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Articles 631 - 660 of 5010
Full-Text Articles in Life Sciences
Monitoring The Effectiveness Of Wildlife Exits And Bobcat Use Along A South Texas Highway, Jamie E. Langbein
Monitoring The Effectiveness Of Wildlife Exits And Bobcat Use Along A South Texas Highway, Jamie E. Langbein
Theses and Dissertations
Roadside exclusion fencing is commonly used to mitigate wildlife road mortalities and property damages caused by wildlife-vehicle collisions. A potential consequence is that animals may become trapped on the road by fencing. On State Highway 100 in South Texas, the Texas Department of Transportation installed ten wildlife exits (WE) allowing animals to exit the roadway through a modified opening in the fence. However, some individuals used the WE to access the roadway. In this study, a new design was implemented, with narrower openings, a ramp and a clear plastic one-way door. While the updated design prevented road access for wildlife, …
Climate Change And The Shifting Geography Of Coral-Reef Development, Victor Rodriguez-Ruano
Climate Change And The Shifting Geography Of Coral-Reef Development, Victor Rodriguez-Ruano
Theses and Dissertations
Coral-reef development is modulated by growth processes that deposit calcium carbonate onto the reef, such as calcification, and destructive processes that remove calcium carbonate from the reef, such as bioerosion. Wherever calcification rates exceed bioerosion rates, there is a net accretion of the reef through time, but where bioerosion rates exceed calcification rates, there is a net destruction of the reef through time. A reef’s framework is the legacy of the interaction of these processes throughout a reef’s history. Studying the fossil frameworks of reefs can shed light on the environmental factors that have controlled reef development in the past, …
Overexpression Of Ubtf Correlates With Aggressive Phenotypes Of Prostate Cancer Cells, Guillermo Andres Saldana
Overexpression Of Ubtf Correlates With Aggressive Phenotypes Of Prostate Cancer Cells, Guillermo Andres Saldana
Theses and Dissertations
Prostate cancer (PrCa) is one of the most common malignancies in men globally and the second leading cause of cancer associated deaths in developed countries. Accumulating evidence have demonstrated involvement of various molecular and cellular factors in the development, progression and chemoresistance of PrCa and many of them were successfully established as potential molecular targets for therapy. Despite these advancements, the underlying mechanisms of PrCa occurrence is still unclear, which limits the diagnosis and therapy. Therefore, it is an urgent need to discover potential molecular targets which can be used in rational design of new strategies for the prevention and …
Aedes Aegypti Host Preference On Canines Versus Human Volatile Skin Compounds, Melissa Bernadette Rosalez
Aedes Aegypti Host Preference On Canines Versus Human Volatile Skin Compounds, Melissa Bernadette Rosalez
Theses and Dissertations
It is critical to understand how Aedes aegypti mosquitoes detect hosts through cues such as volatile skin compounds. In South Texas, evidence suggests that this mosquito is showing a feeding preference for canines over humans. This shift may impact the transmission of Dirofilaria immitis, canine heart worms, in local dog populations. Our study is set to explore Ae. Aegypti attraction to hosts using canine and human volatile compounds. Volatile skin compounds will be collected using a volatile collection system. Compounds will be analyzed using gas chromatography/mass spectrometry. It is anticipated that the main volatile skin compounds amongst humans are nonanal, …
Growth Rates, Morphology, And Potential For Mariculture Of The Southern Population Of Crassostrea Virginica In The Lower Laguna Madre, Texas, Jerad Lee Fuelling
Growth Rates, Morphology, And Potential For Mariculture Of The Southern Population Of Crassostrea Virginica In The Lower Laguna Madre, Texas, Jerad Lee Fuelling
Theses and Dissertations
