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Articles 4111 - 4140 of 5010
Full-Text Articles in Life Sciences
Whole-Body Vibration Compared To Traditional Physical Therapy In Individuals With Total Knee Arthroplasty, Aaron W. Johnson
Whole-Body Vibration Compared To Traditional Physical Therapy In Individuals With Total Knee Arthroplasty, Aaron W. Johnson
Theses and Dissertations
The purpose of the present study was to compare total knee arthroplasty (TKA) rehabilitation with and without whole-body vibration (WBV) to 1) understand if WBV is a useful treatment during TKA rehabilitation to increase quadriceps strength and function, and 2) to investigate the effect of WBV on quadriceps voluntary muscle activation. Subject and Methods. Individuals post TKA (WBV n=8, control n=8) received physical therapy with and without WBV for four weeks. Quadriceps strength and muscle activation, function, perceived pain, and knee range of motion were measured. Results. No adverse side effects were reported in either group. There was a significant …
The Role Of Stat And The Jak/Stat Pathway In Mediating The Effects Of Interleukin-6 On Star Expression, Janae Strickland
The Role Of Stat And The Jak/Stat Pathway In Mediating The Effects Of Interleukin-6 On Star Expression, Janae Strickland
Theses and Dissertations
Cortisol, a hormone produced by a hormone produced by the adrenal gland, is responsible for many regulatory functions in the body. Cortisol release is mediated by adrenocorticotrophic hormone, or ACTH, through the hypothalamus-pituitary-adrenal or HPA axis. This HPA axis is the major release pathway used during acute stress, during which the levels of ACTH parallel those of cortisol. However, in states of chronic stress, the level of ACTH drops dramatically, while cortisol remains high. This study focuses on the pathway of cortisol release during these chronic stress states, specifically examining the role of IL-6 with respect to STATs and the …
The Relationship Between Maternal Employment And Children's Physical Activity, Michael Scott Parker
The Relationship Between Maternal Employment And Children's Physical Activity, Michael Scott Parker
Theses and Dissertations
The purpose of this study was to determine children's and parents' activity levels, examine the relationship between mothers' and children's mean step counts, and fathers' and children's mean step counts, and determine if there are differences in physical activity levels among children with mothers who work full time, work part time, or are not employed. Fifty-eight families participated in this 12-day study. Each family member wore a Walk4Life LS 2525 or a Walk4Life LS 2505 pedometer to measure daily step counts. Additionally, all participants completed the pedometer step count logs each night, and parents completed a short demographic form. In …
Fresh Water Ecology Unit For Secondary Education Science Courses, Eric L. Hyer
Fresh Water Ecology Unit For Secondary Education Science Courses, Eric L. Hyer
Theses and Dissertations
Science means “to know", a process for gaining knowledge and an understanding of the natural world. Students need to be involved in active learning. In other words, they must do science, not just hear about it. Good science encourages students to gain knowledge by doing science: observing, questioning, exploring, making and testing hypotheses, comparing predictions, evaluating data, and communicating conclusions. This unit plan is designed to incorporate the components of fresh water, ecology, water quality, and a class-wide science project. Each lesson addresses selected standards from the state core curriculum and has specific objectives that are tied to the learning …
Analyses Of Greater Sage-Grouse (Centrocercus Urophasianus) Translocation Release Methods And Chick Survival In Strawberry Valley, Utah, Jordan P. Hennefer
Analyses Of Greater Sage-Grouse (Centrocercus Urophasianus) Translocation Release Methods And Chick Survival In Strawberry Valley, Utah, Jordan P. Hennefer
Theses and Dissertations
Manuscript No. 1 Recent research has indicated that low nest success and juvenile survival of Greater Sage-Grouse may be responsible for population declines. Recent technological advances in micro-transmitters have made radio-telemetry studies on Sage-Grouse chicks more common. Radio-telemetry enables monitoring of individual chicks and broods during a critical period of their life history. The exact cause of low chick recruitment in Strawberry Valley has not been well understood. In 2006, a chick mortality study using micro-transmitters was initiated to (1) determine the causes of chick mortality, (2) calculate overall chick survival, (3) compare chick survival in the Strawberry Valley population …
