gabrielle A. Nevitt
Re-Evaluating Nadph-Diaphorase Histochemistry As An Indicator Of Nitric Oxide Synthase: An Examination Of The Olfactory System Of Coho Salmon (Oncorhynchus Kisutch), Sean C. Lema, Gabrielle A. Nevitt
Biological Sciences
The NADPH-diaphorase (NADPH-d) histochemical technique is commonly used to localize the nitric oxide (NO)-producing enzyme NO synthase (NOS) in neural tissues. In the olfactory tissues of vertebrates, however, NADPH-d staining can be present without the detection of NOS by other methods. We used pharmacological controls to determine whether NADPH-d staining was indicative of NOS in olfactory tissues from coho salmon (Oncorhynchus kisutch). We also compared NADPH-d staining with immunoreactivity to NOS. NADPH-d staining localized to the olfactory epithelium and to the glomerular layer of the olfactory bulb. Two NOS inhibitors, L-N-nitroarginine and L-N-methyl-L-arginine, failed …
Area-Level Characteristics And Smoking In Women, Marilyn Tseng, Karin Yeatts, Robert Millikan, Beth Newman
Area-Level Characteristics And Smoking In Women, Marilyn Tseng, Karin Yeatts, Robert Millikan, Beth Newman
Kinesiology and Public Health
Objectives. This study examined whether area-level characteristics are associated with individual smoking behavior among women.
Methods. Analyses included 648 women enrolled as control patients in the Carolina Breast Cancer Study (1993–1996). Smoking and covariate information was obtained from interviews. Area-level characteristics included census block-group education level, poverty, unemployment, car–home ownership, crowding, and, for 431 women, city-level crime rates.
Results. In multivariate logistic regression models, no area characteristics were clearly associated with a history of smoking. Among those who had ever smoked, continued smoking was associated with living in low-education areas (odds ratio [OR] = 1.7, 95% confidence interval [CI] = …
Groundwater Study Of The Tambellup Townsite, Ben Whitfield
Groundwater Study Of The Tambellup Townsite, Ben Whitfield
Resource management technical reports
A groundwater study of the townsite of Tambellup. It aimed to accelerate the implementation of effective salinity management options. The study consisted of drilling investation and installation of a piezometer network, a pumping test, groundwater flow modelling and a flood risk analysis.
Interactions Between Shoal Size And Conformity In Guppy Social Foraging, Rachel L. Day, Tom Macdonald, Culum Brown, Kevin N. Laland, Simon M. Reader
Interactions Between Shoal Size And Conformity In Guppy Social Foraging, Rachel L. Day, Tom Macdonald, Culum Brown, Kevin N. Laland, Simon M. Reader
Sentience Collection
Previous experimental studies have established that shoaling fish forage more effectively in large than small groups. We investigated how shoal size affects the foraging efficiency of laboratory populations of the guppy, Poecilia reticulata, exposed to different foraging tasks. Experiment 1 confirmed the prediction that in open water the first fish and focal fish of larger shoals locate food faster than in smaller shoals. However, a second experiment, in which shoals of fish were required to swim through a hole in an opaque partition to locate food, found the reverse pattern: smaller shoals learned to complete the task faster than large …
Kentucky Warbler (Vol. 77, No. 4), Kentucky Library Research Collections
Kentucky Warbler (Vol. 77, No. 4), Kentucky Library Research Collections
The Kentucky Warbler
No abstract provided.
Fisheries Research Report No. 130 - Environmental Requirements And Tolerances Of Rainbow Trout (Oncorhynchus Mykiss) And Brown Trout (Salmo Trutta) With Special Reference To Western Australia: A Review, Brett W. Molony
Fisheries Research Reports
Both Oncorhynchus mykiss (rainbow trout) and Salmo trutta (brown trout) have a long history of translocation and culture and a wide knowledge base exists. O.mykiss is being considered as a candidate for inland aquaculture in the salinity affected areas of southern Western Australia and this review aims, in part, at providing relevant information to those considering a trout-framing venture in Western Australia. Both species of trout can survive a wide range of environmental conditions, including temperature, salinity, pH, dissolved oxygen and ammonia, with O.mykiss having a higher temperature tolerance than S.trutta. However, within the ranges of environmental conditions, each species …
Knowledge Discovery In Biological Datasets Using A Hybrid Bayes Classifier/Evolutionary Algorithm, Michael L. Raymer, Leslie A. Kuhn, William F. Punch
Knowledge Discovery In Biological Datasets Using A Hybrid Bayes Classifier/Evolutionary Algorithm, Michael L. Raymer, Leslie A. Kuhn, William F. Punch
Kno.e.sis Publications
A key element of bioinformatics research is the extraction of meaningful information from large experimental data sets. Various approaches, including statistical and graph theoretical methods, data mining, and computational pattern recognition, have been applied to this task with varying degrees of success. We have previously shown that a genetic algorithm coupled with a k-nearest-neighbors classifier performs well in extracting information about protein-water binding from X-ray crystallographic protein structure data. Using a novel classifier based on the Bayes discriminant function, we present a hybrid algorithm that employs feature selection and extraction to isolate salient features from large biological data sets. The …