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Articles 1051 - 1080 of 1571
Full-Text Articles in Life Sciences
Transcriptional Regulation Of The Heme Binding Protein Gene Family Of Bartonella Quintana Is Accomplished By A Novel Promoter Element And Iron Response Regulator, James M. Battisti, Laura S. Smitherman, Kate N. Sappington, Nermi L. Parrow, Rahul Raghavan, Michael F. Minnick
Transcriptional Regulation Of The Heme Binding Protein Gene Family Of Bartonella Quintana Is Accomplished By A Novel Promoter Element And Iron Response Regulator, James M. Battisti, Laura S. Smitherman, Kate N. Sappington, Nermi L. Parrow, Rahul Raghavan, Michael F. Minnick
Biological Sciences Faculty Publications
We previously identified a five-member family of hemin-binding proteins (Hbp's) of Bartonella quintana that bind hemin on the outer surface but share no homology with known bacterial heme receptors. Subsequently, we demonstrated that expression of the hbp family is significantly influenced by oxygen, heme, and temperature conditions encountered by the pathogen in the human host and the body louse vector; e.g., we observed a dramatic (>100-fold) increase in hbpC transcript levels in response to the "louse-like" temperature of 30 degrees C. The goal of the present study was to identify a transcription factor(s) involved in the coordinated and differential …
Hiv-2 Rna Dimerization Is Regulated By Intramolecular Interactions In Vitro, Tayyba T. Baig, Jean-Marc Lanchy, J. Stephen Lodmell
Hiv-2 Rna Dimerization Is Regulated By Intramolecular Interactions In Vitro, Tayyba T. Baig, Jean-Marc Lanchy, J. Stephen Lodmell
Biological Sciences Faculty Publications
Genomic RNA dimerization is an essential process in the retroviral replication cycle. In vitro, HIV-2 RNA dimerization is mediated at least in part by direct intermolecular interaction at stem-loop 1 (SL1) within the 5'-untranslated leader region (UTR). RNA dimerization is thought to be regulated via alternate presentation and sequestration of dimerization signals by intramolecular base- pairings. One of the proposed regulatory elements is a palindrome sequence ( pal) located upstream of SL1. To investigate the role of pal in the regulation of HIV-2 dimerization, we randomized this motif and selected in vitro for dimerization- competent and dimerization-impaired RNAs. Energy minimization …
High Rates Of Sulfate Reduction In A Low-Sulfate Hot Spring Microbial Mat Are Driven By A Low Level Of Diversity Of Sulfate-Respiring Microorganisms, Jesse G. Dillon, Susan Fishbain, Scott R. Miller, Brad M. Bebout, Kristen S. Habicht, Samuel M. Webb, David A. Stahl
High Rates Of Sulfate Reduction In A Low-Sulfate Hot Spring Microbial Mat Are Driven By A Low Level Of Diversity Of Sulfate-Respiring Microorganisms, Jesse G. Dillon, Susan Fishbain, Scott R. Miller, Brad M. Bebout, Kristen S. Habicht, Samuel M. Webb, David A. Stahl
Biological Sciences Faculty Publications
The importance of sulfate respiration in the microbial mat found in the low-sulfate thermal outflow of Mushroom Spring in Yellowstone National Park was evaluated using a combination of molecular, microelectrode, and radiotracer studies. Despite very low sulfate concentrations, this mat community was shown to sustain a highly active sulfur cycle. The highest rates of sulfate respiration were measured close to the surface of the mat late in the day when photosynthetic oxygen production ceased and were associated with a Thermodesuffiovibrio-like population. Reduced activity at greater depths was correlated with novel populations of sulfate-reducing microorganisms, unrelated to characterized species, and most …
Phylogeography Of The Thermophilic Cyanobacterium Mastigocladus Laminosus, Scott R. Miller, Richard W. Castenholz, Deana Pedersen
Phylogeography Of The Thermophilic Cyanobacterium Mastigocladus Laminosus, Scott R. Miller, Richard W. Castenholz, Deana Pedersen
Biological Sciences Faculty Publications
We have taken a phylogeographic approach to investigate the demographic and evolutionary processes that have shaped the geographic patterns of genetic diversity for a sample of isolates of the cosmopolitan thermophillic cyanobacterial Mastigocladus laminosus morphotype collected from throughout most of its range. Although M. laminosus is found in thermal areas throughout the world, our observation that populations are typically genetically differentiated on local geographic scales suggests the existence of dispersal barriers, a conclusion corroborated by evidence for genetic isolation by distance. Genealogies inferred using nitrogen metabolism gene sequence data suggest that a significant amount of the extant global diversity of …
Keeping Insects At Bay: Beyond Deet, Thomas P. Rooney
Keeping Insects At Bay: Beyond Deet, Thomas P. Rooney
Biological Sciences Faculty Publications
No abstract provided.