The Eastern Oyster also known as Crassostrea virginica, is an important resource here in the United States. Historically, this species has been overfished, poorly managed, and plagued by disease. Oyster mariculture is a growing industry here in the United States and is a sustainable solution to producing oysters. Texas has become the last coastal state to legalize oyster mariculture which means there is now a vast coastline with many unique bay systems that are open to this industry. One bay system that is particularly unique is the Lower Laguna Madre which is a hypersaline lagoon. Little is known about …
Effects Of Short-Term Pesticides Exposure On Swimming Behavior, Tissue Morphology, Oxidative-Nitrative Stress, Antioxidant Expression, And Cellular Apoptosis In Kidneys Of Goldfish, Esmirna Cantú
Theses and Dissertations
The prevalence of pesticides in the aquatic environment continues to increase due to anthropogenic activities and poses a threat to aquatic organisms. The aim of this study was to determine the short-term exposure (one-week) of pesticide mixtures (metolachlor, linuron, isoproturon, tebucanazole, alconifen, atrazine, pendimethalin; azinphos-methyl) on swimming behaviors, kidney morphology, and expression of nitrotyrosine protein (NTP), dinitrophenyl protein (DNP), superoxide dismutase (SOD), catalase (CAT), renin, and cellular apoptosis in goldfish (Carassius auratus). Results indicated that both low- and high-dose pesticide mixtures decreased the distance swimming behavior. Histological analysis showed pesticide exposure alters kidney morphology. DNP, NTP, and renin expressions, and …
Chemical Investigation Of Dichloromethane Extract Of Aloe Vera Peels: An Agricultural Waste, Nazmul Huda
Chemical Investigation Of Dichloromethane Extract Of Aloe Vera Peels: An Agricultural Waste, Nazmul Huda
Theses and Dissertations
Aloe barbadensis Miller, commonly called Aloe Vera, is a widely popular succulent plant species cultivated across subtropical regions worldwide from India to the Tex-Mex border. Besides its historical uses, Aloe juice has garnered attention as a potential remedy for various ailments, particularly in treating various skin conditions and facilitating wound recovery, including obesity, diabetes, hepatitis, Crohn's disease, and ulcerative colitis. Regrettably, the agricultural practice following sap extraction involves discarding Aloe vera peels, constituting agricultural waste. As part of our continuous research on extraction, isolation, separation, and spectral characterization of value-added chemicals present in waste botanicals herein, …
Age-Related Oligodendrocyte Lineage And Learning Abnormalities Driven By Nf1 Mutation In Mice, Saul Lopez
Age-Related Oligodendrocyte Lineage And Learning Abnormalities Driven By Nf1 Mutation In Mice, Saul Lopez
Theses and Dissertations
Neurofibromatosis Type 1 (NF1) is an autosomal dominant disease caused by mutations in the NF1 gene, on chromosome 17. NF1 patients suffer from a number of neurological issues including learning deficits and increased risk of age-related dementia. Additionally, NF1 patients present with multiple white matter and myelin abnormalities. Whether and how myelin abnormalities impact learning in NF1 is not known; therefore, we aimed to gain insights on potential links between Nf1 mutation and learning issues Unpublished data indicate that NF1 female-but not male- mice with Nf1+/- germline mutation show defects in a myelin-regulated learning/memory test (the complex wheel; CW) at …
The Relationship Between Biofouling Adhesion And Frequency Of Mechanical Cleaning To Control The Recruitment To Clear Coatings, Dylan Thomas Eggers
The Relationship Between Biofouling Adhesion And Frequency Of Mechanical Cleaning To Control The Recruitment To Clear Coatings, Dylan Thomas Eggers
Theses and Dissertations
There is a need to control biofouling on sensors and transparent windows in the marine environment. Clear silicone coatings offer a method to reduce the adhesion strength of marine organisms to the surface, however, these also require mechanical cleaning to maintain the surfaces free of fouling. This research evaluated the performance of eighty seven formulations and took the top two candidates to investigate a) the frequencies of wiping required by a brush to maintain two coatings and uncoated glass surfaces free of fouling and b) the effects of clear silicone coatings fouling release properties on required frequencies. The panels were …
Rage In Chronic Pulmonary Inflammation And Obstetric Complications, Katrina Lynn Curtis