Ecology Of Culturable Organisms At Rozel Point, Great Salt Lake, Utah, Emily Sarah Haws
Ecology Of Culturable Organisms At Rozel Point, Great Salt Lake, Utah, Emily Sarah Haws
Theses and Dissertations
The study of organisms from extreme environments is an emerging field of research with applications to multiple scientific areas. One of these extreme environments is Great Salt Lake (GSL), whose microbiology has yet to be extensively studied. This dynamic and unique environment offers an excellent opportunity to increase understanding of hypersaline ecology. Cultivation of microorganisms remains an important part of ecology research, as it is essential for understanding microbial physiology. We report here the culturing and characterization of isolates from Rozel Point, located on the northeastern shore of Great Salt Lake. This site was chosen because of the presence of …
The Role Of Prolactin In Ccl28 Regulation, Jennie Hyde
The Role Of Prolactin In Ccl28 Regulation, Jennie Hyde
Theses and Dissertations
Infants are born with naive immune systems, making them susceptible to a variety of infections. In order to protect the newborn infant it is important that mothers be able to pass protective IgA antibodies to their infants through breast milk. B cells that produce IgA enter the mammary tissue during lactation and secrete IgA into the milk. During pregnancy, the mammary tissue expresses high levels of chemokines, molecules that allow lymphocytes to selectively home to specific tissues. The chemokine CCL28 has been shown to be upregulated during both pregnancy and lactation, and is vital for the ability of IgA-producing B …
Techniques For Reclaiming Mined Lands With Native Plants, Maria Elena Melnechuk
Techniques For Reclaiming Mined Lands With Native Plants, Maria Elena Melnechuk
Theses and Dissertations
In this experiment I examined the role of mycorrhizae, seeding rate, and fertilizer in promoting growth of native plants at a reclaimed mine site in central Arkansas. Permanent field plots were established to examine effects of treatments on native plant cover, nonnative plant cover, and bare ground. By the final year of data collection, 18 native species had been newly established at the experimental site. Compared to plots without mycorrhizae, plots with mycorrhizae had significantly higher native plant cover in the first sampling year only. The addition of native seed was important—plots without added seed had significantly lower native plant …
The Effect Of 1,25-Dihydroxy Vitamin D3 On At1 Cell Receptor Expression In Human Iliac Artery Endothelial Cells (Hiaec), Jenny Thomas
The Effect Of 1,25-Dihydroxy Vitamin D3 On At1 Cell Receptor Expression In Human Iliac Artery Endothelial Cells (Hiaec), Jenny Thomas
Theses and Dissertations
The renin-angiotensin system (RAS) plays an important part in homeostasis through angiotensin IPs role as a vasoconstrictor. Defects in the renin angiotensin system can lead to hypertension, heart attack, and stroke (Weir, 1999). Studies have shown an inverse relationship between Vitamin D3 and blood pressure (Li et al., 2002). While studies have been performed on vitamin D's effect on renin expression, little is known about vitamin D's effect on the angiotensin II high-affinity type 1 (ATi) receptor. The hypothesis for this study was that human iliac artery endothelial cells (HIAEC) supplemented with 1,25-dihydroxy vitamin D3 will express less AT] receptor …
A Scent-Station Survey Of Medium-Size Mammals On The Callaway Preserve, Harris County, Georgia, Anna-Maria Giacobello
A Scent-Station Survey Of Medium-Size Mammals On The Callaway Preserve, Harris County, Georgia, Anna-Maria Giacobello
Theses and Dissertations
The objective of this project was to determine the relative abundance of medium- sized mammals on the Callaway Preserve in Harris County, Georgia, using the scent- station technique, to determine species preference in regard to habitat, to compare relative abundance of species in regard to habitat, and to compare habitats in terms of the species present. Thirty-six scent-stations were established on the property and monitored to observe the presence of coyotes, raccoons, armadillos, foxes, opossums, and skunks. Of the total number of visits to the scent-stations, 36.36 % were coyotes, 18.18% were foxes 22.73% were armadillos, and 22.73% were raccoons. …
Adaptations Of Five Pale-Type Grain Amaranth Accessions (Amaranthus Caudatus) And Five Ataco Or Sangorache Accessions (Amaranthus Hybridus) In The Cities Of Otavalo And Antonio Ante, Sixto Stalin Tuston Torres