Comparison Of C. Elegans And C. Briggsae Genome Sequences Reveals Extensive Conservation Of Chromosome Organization And Synteny, Ladeana W. Hiller, Raymond D. Miller, Scott Everet Baird, Asif Chinwalla, Lucinda A. Fulton, Daniel C. Koboldt, Robert H. Waterston
Comparison Of C. Elegans And C. Briggsae Genome Sequences Reveals Extensive Conservation Of Chromosome Organization And Synteny, Ladeana W. Hiller, Raymond D. Miller, Scott Everet Baird, Asif Chinwalla, Lucinda A. Fulton, Daniel C. Koboldt, Robert H. Waterston
Biological Sciences Faculty Publications
To determine whether the distinctive features of Caenorhabditis elegans chromosomal organization are shared with the C. briggsae genome, we constructed a single nucleotide polymorphism-based genetic map to order and orient the whole genome shotgun assembly along the six C. briggsae chromosomes. Although these species are of the same genus, their most recent common ancestor existed 80-110 million years ago, and thus they are more evolutionarily distant than, for example, human and mouse. We found that, like C. elegans chromosomes, C. briggsae chromosomes exhibit high levels of recombination on the arms along with higher repeat density, a higher fraction of intronic …
Essential Elements Of A Defense-Review Of Dna Testing Results, Dan E. Krane
Essential Elements Of A Defense-Review Of Dna Testing Results, Dan E. Krane
Biological Sciences Faculty Publications
No abstract provided.
Proteomic And Immunoblot Analyses Of Bartonella Quintana Total Membrane Proteins Identify Antigens Recognized By Sera From Infected Patients, Jenni K. Boonjakuakul, Helen L. Gerns, Yu-Ting Chen, Linda D. Hicks, Michael F. Minnick, Scott E. Dixon, Steven C. Hall, Jane E. Koehler
Proteomic And Immunoblot Analyses Of Bartonella Quintana Total Membrane Proteins Identify Antigens Recognized By Sera From Infected Patients, Jenni K. Boonjakuakul, Helen L. Gerns, Yu-Ting Chen, Linda D. Hicks, Michael F. Minnick, Scott E. Dixon, Steven C. Hall, Jane E. Koehler
Biological Sciences Faculty Publications
Bartonella quintana is a fastidious, gram-negative, rod-shaped bacterium that causes prolonged bacteremia in immunocompetent humans and severe infections in immunocompromised individuals. We sought to define the outer membrane subproteome of B. quintana in order to obtain insight into the biology and pathogenesis of this emerging pathogen and to identify the predominant B. quintana antigens targeted by the human immune system during infection. We isolated the total membrane proteins of B. quintana and identified 60 proteins by two-dimensional sodium dodecyl sulfate-polyacrylamide gel electrophoresis and peptide mass fingerprinting. Using the newly constructed proteome map, we then utilized two-dimensional immunoblotting with sera from …
Climate, Hydrologic Disturbance, And Succession: Drivers Of Floodplain Pattern, Diane C. Whited, Mark S. Lorang, Mary J. Harner, F. Richard Hauer, John S. Kimball, Jack Arthur Stanford
Climate, Hydrologic Disturbance, And Succession: Drivers Of Floodplain Pattern, Diane C. Whited, Mark S. Lorang, Mary J. Harner, F. Richard Hauer, John S. Kimball, Jack Arthur Stanford
Biological Sciences Faculty Publications
Floodplains are among the world's most threatened ecosystems due to the pervasiveness of dams, levee systems, and other modi. cations to rivers. Few unaltered floodplains remain where we may examine their dynamics over decadal time scales. Our study provides a detailed examination of landscape change over a 60-year period ( 1945 - 2004) on the Nyack floodplain of the Middle Fork of the Flathead River, a free-flowing, gravel-bed river in northwest Montana, USA. We used historical aerial photographs and airborne and satellite imagery to delineate habitats ( i.e., mature forest, regenerative forest, water, cobble) within the. oodplain. We related changes …