Rage In Chronic Pulmonary Inflammation And Obstetric Complications, Katrina Lynn Curtis
Theses and Dissertations
The receptor for advanced glycation end-products (RAGE) is a transmembrane cell surface protein of the immunoglobulin superfamily that acts as part of both the innate and adaptive immune system. RAGE is highly expressed in lung tissue and is therefore of interest in the pulmonary immune response. Specifically, RAGE mediates several cell-signaling responses such as inflammation and apoptosis. This work sought to elucidate the role of RAGE in the setting of chronic pulmonary irritation such as that found in long-term exposure to secondhand smoke (SHS). This irritation has several shared characteristics with lung diseases such as chronic obstructive pulmonary disease (COPD) …
Mechanisms, Evolution, And Rapid Diagnosis Of Carbapenem Resistance, Taalin Shale Hoj
Mechanisms, Evolution, And Rapid Diagnosis Of Carbapenem Resistance, Taalin Shale Hoj
Theses and Dissertations
An estimated 70% of bacterial infections in the United States are resistant to first-line antibiotics. Of these, among the most difficult to treat are highly resistant to carbapenems, an antibiotic class used as a last resort. Septicemia, particularly when caused by a carbapenem-resistant organism, is among the most challenging clinical scenarios to treat, with an overall mortality rate of carbapenem-resistant septicemias 63.8%. Encouragingly, if effective antimicrobial treatment begins within 1-3 hours of septic shock onset, patient survival rates are around 80%. The first section of this work describes a real-time PCR-based assay that when coupled with existing bacteria-blood separation technology, …
Elucidating The Architecture Of The Tclijn Complex That Converts Cysteine To Thiazoles In The Biosynthesis Of Micrococcin, Diana G. Calvopina Chavez
Elucidating The Architecture Of The Tclijn Complex That Converts Cysteine To Thiazoles In The Biosynthesis Of Micrococcin, Diana G. Calvopina Chavez
Theses and Dissertations
Thiopeptides are a family of antimicrobial peptides that are characterized for having sulfur-containing heterocycles, and for being highly post-translationally modified. Numerous thiopeptides have been identified; almost all of which inhibit protein synthesis in gram-positive bacteria. These intrinsic antimicrobial properties make thiopeptides promising candidates for the development of new antibiotics. The antimicrobial peptide micrococcin is a thiopeptide that is synthesized by the ribosome and undergoes several post-translational modifications (PTMs). Micrococcin is formed from a precursor peptide, TclE. TclE comprises an N-terminal leader (35-AA) that is crucial for recognition of the PTM machinery, alongside a C-terminal core sequence (14-AA) that undergoes multiple …
Evolutionary Conservation And Times Of Action Of Heterochronic Genes, Maria Ivanova
Evolutionary Conservation And Times Of Action Of Heterochronic Genes, Maria Ivanova
Theses and Dissertations
The heterochronic pathway of C. elegans is the most well-characterized system to date for controlling the sequence and timing of developmental events. However, we still have critical unanswered questions to address. First, little is known about the evolution of the heterochronic pathway, and of developmental timing in general. To determine if the roles of major heterochronic genes are conserved, I made mutants in orthologs of these genes in C. briggsae, using CRISPR/Cas9. My studies revealed a significant drift in the roles of some of the genes, although all of them are still involved in the developmental timing regulation, and several …
Manipulating And Assaying Chromatin Architecture Around Enhancer Elements In Vivo, John Lawrence Carter
Manipulating And Assaying Chromatin Architecture Around Enhancer Elements In Vivo, John Lawrence Carter
Theses and Dissertations
There are about 20,000 genes in the human genome. The lowly nematode worm, C. elegans, has about the same number of genes. How could two organisms that are so different arise from a similar number of genes? The answer is epigenetics, or the factors that help control when and where genes are expressed. There are many layers that comprise the epigenetic control of genes. One of which is the structure or architecture of chromatin. Chromatin is a complex of DNA and proteins. Histone proteins with DNA wrapped around them form the fundamental component of chromatin, the nucleosome. Chromatin exists in …
