Life Sciences Commons^™

Increasing Swim Instructors' Perceived Knowledge Of Sensory-Based Strategies When Coaching Children Who May Have Sensory Differences, Gabrielle Palmer

UNLV Theses, Dissertations, Professional Papers, and Capstones

Although swim instructors are solely taught water safety regulations and correct swimming techniques, they are nonetheless viewed as mentors by the kids they work with. They are required to finish both their basic swim instructor (BSI) course and their cardiopulmonary resuscitation (CPR) certification, which primarily covers the fundamentals (American Red Cross Training Services, 2023; Kraft & Leblanc, 2018). However, neither provides a method of teaching swimming to children who might have sensory processing differences. This lack of education may affect both the child's participation and the swim instructor's capacity to impart knowledge. Research revealed that swim instructors are not very …

Plant-Plant Interaction In Early- Vs. Late-Successional Varieties Of The Hawaiian Landscape-Dominant Tree, Metrosideros Polymorpha, Tomoko Sakishima

UNLV Theses, Dissertations, Professional Papers, and Capstones

Plant-plant interactions play an important role in assembling plant communities. Interactions between neighboring plants can vary as a result of the genetic relatedness of neighbors, impacting rates of growth and patterns of resource allocation. When growing alongside close relatives, some species decrease their growth in a form of cooperation, while others grow faster through facilitation. A complication of plant interaction studies arises because decreased growth in the presence of close relatives can also be due to competition for resources, which increases with phenotypic similarity. Further complicating matters, mycorrhizal fungi, through their connections with plant roots, may strongly influence plant interactions. …

Quaternary Ammonium Compound Resistance Of Klebsiella Pneumoniae And Klebsiella Quasipneumoniae Strains Isolated From The International Space Station, Natasha Svetlana Sushenko

UNLV Theses, Dissertations, Professional Papers, and Capstones

The International Space Station (ISS) has been continuously inhabited for twenty-three years and harbors a diverse population of microorganisms under conditions of microgravity, elevated radiation, and relative isolation, including Biosafety Level 2 (BSL-2) opportunistic pathogens. To sanitize surfaces on the ISS, astronauts use a combination of four antimicrobial quaternary ammonium compounds (QACs). As the stresses of space flight are known to stimulate virulence and antimicrobial resistance in bacteria, the frequent use of QAC disinfectants on the ISS is of concern to NASA. This not only poses risks to astronauts during future long-term space travel, but there is also a concern …

Mixed Methods Approach To Assess ‘Placental Opioid-Enhancing Factor’ Activity Within ‘Alternative’ Health Contexts Of Human Maternal Placentophagy, Jacob C. White

UNLV Theses, Dissertations, Professional Papers, and Capstones

Rats with elevated opioid levels experience an even greater increase in pain threshold after placenta or amniotic fluid consumption via placental opioid-enhancing factor (POEF) in the afterbirth. POEF only enhances opioid hypoalgesia; it cannot produce hypoalgesia alone. Although the POEF molecule remains unidentified and its efficacy in humans is unknown, it could be a safe, novel pain treatment. People who consume placenta as an alternative postpartum health practice are ideal for testing POEF bioactivity. Though rat models show that bioactive POEF is highly sensitive, some forms of the practice in humans may conserve POEF.

This project is the first attempt …

Cellular Mechanisms Of Embryonic Eye Regrowth In Xenopus Laevis, Randolph L. Grell

UNLV Theses, Dissertations, Professional Papers, and Capstones

The African Clawed Frog, Xenopus laevis, has been an indispensable model organism for over 100 years in the study of embryogenesis and development. In recent years, this vertebrate model has emerged as a robust tool for deciphering the cellular and molecular mechanisms underlying various modes of tissue, limb, and organ regeneration. In the context of eye repair, Xenopus offers a unique model, where the adult frog eye has limited regenerative capacity compared to its pre-metamorphic embryonic and tadpole forms, which exhibit a robust capacity for regrowth. Understanding the intricate molecular mechanisms that underlie this developmental shift in regrowth ability …

Characterization Of Fibronectin Adhesion Isolated Dental Pulp Progenitor Cell Populations, Heoijin Kim

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: The DPSC constitutes a significantly small population, comprising approximately 1% of the total cells in the pulp tissue. Therefore, it is imperative to successfully culture and populate DPSCs in vitro before utilizing them for therapeutic purposes. Understanding DPSC heterogeneity is crucial for innovative regenerative therapies, prompting the investigation of mixed populations using fibronectin as a biological marker. It is reported that cellular phenotype and biological function may undergo alterations as cells replicate in a cultured environment or the substrate to which the cells adhere.