An Extended Stem-Loop 1 Is Necessary For Human Immunodeficiency Virus Type 2 Replication And Affects Genomic Rna Encapsidation, Jean-Marc Lanchy, J. Stephen Lodmell
An Extended Stem-Loop 1 Is Necessary For Human Immunodeficiency Virus Type 2 Replication And Affects Genomic Rna Encapsidation, Jean-Marc Lanchy, J. Stephen Lodmell
Biological Sciences Faculty Publications
Genomic RNA encapsidation in lentiviruses is a highly selective and regulated process. The unspliced RNA molecules are selected for encapsidation from a pool of many different viral and cellular RNA species. Moreover, two molecules are encapsidated per viral particle, where they are found associated as a dimer. In this study, we demonstrate that a 10-nucleotide palindromic sequence (pal) located at the 3' end of the psi encapsidation signal is critical for human immunodeficiency virus type 2 (HIV-2) replication and affects genomic RNA encapsidation. We used short-term and long-term culture of pal-mutated viruses in permissive C8166 cells and their phenotypic reversion …
Bitopic Membrane Topology Of The Stable Signal Peptide In The Tripartite Junin Virus Gp-C Envelope Glycoprotein Complex, Sudhakar S. Agnihothram, Joanne York, Meg Trahey, Jack H. Nunberg
Bitopic Membrane Topology Of The Stable Signal Peptide In The Tripartite Junin Virus Gp-C Envelope Glycoprotein Complex, Sudhakar S. Agnihothram, Joanne York, Meg Trahey, Jack H. Nunberg
Biological Sciences Faculty Publications
The stable signal peptide (SSP) of the GP-C envelope glycoprotein of the Junin arenavirus plays a critical role in trafficking of the GP-C complex to the cell surface and in its membrane fusion activity. SSP therefore may function on both sides of the lipid membrane. In this study, we have investigated the membrane topology of SSP by confocal microscopy of cells treated with the detergent digitonin to selectively permeabilize the plasma membrane. By using an affinity tag to mark the termini of SSP in the properly assembled GP-C complex, we find that both the N and C termini reside in …
Filling Key Gaps In Population And Community Ecology, Anurag A. Agrawal, David D. Ackerly, Fred Adler, A. Elizabeth Arnold, Carla Cáceres, Daniel F. Doak, Eric Post, Peter J. Hudson, John L. Maron, Kailen A. Mooney, Mary Power, Doug Schemske, Jay Stachowicz, Sharon Strauss, Monica G. Turner, Earl Werner
Filling Key Gaps In Population And Community Ecology, Anurag A. Agrawal, David D. Ackerly, Fred Adler, A. Elizabeth Arnold, Carla Cáceres, Daniel F. Doak, Eric Post, Peter J. Hudson, John L. Maron, Kailen A. Mooney, Mary Power, Doug Schemske, Jay Stachowicz, Sharon Strauss, Monica G. Turner, Earl Werner
Biological Sciences Faculty Publications
We propose research to fill key gaps in the areas of population and community ecology, based on a National Science Foundation workshop identifying funding priorities for the next 5–10 years. Our vision for the near future of ecology focuses on three core areas: predicting the strength and context-dependence of species interactions across multiple scales; identifying the importance of feedbacks from individual interactions to ecosystem dynamics; and linking pattern with process to understand species coexistence. We outline a combination of theory development and explicit, realistic tests of hypotheses needed to advance population and community ecology.