Cell Of Origin Identification Using Methylation Signatures From Seminal Cell-Free Dna And Heterogenous Cellular Mixtures, Ryan Barney
Theses and Dissertations
Infertility is an issue for approximately 12% of couples attempting to have a child. Of this group, 50% of the cases are due to male factor infertility. There are many reasons for decreased fecundity in men, but there remains 10% to 15% of infertile men that are diagnosed with the most severe form of infertility, non-obstructive azoospermia (NOA). A diagnosis of NOA implies the lack of sperm cells in the ejaculate with no physiological reason. The current diagnostic test and treatment consist of microscopic examination of seminal fluid and a biopsy to extract any viable sperm from the testis. This …
Dynamic Regulation Of Store-Operated Calcium Entry By Protein S-Acylation, Goutham Kodakandla
Dynamic Regulation Of Store-Operated Calcium Entry By Protein S-Acylation, Goutham Kodakandla
Theses and Dissertations
Calcium plays a pivotal role in many physiological functions in cells. Cytosolic calcium levels are finely tuned by calcium ion channels, pumps, and intracellular organelles. Store-operated calcium entry (SOCE) is when depletion of endoplasmic reticulum (ER) calcium stores activates a calcium sensor known as stromal interaction molecule 1 (STIM1). Activation of STIM1 leads to a conformational change from a compact state to an extended state. This extended state of STIM1 allows it to bind to a calcium channel in the plasma membrane (PM) known as Orai1. The binding of Orai1 and STIM1 leads to opening of Orai1 channels and calcium …
Changes In Rna Expression Of Hut78 Cells Resulting From The Hiv-1 Viral Protein R R77q Mutation, Joshua S. Ramsey
Changes In Rna Expression Of Hut78 Cells Resulting From The Hiv-1 Viral Protein R R77q Mutation, Joshua S. Ramsey
Theses and Dissertations
Human immunodeficiency virus type 1 (HIV-1) is the causative virus for acquired immunodeficiency syndrome (AIDS). AIDS is characterized by chronic inflammation and reduction of CD4+ T-cells in the blood. This leads to the patient becoming immunocompromised and much more susceptible to disease in general. Different phenotypes in the progression of AIDS have been observed in patients in either progressing to AIDS faster as a Rapid Progressor (RP), or slower as a Long-Term Non-Progressor (LTNP). Researching elements that result in the LTNP phenotype is of interest as it has the potential to offer alternative treatments and therapies to those suffering from …
The Effects Of A High-Carbohydrate Versus A High-Fat Shake On Biomarkers Of Metabolism And Glycemic Control When Used To Interrupt A 38-Hour Fast: A Randomized Crossover Study, Landon S. Deru
Theses and Dissertations
Purpose: The primary aim of this study was to determine the impact of various fast-interrupting shakes on markers of glycemic control including glucose, β-hydroxybutyrate (BHB), insulin, glucagon, GLP-1, and GIP. Methods: Twenty-seven adults (12 female, 15 male) completed all three conditions of this study. One condition consisted of a 38-hour water-only fast, and the other two conditions were similar but the fasts were interrupted at 24 hours by either a high carbohydrate/low fat (HC/LF) or a low carbohydrate/high fat (LC/HF) shake. Results: The water only fast resulted in 135.3% more BHB compared to the HC/LF condition (t = 7.77, p < 0.0001) and 69.6% more compared to the LC/HF condition (t = 5.12, p < 0.0001). Conversely, the LC/HF condition exhibited a 38.8% higher BHB level than the HC/LF condition (t = 2.70, p = 0.0086). Additionally, the area under the curve (AUC) for glucose was 14.2% higher in the HC/LF condition than in the water condition (t = 6.23, p < 0.0001) and 6.9% higher compared to the LC/HF condition (t = 3.14, p = 0.0024), with the LC/HF condition yielding 7.8% more glucose than the water condition (t = 3.21, p = 0.0020). At the 25-hour mark, insulin and glucose-dependent insulinotropic polypeptide (GIP) were significantly elevated in the HC/LF condition compared to the LC/HF condition (F = 3.84, p = 0.0002 and F = 2.27, p = 0.0244, respectively) and compared to the water condition (F = 7.00, p < 0.0001 and F = 9.96, p < 0.0001, respectively). Furthermore, insulin, glucagon-like peptide-1 (GLP-1), and GIP were increased in the LC/HF condition compared to the water condition at 25 hours (F = 3.19, p = 0.0016, F = 2.43, p = 0.0158, and F = 12.13, p < 0.0001, respectively). Notably, glucagon concentrations at the 25-hour mark decreased in the HC/LF group compared to the LC/HF condition (F = 3.37, p = 0.0009). However, by the 38-hour time point, no statistically significant differences were observed among the conditions for any of the analyzed hormones. Conclusions: While a LC/HF shake does not mimic a fast completely, it does preserve some of the metabolic changes including elevated BHB and glucagon, and decreased glucose and insulin compared to a HC/LF shake.
Quantification Of The Internalization Of A Commercially Available Silver Nanoparticle To The Bacterium Escherichia Coli, Samantha Mcneal Case
Quantification Of The Internalization Of A Commercially Available Silver Nanoparticle To The Bacterium Escherichia Coli, Samantha Mcneal Case
Theses and Dissertations
Nanoparticles (NPs), materials with dimensions ranging from 1 to 100 nanometers, are widely used in various consumer products, with silver nanoparticles (AgNPs) being the most prominent. Exposure to AgNPs occurs through multiple sources, including food packaging, supplements, and disinfectants, owing to their antimicrobial properties. Prior research has identified adverse health effects, such as cytotoxicity, toxicity, and Ag bioaccumulation resulting from AgNP exposure to bacteria in biological systems and the environment. However, most studies employ pristine, highly concentrated NPs, which may not accurately represent realistic exposure scenarios at environmentally relevant concentrations. This project investigates the fate and internalization of AgNPs, found …
Infection Intensity And Prevalence From Perkinsus Marinus In The Eastern Oyster, Crassostrea Virginica (Gmelin 1791) And Their Association With Salinity, Temperature, And Sex In South Carolina Estuaries, Deja E. Best
Theses and Dissertations
This project aimed to identify the associations between the infection intensity and prevalence of Perkinsus marinus infection (i.e., Dermo ) in the Eastern oyster, Crassostrea virginica (Gmelin), with extrinsic environmental factors such as changes in salinity and temperature along with oyster host factors such as sex ratio. The objectives of the study were to: (1) identify significant associations between the dependent variables, P. marinus prevalence and infection intensity, in relation to salinity and water temperature which may be affected by climate change; and (2) identify any intrinsic factors related to sex (i.e., male, female, intersex, and indeterminant) that may affect …
Replenishment Of Essential Natural Resources: An Assessment Of The Ability Of Freshwater Algae To Enhance Crop Quality And Soil Health, Lala Christina Ek
Replenishment Of Essential Natural Resources: An Assessment Of The Ability Of Freshwater Algae To Enhance Crop Quality And Soil Health, Lala Christina Ek
Theses and Dissertations
Disregard for soil, an essential natural resource, hinders global food production. Food insecurity is a major concern for both public health officials and environmental scientists due to soil quality decline, pollution, and climate change. Alternatives or targeted additions to chemical fertilizers can bolster soil quality, improve crop yields, lengthen crop shelf life, and mitigate environmental pollution. One potential alternative to chemical fertilizers is replacement of them with biological soil amendments, including algae, to enhance crop growth and improve soil health. Research was conducted at the University of South Carolina-Columbia campus garden to determine impacts of non-toxic freshwater algae on crop …
Application Of Computational Tools To Identify Variations Associated With Peromyscus Dominant Spot, Zhenhua Shang
Application Of Computational Tools To Identify Variations Associated With Peromyscus Dominant Spot, Zhenhua Shang
Theses and Dissertations