Adaptations Of Five Pale-Type Grain Amaranth Accessions (Amaranthus Caudatus) And Five Ataco Or Sangorache Accessions (Amaranthus Hybridus) In The Cities Of Otavalo And Antonio Ante, Sixto Stalin Tuston Torres
Theses and Dissertations
This study was conducted in two locations: Pucará (2,413m above sea level) and Mojandita (2,922m above sea level), both of which are found in the province of Imbabura, Ecuador. The objectives of this study were to: characterize the morphological and agronomic traits as well as the overall quality of the ten amaranth accessions in this study; identify the accessions with the highest yield and biomass; determine the nutritional characteristics of the experimental accessions; and determine the cost of production of amaranth per hectare. The following null hypothesis was assumed: the agronomic and nutritional characteristics of the ten accessions in this …
Diluents For Cryopreservation Of Semen From Non-Woolly Llamas (Lama Glama), Franz Nicolas Bustos Fernández
Diluents For Cryopreservation Of Semen From Non-Woolly Llamas (Lama Glama), Franz Nicolas Bustos Fernández
Theses and Dissertations
The collection and preservation of llama semen is not a standardized procedure as it is in cattle. It has a number of complications that are mainly associated with the characteristics of the semen. In order to contribute to the knowledge of reproductive biology, we decided to evaluate the behavior of llama semen in relation to the different diluters in this study. This study was done at the National Germplasm Bank for Camelids which is part of the Ministry of Rural Development of Agriculture and Environment. The Ministry is located in the Agriculture Experiment Center of Condoriri which belongs to the …
Evaluation Of Hair Production In Angora Rabbits (Oryctolagus Cuniculus), Fed With Three Different Rations Of Reed In The Desaguadero Municipality - Department Of La Paz, Angel Sullca Mamani
Evaluation Of Hair Production In Angora Rabbits (Oryctolagus Cuniculus), Fed With Three Different Rations Of Reed In The Desaguadero Municipality - Department Of La Paz, Angel Sullca Mamani
Theses and Dissertations
This study was carried out in the Azafranal community of the Desaguadero municipality, which is in the Ingavi Province of the Department of La Paz. It was conducted at an altitude of 3350 meters above sea level at 16°20’00” south latitude and 69°00’00” west longitude. The study went from December 20, 2003 to June 20, 2004. Our objective was to evaluate hair production in angora rabbits (Oryctolagus cuniculus) fed with three different rations of reed. The experimental trial was done at the Angorita farm over a 135 day period that was divided into three smaller periods of 45 days. The …
The Vascular Flora Of Saline County, Arkansas, Charles Theodore Witsell
The Vascular Flora Of Saline County, Arkansas, Charles Theodore Witsell
Theses and Dissertations
The vascular flora of Saline County, Arkansas was collected from March 2002 to November 2007 resulting in a total of 1,510 taxa (52% of the known flora of Arkansas), representing 165 families, 617 genera, and 1,457 species. Of these, 241 (15.9%) are non-native and 99 (6.6%) are of state conservation concern. Of these, 20 taxa (1.3%) are considered to be of global conservation concern (G1-G3). Twenty-seven habitats and plant communities are qualitatively described from the county. Of these, shale barrens, igneous glades, pine flatwoods, swamp lakes and floatant marshes, channel scar depression ponds, high-gradient stream channels, and bluffs and talus …
Role Of Rok And Pkc In Permeabilized Rabbit Femoral Artery, Lyndsay Jacquelyn Clelland
Role Of Rok And Pkc In Permeabilized Rabbit Femoral Artery, Lyndsay Jacquelyn Clelland
Theses and Dissertations
Discoveries made with KCl-induced contractions have elucidated the more complex reactions involved in GPCRs signaling; once the mechanisms of smooth muscle Ca2+ sensitization and desensitization are fully understood, then the development of advanced treatments for vascular disorders such as hypertension, cerebral and coronary vasospasm, and vascular hyporeactivity following hemorrhagic shock may be possible. Studies have shown that KCl-induced contractions induce Ca2+-sensitization. Therefore, we tested the hypothesis that KCl induced Ca2+-sensitization is due to ROK activation by the increase in [Ca2+]i. To test this hypothesis, rabbit femoral arteries were permeabilized with 20µg/ml α-toxin and 1% Triton X-100 and subjected to different …
Corticular Photosynthetic Dynamics For A Coastal Evergreen Shrub: Myrica Cerifera, Jaclyn K. Vick
Corticular Photosynthetic Dynamics For A Coastal Evergreen Shrub: Myrica Cerifera, Jaclyn K. Vick
Theses and Dissertations