Direct And Interactive Effects Of Enemies And Mutualists On Plant Performance: A Meta-Analysis, William F. Morris, Ruth A. Hufbauer, Anurag A. Agrawal, James D. Bever, Victoria A. Borowicz, Gregory S. Gilbert, John L. Maron, Charles E. Mitchell, Ingrid M. Parker, Alison G. Power, Mark E. Torchin, Diego P. Vázquez
Direct And Interactive Effects Of Enemies And Mutualists On Plant Performance: A Meta-Analysis, William F. Morris, Ruth A. Hufbauer, Anurag A. Agrawal, James D. Bever, Victoria A. Borowicz, Gregory S. Gilbert, John L. Maron, Charles E. Mitchell, Ingrid M. Parker, Alison G. Power, Mark E. Torchin, Diego P. Vázquez
Biological Sciences Faculty Publications
Plants engage in multiple, simultaneous interactions with other species; some (enemies) reduce and others (mutualists) enhance plant performance. Moreover, effects of different species may not be independent of one another; for example, enemies may compete, reducing their negative impact on a plant. The magnitudes of positive and negative effects, as well as the frequency of interactive effects and whether they tend to enhance or depress plant performance, have never been comprehensively assessed across the many published studies on plant–enemy and plant–mutualist interactions. We performed a meta-analysis of experiments in which two enemies, two mutualists, or an enemy and a mutualist …
Some Of The Problems Associated With Lcn (Low Copy Number) Testing, Dan E. Krane
Some Of The Problems Associated With Lcn (Low Copy Number) Testing, Dan E. Krane
Biological Sciences Faculty Publications
No abstract provided.
Run-Specific Limits Of Quantitation And Detection (An Alternative To Minimum Peak Height Thresholds), Dan E. Krane
Run-Specific Limits Of Quantitation And Detection (An Alternative To Minimum Peak Height Thresholds), Dan E. Krane
Biological Sciences Faculty Publications
No abstract provided.
Empirical Analysis Of The Str Profiles Resulting From Conceptual Mixtures, Dan E. Krane
Empirical Analysis Of The Str Profiles Resulting From Conceptual Mixtures, Dan E. Krane
Biological Sciences Faculty Publications
No abstract provided.
Assessing The Implications For Close Relatives In The Event Of Similar But Non-Matching Dna Profiles, Dan E. Krane
Assessing The Implications For Close Relatives In The Event Of Similar But Non-Matching Dna Profiles, Dan E. Krane
Biological Sciences Faculty Publications
No abstract provided.
Preliminary Notes On Tachinidae Reared From Lepidoptera In The Ecuadorian Andes, John O. Stireman Iii
Preliminary Notes On Tachinidae Reared From Lepidoptera In The Ecuadorian Andes, John O. Stireman Iii
Biological Sciences Faculty Publications
Current estimates of the species richness of Tachinidae among geographical provinces suggest that the Neotropical Region harbors the largest number of species and represents a geographic epicenter of tachinid diversification (O’Hara 2006). The Neotropics boasts an impressive fauna consisting of 2864 described species belonging to 822 genera at the time of the Neotropical catalog (Guimarães 1971), making it almost twice as species rich as any other geographic realm (O’Hara 2006; Stireman et al. 2006). This diversity is most apparent at middle elevations (1000– 2000m) along the mountain chains of tropical Central and South America, where tachinids are an abundant and …
Free-Living Male Mountain White-Crowned Sparrows Exhibit Territorial Aggression Without Modulating Total Or Free Plasma Testosterone, Sharon E. Lynn, Thomas P. Hahn, Creagh W. Breuner
Free-Living Male Mountain White-Crowned Sparrows Exhibit Territorial Aggression Without Modulating Total Or Free Plasma Testosterone, Sharon E. Lynn, Thomas P. Hahn, Creagh W. Breuner
Biological Sciences Faculty Publications
In some species, expression of territorial aggression is accompanied by a rise in testosterone secretion, but in others aggressive behavior is expressed while testosterone levels remain unchanged. Corticosteroid binding globulin (CBG) binds both corticosterone and testosterone in avian plasma. Thus, increasing corticosterone may result in fluctuations in unbound ("free") testosterone; this could result in greater biological activity of testosterone without an increase in testosterone secretion. We investigated whether such plasma interactions of testosterone, corticosterone, and CBG might result in alterations of free testosterone in male Mountain White-crowned Sparrows (Zonotrichia leucophrys oriantha). We conducted simulated territorial intrusions during incubation and compared …