Peromyscus are the most prevalent mammalian species in North America, and they're employed extensively in both laboratory and field studies. P. maniculatus and P. polionotus, the deer mouse and the old-field mouse, are closely related and can produce viable and fertile hybrid offspring. However, a comprehensive database of polymorphisms, particularly in those kept as living stocks and supplied to university researchers, is lacking. In chapter 2, we performed comparative genomic study on P. maniculatus and P. polionotus and used the polymorphic data to identify the range of genetic complexity that underlies physiological and behavioral differences between two species. We also …
Causes And Consequences Of The Risk Of Generalizability Biases In Health Behavioral Interventions, Lauren Von Klinggraeff
Causes And Consequences Of The Risk Of Generalizability Biases In Health Behavioral Interventions, Lauren Von Klinggraeff
Theses and Dissertations
Preliminary testing of health behavior interventions (e.g., pilot, feasibility studies) are used to evaluate intervention viability prior to additional testing and resource investment (e.g., larger trials). This initial testing provides valuable information, but promising estimates of effectiveness produced during early testing are rarely reproduced in larger studies, stalling the development of effective, scalable health interventions. In the obesity intervention literature, external validity biases, features of the intervention that are not (or cannot) transfer to the larger study, are associated with these diminished effects. These study features, such who delivers the intervention, the characteristics of the population receiving the intervention or …
The Effect Of Antibiotics On Immune Cell Infiltration Of Colon In A Mouse Model Of Early Onset Colorectal Cancer, Valerie Hinsch
The Effect Of Antibiotics On Immune Cell Infiltration Of Colon In A Mouse Model Of Early Onset Colorectal Cancer, Valerie Hinsch
Theses and Dissertations
Early onset colorectal cancer (EOCRC) is an aggressive form of colorectal cancer diagnosed before the age of 50. While colorectal cancer cases in patients 50 years and older have been declining, EOCRC cases have been steadily increasing globally in the last few decades, and the cause is unknown. Many agents, called exposomes, have been associated with EOCRC based on their emergence and prevalence prior to and in parallel with the rise in EOCRC cases. Among these are antibiotics (Abx). Abx are indispensable in our fight against infectious diseases, however their overuse is becoming a global epidemic. They are prescribed globally, …
From Oceans To Public Health: Impact Of Climate Change And Socioecological Factors On Non-Cholera Vibrio Spp., Karlen Enid Correa Vélez
From Oceans To Public Health: Impact Of Climate Change And Socioecological Factors On Non-Cholera Vibrio Spp., Karlen Enid Correa Vélez
Theses and Dissertations
Climate change-induced stressors, such as temperature, salinity, pH, and wildfire, are contributing factors to the increase in frequency of Vibrio infections, altering Vibrio geographical constraints. At the same time, the expansion of the coastal population is resulting in increased input of treated municipal wastewater into areas that are also experiencing Vibrio proliferation. Given that increases in ocean temperature and sea level coupled with increases in human activity in coastal waters support greater Vibrio-human interactions, it is important to examine factors and mechanisms within this socio-ecological coupled system that may further strengthen this interaction. This study aimed to better understand the …
Integrated Wastewater Surveillance For Sars-Cov-2 And Antibiotic Resistant Bacteria: Implications For Public Health And Environmental Management, Mirza Isanovic
Integrated Wastewater Surveillance For Sars-Cov-2 And Antibiotic Resistant Bacteria: Implications For Public Health And Environmental Management, Mirza Isanovic
Theses and Dissertations
While current technologies have inadvertently resulted in wastewater treatment plants (WWTPs) becoming major sources of global antibiotic resistance gene (ARG) dissemination, wastewater can be leveraged to provide vital community-level health information. This project examined both of these aspects through wastewater-based surveillance of SARS-CoV-2 and metagenomic analysis of specific ARGs collected from both activated sludge and bioaerosols. In this study, we investigated treatment steps between the influent and final treated effluent to identify the point at which viral RNA is below detection. Additionally, we examined air surrounding high turbulence treatment steps to test for the presence of SARS-CoV-2 RNA in WWTP-generated …