I quantified seasonal variations in corticular photosynthesis in 1st through 5th order branches of Myrica cerifera L. (Myricaceae) in order to determine whether corticular photosynthesis contributes to whole plant carbon gain by reducing respirational CO2 loss. Maximum % refixation was 110 ± 39 % of CO2 efflux in the dark (Rd) in 1st order branches during winter, minimum was 18 ± 3 % in 5th order branches during summer. Variations in % refixation paralleled changes in photosynthetically active radiation (PAR). As light attenuated with increasing branch order % refixation decreased. Increased PAR in the winter due to a more sparse …
The Role Of Sphingosine Kinase 2 In Cell Growth And Apoptosis, Heidi M. Sankala
The Role Of Sphingosine Kinase 2 In Cell Growth And Apoptosis, Heidi M. Sankala
Theses and Dissertations
Two isoforms of sphingosine kinase (SphK) catalyze the formation of sphingosine-1-phosphate (SIP). Whereas, SphKl stimulates cell growth and survival, it was found that when overexpressed in mouse NIH 3T3 fibroblasts SphK2 enhances caspase-dependent apoptosis in response to serum deprivation, independently of S1P receptors. Sequence analysis revealed that SphK2 contains a 9 amino acid motif similar to that present in BH3-only proteins. Studies showed that the BH3-only domain, catalytic activity, endoplasmic reticulum (ER) stress, and uptake of calcium by the mitochondria may all contribute to the apoptotic effects of overexpressed SphK2 in NIH 3T3 cells. Further studies in human carcinoma cells …
The Expression Of Neutrophil Products, Myeloperoxidase And Matrix Metalloproteinase 8, In Systemic Vasculature Of Obese And Preeclamptic Women, Juhi Shukla
Theses and Dissertations
Evidence shows the activation of neutrophils in the systemic vasculature of obese and preeclamptic women. In this study, I evaluated whether expression of neutrophil products, myeloperoxidase (MPO) and matrix metalloproteinase 8 (MMPS), was associated with neutrophil infiltration in systemic vascular tissue of obese and preeclamptic women. I tested my hypotheses by using immunohistochemical studies to look at the expression of MPO and MMP8 in the vasculature of obese and preeclamptic women. There was a significantly greater expression of MPO and MMP8 in the vasculature of preeclamptic women as compared to normal pregnant and normalnonpregnant women. The vasculature of obese women …
The Influence Of Adenoviral Infection And The Group Via Calcium-Independent Phospholipase A2 On Hepatic Lipid Metabolism, William Palmer Wilkins Iii
The Influence Of Adenoviral Infection And The Group Via Calcium-Independent Phospholipase A2 On Hepatic Lipid Metabolism, William Palmer Wilkins Iii
Theses and Dissertations
Sterol regulatory element-binding proteins (SREBP) are transcription factors that regulate genes involved in lipid metabolism especially in the liver. Therefore, hepatic SREBP is significant regulator of systemic lipid metabolism. Evidence demonstrates that insulin and dietary unsaturated fatty acid (UFA) regulate SREBP1 expression and subsequent SREBP1-mediated gene transcription, events that in many instances result in modulation of systemic fatty acid and triglyceride (TG) homeostasis. A series of investigations was designed to uncover novel regulators of SREBP1. Dietary and exogenous addition of UFA has been shown to regulate SREBP function yet, an endogenous source of UFA capable of modulating SREBP remains elusive. …
Effect Of The Consumption Of Farm Animals On The Diet And Hemoglobin Levels Of School Age Children In The Rural Communities Of Topo, Imbabura, Gualabi, Calpaqui, And Compania Of The Imbabura Province, Alexandra Echeverría
Theses and Dissertations
This research addressed malnutrition in the villages of Topo, Imbabura, Gualabí, Calpaquí and Compañía in the city Otavalo, which is in the Province of Imbaura, Ecuador. The research determined the effects of consumption of small-animals on the diet and hemoglobin levels in school aged boys and girls. This study involved 311 indigenous children between 6 and 12 years of age. Following parental authorization, blood tests and fecal samples were taken from each child to analyze hemoglobin and parasites. Additional information gathered from this study group included a socio-economic survey, frequency of food consumption, 24 hour inventory, animal production, and basic …
Evaluation Of The Nutritional Quality Of Twelve Species Of Grass Tolerant To Salt And Drought In Function To Their Dry Matter Accumulation Curve In The Tamborada Region, Julio César Bustamante Alavi
Evaluation Of The Nutritional Quality Of Twelve Species Of Grass Tolerant To Salt And Drought In Function To Their Dry Matter Accumulation Curve In The Tamborada Region, Julio César Bustamante Alavi