Is Selectively Harvested Forest An Ecological Trap For Olive-Sided Flycatchers?, Bruce A. Robertson, Richard L. Hutto
Is Selectively Harvested Forest An Ecological Trap For Olive-Sided Flycatchers?, Bruce A. Robertson, Richard L. Hutto
Biological Sciences Faculty Publications
Disturbance-dependent species are assumed to benefit from forestry practices that mimic the appearance of postdisturbance landscapes. However, human activities that closely mimic the appearance but not the fundamental quality of natural habitats could attract animals to settle whether or not these habitats are suitable for their survival or reproduction. We examined habitat selection behavior and nest success of Olive-sided Flycatchers (Contopus cooperi) in a naturally occurring burned forest and an anthropogenically created habitat type-selectively harvested forest. Olive-sided Flycatcher density and nestling provisioning rates were greater in the selectively harvested landscape, whereas estimated nest success in selectively harvested forest was roughly …
Concordance Of Nuclear And Mitochondrial Dna Markers In Detecting A Founder Event In Lake Clark Sockeye Salmon, Kristina M. Ramstad, Carol Ann Woody, Chris Habicht, G. Kevin Sage, James E. Seeb, Fred W. Allendorf
Concordance Of Nuclear And Mitochondrial Dna Markers In Detecting A Founder Event In Lake Clark Sockeye Salmon, Kristina M. Ramstad, Carol Ann Woody, Chris Habicht, G. Kevin Sage, James E. Seeb, Fred W. Allendorf
Biological Sciences Faculty Publications
Genetic bottleneck effects can reduce genetic variation, persistence probability, and evolutionary potential of populations. Previous microsatellite analysis suggested a bottleneck associated with a common founding of sockeye salmon Oncorhynchus nerka populations of Lake Clark, Alaska, about 100 to 400 generations ago. The common founding event occurred after the last glacial recession and resulted in reduced allelic diversity and strong divergence of Lake Clark sockeye salmon relative to neighboring Six Mile Lake and Lake Iliamna populations. Here we used two additional genetic marker types (allozymes and mtDNA) to examine these patterns further. Allozyme and mtDNA results were congruent with the microsatellite …
Structural Basis Of Effector Regulation And Signal Termination In Heterotrimeric Galpha Proteins, Stephen R. Sprang, Zhe Chen, Xinlin Du
Structural Basis Of Effector Regulation And Signal Termination In Heterotrimeric Galpha Proteins, Stephen R. Sprang, Zhe Chen, Xinlin Du
Biological Sciences Faculty Publications
This chapter addresses, from a molecular structural perspective gained from examination of x-ray crystallographic and biochemical data, the mechanisms by which GTP-bound Galpha subunits of heterotrimeric G proteins recognize and regulate effectors. The mechanism of GTP hydrolysis by Galpha and rate acceleration by GAPs are also considered. The effector recognition site in all Galpha homologues is formed almost entirely of the residues extending from the C-terminal half of alpha2 (Switch II) together with the alpha3 helix and its junction with the beta5 strand. Effector binding does not induce substantial changes in the structure of Galpha*GTP. Effectors are structurally diverse. Different …
Causes And Consequences Of Prolonged Dormancy For An Iteroparous Geophyte, Silene Spaldingii, Peter Lesica, Elizabeth E. Crone
Causes And Consequences Of Prolonged Dormancy For An Iteroparous Geophyte, Silene Spaldingii, Peter Lesica, Elizabeth E. Crone
Biological Sciences Faculty Publications
1. Prolonged dormancy, during which a plant does not produce above-ground shoots during one or more growing seasons, is common in temperate herbaceous species, but its role in life history is poorly understood.