The Role Of Insulin Signaling In Controlling Oogenesis In Drosophila Melanogaster, Tancia W. Bradshaw
The Role Of Insulin Signaling In Controlling Oogenesis In Drosophila Melanogaster, Tancia W. Bradshaw
Theses and Dissertations
Adult stem cell activity responds to organismal nutrient status to maintain and support tissue homeostasis. Despite the intricate relationship between dietary input, adipose tissue and peripheral organ function, we are at the tip of the iceberg regarding our understanding of the cellular and molecular mechanisms underlying adipose communication to other tissues. The Drosophila ovary receives nutritional signals from the fat body with multiple nutrient-sensing pathways functioning in adipocytes to control distinct stages of oogenesis. Insulin/insulin-like growth factor signaling (IIS) within adult adipocytes remotely controls oocyte production at distinct stages of oogenesis. The PI3K/Akt1 axis in adipocytes promotes germline stem cell …
Transdisciplinary Approaches To Community Engagement, Research Translation And Science Communication Through Application Of The Socio-Environmental Report Card Process And Product In Murrells Inlet, South Carolina, Ekaterina Negodyaeva Altman
Transdisciplinary Approaches To Community Engagement, Research Translation And Science Communication Through Application Of The Socio-Environmental Report Card Process And Product In Murrells Inlet, South Carolina, Ekaterina Negodyaeva Altman
Theses and Dissertations
Public health and environmental sustainability are interlinked. Three pillars of sustainable development are society, environment, and economy are supported and reinforced by healthy populations. Balancing these values in a long-term vision and application requires active involvement of communities and stakeholders in decision-making process of management of environmental resources and personal health choices. Transdisciplinary sustainability science provides a framework for addressing complex issues in sustainability and generates actionable knowledge to link science and policy and involved stakeholders in the scientific process. Transdisciplinary research processes use co-design, co-production, and co-implementation framework to create and re-integrate useful knowledge into practice on a local …
Dephosphorylation Of Mpk6 And Mpk3 By Phosphatases Modulates Responses To Herbivory In Arabidopsis, Claire Teresa Hann
Dephosphorylation Of Mpk6 And Mpk3 By Phosphatases Modulates Responses To Herbivory In Arabidopsis, Claire Teresa Hann
Theses and Dissertations
As sessile organisms, plants rely on extracellular signals and chemical responses to defend against stressors. Extracellular stress signals inducing defense responses originate both from biotic or abiotic threats, and from products of tissue damage or hormones. In defense against herbivores, essential responses include rapid generation of jasmonic acid (JA) at the wound site, followed by the global expression of genes that impede digestion and growth. Early defense gene expression amplifies JA production, while later JA-responsive gene expression causes the accumulation of defense products. MAP kinase (MAPK) pathways play a central role in mediating the perception of self, non-self, and hormonal …
Fundamental Study Of Ionic Liquid Physicochemical Effects On Thermal Stability Of Model Biological Macromolecules, Austin Keith Clark
Fundamental Study Of Ionic Liquid Physicochemical Effects On Thermal Stability Of Model Biological Macromolecules, Austin Keith Clark
Theses and Dissertations
Ionic Liquids (ILs) are substances with a unique physical attribute compared to that of solid ionic salts. At room temperature, ILs are molten salts that have a variety of physical effects that can play a role in their impact on other molecules, as solvents or solutes. They can play the role of the solvent in a variety of applications, from biofuels to organic catalysis or as excipients in pharmaceutical formulations. These ILs have a desirable use as solvents due to their ability to be tunable substances. Changing the cation or anion of the IL causes a change in its physical …