Theses and Dissertations
Currently, livestock production in the Andean highlands of Bolivia is done with low food efficiency due to the free range grazing system. This in turn leads to nutritional deficiencies. Therefore, it is necessary to substitute these grass species for others that fulfill nutritional requirements. Our main objective was to determine the species of grass with the best nutritional quality. Of the 12 species, only 11 were analyzed because the species Didtichlis stricta did not germinate. Five monthly samples were taken after the cut (ddc) at the following intervals: 50, 81, 112, 141, and 176 days. These samples were analyzed in …
Evaluation Of Vicuñas (Vicugna Vicugna) Fed With Three Types Of Hay In Stables In The Municipality Of Tiahuanaco, Department Of La Paz, José Cartagena Catacora
Evaluation Of Vicuñas (Vicugna Vicugna) Fed With Three Types Of Hay In Stables In The Municipality Of Tiahuanaco, Department Of La Paz, José Cartagena Catacora
Theses and Dissertations
This study was conducted in the Rural Academic Unit of Tiahuanaco, in the Ingavi province, in the department of La Paz. Three juvenile vicunas and three adult vicunas were used. Our objective was to observe the development of vicunas (Vicugna vicugna) fed with three types of hay (Bromus catharicus Phalaris tuberoisum and Medicago sativa) in stables. We obtained the following results: rectal temperature of 38.2ºC in juveniles and 38.6ºC in adults; heart rate of 68 beats/min in juveniles and 67 beats/min in adults; respiratory rate of 18 breaths/min in juveniles and 17 breaths/min in adults; femoral vein pulse of 70 …
Response Of Three Ecotypes Of Maca (Lepidium Meyenii Walp.) To Five Levels Of Ovine Manure In The Community Of Yampupata (Manco Kapac Province - La Paz), Sabina Quispe Paye
Response Of Three Ecotypes Of Maca (Lepidium Meyenii Walp.) To Five Levels Of Ovine Manure In The Community Of Yampupata (Manco Kapac Province - La Paz), Sabina Quispe Paye
Theses and Dissertations
This study was conducted in the community of Yampupata, in the municipality of Copacabana, in the Manco Kapac province, La Paz, to an altitude of 3841 m.a.s.l, agricultural campaign 2003-2004. The purpose of the study was to determine and compare the fenological stages (germination, growth, leafing, and harvesting), hypocotyl yield (dry and fresh), classification of the hypocotyl (diameter, length, etc.), and the economical evaluation as well. The experiment set up was installed in the lower region of the community, dedicated to agriculture, performing all the aforementioned activities together for the period of a year. The experimental design was of Random …
Addressing Issues In The Detection Of Gene-Environment Interaction Through The Study Of Conduct Disorder, Elizabeth Prom-Wormley
Addressing Issues In The Detection Of Gene-Environment Interaction Through The Study Of Conduct Disorder, Elizabeth Prom-Wormley
Theses and Dissertations
This work addresses issues in the study of gene-environment interaction (GxE) through research of conduct disorder (CD) among adolescents and extends the recent report of significant GxE and subsequent replication studies. A sub-sample of 1,299 individual participants/649 twin pairs and their parents from the Virginia Twin Study of Adolescent and Behavioral Development was used for whom Monoamine Oxidase A (MAOA) genotype, diagnosis of CD, maternal antisocial personality symptoms, and household neglect were obtained. This dissertation (1) tested for GxE by gender using MAOA and childhood adversity using multiple approaches to CD measurement and model assessment, (2) determined whether other mechanisms …
Role Of Ceramide-1-Phosphate As A Specific And Potent Activator Of Group Iva Cytosolic Phospholipase A2 Alpha, Preeti Subramanian
Role Of Ceramide-1-Phosphate As A Specific And Potent Activator Of Group Iva Cytosolic Phospholipase A2 Alpha, Preeti Subramanian
Theses and Dissertations
Eicosanoids are potent mediators of inflammatory response whose role has been well established in inflammatory disorders. Release of arachidonic acid by group IVA cytosolic phospholipase A2 α (cPLA2α) is the initial rate limiting step for the production of eicosonoids in response to inflammatory mediators. Previous findings from our laboratory have demonstrated that cPLA2α is directly activated by the emerging bioactive sphingolipid, ceramide-1-phosphate (C1P). In this study, we have developed a modified Triton X-100/phosphatidylcholine (PC) mixed micelle assay which was utilized to determine the kinetics and specificity of this lipid-enzyme interaction. Using this assay, the activity of the enzyme increased in …