2. We analysed stage transitions to determine the consequences of prolonged dormancy for Silene spaldingii, a perennial geophyte of semi-arid grasslands in the Columbia Basin of western North America. We monitored 179 S. spaldingii plants from 1987 through 2005, and analysed demographic rates as a function of plant state and seasonal precipitation.
3. Dormant plants had similar survival and growth to vegetative plants, and were more …
Autoregulation Of Gld-2 Cytoplasmic Poly(A) Polymerase, Labib Rouhana, Marvin Wickens
Autoregulation Of Gld-2 Cytoplasmic Poly(A) Polymerase, Labib Rouhana, Marvin Wickens
Biological Sciences Faculty Publications
Cytoplasmic polyadenylation regulates mRNA stability and translation and is required for early development and synaptic plasticity. The GLD-2 poly(A) polymerase catalyzes cytoplasmic polyadenylation in the germline of metazoa. Among vertebrates, the enzyme is encoded by two isoforms of mRNA that differ only in the length of their 3′-UTRs. Here we focus on regulation of vertebrateGLD-2 mRNA. We show that the 3′-UTR of GLD-2 mRNA elicits its own polyadenylation and translational activation during frog oocyte maturation. We identify the sequence elements responsible for repression and activation, and demonstrate that CPEB and PUF proteins likely mediate repression in the resting oocyte. …
Amurocrangonyx, A New Genus Of Subterranean Amphipod (Crangonyctidae) From The Russian Far East, With A Redescription Of The Poorly Known Crangonyx Arsenjevi And Comments On Biogeographic Relationships, Dmitry A. Sidorav, John R. Holsinger
Amurocrangonyx, A New Genus Of Subterranean Amphipod (Crangonyctidae) From The Russian Far East, With A Redescription Of The Poorly Known Crangonyx Arsenjevi And Comments On Biogeographic Relationships, Dmitry A. Sidorav, John R. Holsinger
Biological Sciences Faculty Publications
Amurocrangonyx n. gen. is described on the basis of recently collected specimens of Crangonyx arsenjevi (Derzhavin, 1927), a very poorly known subterranean amphipod crustacean originally described from springs in the Khor River basin of the Ussury River drainage in the Russian Far East. The species is redescribed from specimens obtained from the type-locality, Orekhovy spring, and a neotype is designated. A careful examination of the newly acquired material, although closely similar morphologically to Crangonyx, suggests that it represents a new genus in Crangonyctidae. However, determination of the precise phylogeographic relationship of Amurocrangonyx to Crangonyx or to other crangonyctoid genera …
Conditions For Caribou Persistence In The Wolf-Elk-Caribou Systems Of The Canadian Rockies, Mark Hebblewhite, Jesse Whittington, Mark Bradley, Geoff Skinner, Alan Dibb, Clifford A. White
Conditions For Caribou Persistence In The Wolf-Elk-Caribou Systems Of The Canadian Rockies, Mark Hebblewhite, Jesse Whittington, Mark Bradley, Geoff Skinner, Alan Dibb, Clifford A. White
Biological Sciences Faculty Publications
Woodland caribou populations are considered threatened in Alberta and have declined in the Canadian Rocky Mountain National Parks of Banff and Jasper despite protection from factors causing caribou populations to decline outside of parks. Recent research emphasizes the importance of the numeric response of wolves to moose in moose-caribou-wolf systems to caribou persistence. Moose are rare in the Canadian Rockies, where the dominant ungulate prey for wolves is elk. Few studies have explored wolf-elk dynamics and none have examined implications for caribou. We used data collected in Banff to estimate the numeric response of wolves to elk from 1985 to …
Mutations In Transmembrane Domains 1, 4 And 9 Of The Plasmodium Falciparum Chloroquine Resistance Transporter Alter Susceptibility To Chloroquine, Quinine And Quinidine, Roland A. Cooper, Kristan D. Lane, Bingbing Deng, Jianbing Mu, Jigar J. Patel, Thomas E. Wellems, Xinzhuan Su, Michael T. Ferdig
Mutations In Transmembrane Domains 1, 4 And 9 Of The Plasmodium Falciparum Chloroquine Resistance Transporter Alter Susceptibility To Chloroquine, Quinine And Quinidine, Roland A. Cooper, Kristan D. Lane, Bingbing Deng, Jianbing Mu, Jigar J. Patel, Thomas E. Wellems, Xinzhuan Su, Michael T. Ferdig
Biological Sciences Faculty Publications
Mutations in the Plasmodium falciparum chloroquine (CQ) resistance transporter (PfCRT) can result in verapamil-reversible CQ resistance and altered susceptibility to other antimalarials. PfCRT contains 10 membrane-spanning domains and is found in the digestive vacuole (DV) membrane of intraerythrocytic parasites. The mechanism by which PfCRT mediates CQ resistance is unclear although it is associated with decreased accumulation of drug within the DV. On the permissive background of the P. falciparum 106/1(K76) parasite line, we used single-step drug selection to generate isogenic clones containing unique pfcrt point mutations that resulted in amino acid changes in PfCRT transmembrane domains 1 (C72R, K76N, K76I …
Tissue And Life Stage Distribution Of A Defensin-Like Gene In The Lone Star Tick Amblyomma Americanum, S. Michelle Todd, Daniel E. Sonenshine, Wayne L. Hynes
Tissue And Life Stage Distribution Of A Defensin-Like Gene In The Lone Star Tick Amblyomma Americanum, S. Michelle Todd, Daniel E. Sonenshine, Wayne L. Hynes
Biological Sciences Faculty Publications
The transcript sequence of the Amblyomma americanum Linnaeus (Acari: Ixodidae) defensin, termed amercin (amn), was ascertained and a 219-bp amn coding region identified. The gene encodes a 72-amino acid prepropeptide with a putative 37-amino acid mature peptide. This gene shows little similarity to either of the defensins from Amblyomma hebraeum Koch, the only other Amblyomma species for which a defensin has been described. Sequence comparisons with other tick defensins reveal amn to be shorter (6 bp or 2 amino acids) than the Ixodes scapularis Linnaeus (Acari: Ixodidae) and Dermacentor variabilis (Say) (Acari: Ixodidae) defensin sequences. The amercin prepropeptide …
An Epidemiological Model Of Rift Valley Fever, Holly D. Gaff, David M. Hartley, Nicole P. Leahy
An Epidemiological Model Of Rift Valley Fever, Holly D. Gaff, David M. Hartley, Nicole P. Leahy
Biological Sciences Faculty Publications
We present and explore a novel mathematical model of the epidemiology of Rift Valley Fever (RVF). RVF is an Old World, mosquito-borne disease affecting both livestock and humans. The model is an ordinary differential equation model for two populations of mosquito species, those that can transmit vertically and those that cannot, and for one livestock population. We analyze the model to find the stability of the disease-free equlibrium and test which model parameters affect this stability most significantly. This model is the basis for future research into the predication of future outbreaks in the Old World and the assessment of …
Structural Attributes Of The Hypogeous Holoparasite Hydnora Triceps Drège & Meyer (Hydnoraceae), Kushan U. Tennakoon, Jay F. Bolin, Lytton J. Musselman, Erika Maas
Structural Attributes Of The Hypogeous Holoparasite Hydnora Triceps Drège & Meyer (Hydnoraceae), Kushan U. Tennakoon, Jay F. Bolin, Lytton J. Musselman, Erika Maas
Biological Sciences Faculty Publications
The morphology of the hypogeous root holoparasite Hydnora triceps is highly reduced, and as with many holoparasites, the vegetative body is difficult to interpret. The vegetative body of H. triceps has been historically considered a "pilot root" studded with lateral appendages known as "haustorial roots." We found the vegetative body of H. triceps to consist of a rhizome with a thickened root-cap-like structure that covered a vegetative shoot apical meristem. From the apical meristem, procambial strands originated and developed into endarch collateral vascular bundles arranged radially around a pith without an interfascicular cambium. Xylem vessels had scalariform pitting and simple …