Giant Pandas Balance Energy Budgets With Metabolic Depression: Insights From Radar Detection Of Heart Rates, Tommy Gene Finley
Giant Pandas Balance Energy Budgets With Metabolic Depression: Insights From Radar Detection Of Heart Rates, Tommy Gene Finley
Theses and Dissertations
Giant pandas ( Ailuropoda melanoleuca ) are flagship species for conservation because of their endangered status and charismatic nature. Giant pandas are placed in the bear family (Urisidae) within the order Carnivora. They specialize on a diet of bamboo, yet retain a typical carnivore gastrointestinal tract. Low energy digestive efficiency (9.5–34%) was calculated from bamboo-only digestibility trials conducted on captive giant pandas. Huge amounts of bamboo are consumed to overcome inefficient extraction and thus obtain sufficient energy and nutrients. I designed this study to gain insights into giant panda energy balance by measuring heart rates during sleep, their primary means …
Electrospun Blends Of Polydioxanone And Fibrinogen For Urological Applications, Joshua Ford Grant
Electrospun Blends Of Polydioxanone And Fibrinogen For Urological Applications, Joshua Ford Grant
Theses and Dissertations
The need for tissue and organ replacements cannot be satisfied by autograft and allografts alone. The purpose of this study was to investigate the feasibility of electrospinning a blend of polydioxanone and fibrinogen to produce an engineered tissue scaffold. Fiber diameter and pore size of blends were characterized, as well as mechanical strength. Cell proliferation assays for 1 and 7 day cultures were preformed, and a histological evaluation was performed to determine how favorable the various blends were to cell infiltration and proliferation. Some ratios of blends were identified that contained both acceptable mechanical properties and properties that facilitated cell …
Divergent Roles Of Pi3k And Akt In Rapamycin-Induced Cardioprotection Against Ischemia-Reperfusion Injury, Shivani Kirit Desai
Divergent Roles Of Pi3k And Akt In Rapamycin-Induced Cardioprotection Against Ischemia-Reperfusion Injury, Shivani Kirit Desai
Theses and Dissertations
Coronary heart disease (CHD) is one of the leading causes of death every year with nearly three-fourths of all deaths caused by the disease. The challenge scientists are facing today is discovering new drugs to protect the heart against cellular damage caused by ischemia-reperfusion injury (I-R injury). Rapamycin is one such drug that has been shown to protect the heart against ischemia-induced cellular injury. Rapamycin(sirolimus) inhibits protein synthesis through inhibition of the mammalian target ofrapamycin (mTOR). This property of rapamycin has led to its current clinical applications in drug-eluting stents and in immunosuppresive treatment to organ transplant patients. The mechanism …
Interleukin-10 Suppresses Mast Cell Ige Receptor Expression And Signaling In Vitro And In Vivo, Sarah B. Kennedy
Interleukin-10 Suppresses Mast Cell Ige Receptor Expression And Signaling In Vitro And In Vivo, Sarah B. Kennedy
Theses and Dissertations
Background: Mast cells are known for their role in allergy, asthma, and systemic anaphylaxis, and have been shown to play a role in inflammatory disease. Interleukin-10 can regulate inflammatory responses both in vitro and in vivo, and may be a natural regulator of mast cell activation.Objective: To examine Interleukin-10 mediated regulation of FcεRI expression and related downstream signaling molecules, and to determine how this affects mast cell function in vitro and in vivo.Methods: Mast cell FcεRI expression was evaluated with and without IL-10 treatment in human lung and skin mast cells, and on peritoneal mast cells from mice overexpressing IL-10 …
Investigation Of Age Related Differences In The Rewiring Of P2-Olfactory Receptor Neurons, Daniel Joseph Galante
Investigation Of Age Related Differences In The Rewiring Of P2-Olfactory Receptor Neurons, Daniel Joseph Galante
Theses and Dissertations
Olfactory receptor neurons (ORNs) maintain the ability to regenerate. These neurons reside in the olfactory epithelium and project axons that connect to the olfactory bulbs. Despite the diffuse distribution of ORNs in the olfactory epithelium, they converge at discrete glomeruli in the olfactory bulb. In the P2 IRES tau-lacZ mouse, the P2 ORN subtype has been previously mapped to two glomeruli, using X-gal staining. To determine if age affects ORN regeneration, left olfactory nerve transections were performed on P2 mice from immature (five-weeks old) and mature (1 6-weeks old) groups. Following recovery, the olfactory bulbs were processed to observe ORN …