Objectives: In this study, we compared and analyzed the impact of various isolation methods on …

The Effect Of Transcranial Direct Current Stimulation Of The Dorsolateral Prefrontal Cortex On Muscle Fatigue Resistance, Taylie Thompson Liddell

UNLV Theses, Dissertations, Professional Papers, and Capstones

Transcranial direct current stimulation (tDCS) delivered to the dorsolateral prefrontal cortex (DLPFC) can increase endurance time in lower body cycling tasks. The purpose was to examine the effect of DLPFC-tDCS on the time to task failure (TTF) of a fatiguing contraction performed by hand muscles. The study used a double-blind, randomized, SHAM-controlled, crossover design. Participants completed two experimental sessions on separate days with a washout between sessions. All facets of the experiments were identical except the stimulation condition (DLPFC-tDCS or SHAM) that was given concurrent with the fatiguing contraction. The fatiguing contraction involved gripping a manipulandum with the index finger …

The Mitochondrial Membrane Potential As A Screening Tool For Immunostimulation, Kendra Mcglothen

UNLV Theses, Dissertations, Professional Papers, and Capstones

The rise of neuroinflammatory disorders highlights the importance of early detection and intervention for more effective treatment options. Neuroinflammation is associated with the pathogenesis of many neurological disorders, including Major Depressive Disorder, Alzheimer's disease, and Multiple Sclerosis. There has been a focus on neurons to advance our understanding of the underlying mechanisms of neuroinflammation and its role in neurodegeneration. However, recent studies have highlighted the pivotal role of glial cells, particularly microglia, in neuroinflammation due to their active participation in the immune response. This study investigates glial-specific indicators of morphology, metabolic changes, and drug efficacy in neuroinflammatory conditions. By analyzing …

Investigations Into The Relationship Between Menopause And Alzheimer’S Disease Pathology In A Mouse Model With Ovarian Follicle Depletion, Amanda M. Leisgang Osse

UNLV Theses, Dissertations, Professional Papers, and Capstones

Alzheimer’s Disease (AD) currently affects about 6.9 million Americans, with over two-thirds of those individuals being women. Interestingly, changes in the brain indicative of AD coincide with the onset of menopause. Post-menopausal women have significantly higher levels of AD pathologies, including amyloid beta and hyperphosphorylated tau, than pre-menopausal women. To investigate the relationship between AD pathologies and menopause, we induced menopause-like state in an AD mouse model, APP/PS1, by treatment with 4-vinylcyclohexene diepoxide (VCD) to accelerate ovarian follicle depletion. To monitor the transition to menopause, vaginal lavages and cytology was performed to determine if mice reached anestrous. Both female APP/PS1 …

A Low Dose Of Electro-Psychedelic Treatment Increases Neuronal Dendritic Arborization And Filopodic Spine Density, Elaine Aquino Vasquez

UNLV Theses, Dissertations, Professional Papers, and Capstones

Neuropsychiatric disorders remain a formidable challenge to the global healthcare system, necessitating innovative treatments to address their complex pathophysiology. Alternative therapeutic approaches, including electroconvulsive treatment (ECT) and psychedelics, have gained attention for their capacity to relieve a broad range of symptoms. ECT is a long-standing effective therapy for patients, especially treatment-resistant ones. Psychedelics, like psilocybin, can induce profound and sustained therapeutic effects. The limited understanding of their mechanisms of action, compounded by the negative stigma surrounding ECT and psilocybin, prevents them from being used as adjunct agents. ECT and psilocybin promote synaptic plasticity and modulate neural remodeling, yet their comparative …

Differential Expression Of Microrna Mir-145 And Mir-155 Downstream Targets In Oral Cancers Exhibiting Limited Chemotherapy Resistance, Conner Belnap

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background: New evidence has suggested that non-coding microRNAs play a significant role in mediating and modulating chemotherapy resistance, particularly among oral cancers. One recent study found that the expression of miR-145 and lack of miR-155 expression strongly correlated with a limited chemotherapy resistance to Cisplatin, 5-Fluorouracil and Paclitaxel , although the mechanism(s) responsible for these observations remain unidentified.

Methods: Using commercially available cell lines of oral squamous cell carcinoma (OSCC), RNA was isolated using phenol:chloroform extraction. The isolated RNA was converted into cDNA by reverse transcription and subsequently screened for the presence or absence of downstream targets of miR-145 and …

The Influence Of Dual Sources Cerebellar Transcranial Direct Current Stimulation On Muscle Fatigue, Janriek Asuncion Bognot

UNLV Theses, Dissertations, Professional Papers, and Capstones

Transcranial direct current stimulation (tDCS) applied unilaterally to the cerebellum (ctDCS) can improve several aspects of human motor performance. The purpose of the study was to examine the influence of dual source tDCS delivered bilaterally over the cerebellar cortices (dsc-tDCS) on the time to task failure (TTF) of a fatiguing contraction. The study utilized a double-blind, randomized, SHAM-controlled, within-subjects, crossover design and participants were given either dsc-tDCS or SHAM stimulation in two different experiments held 7 days apart. Every aspect of the two experiments was the same except the type of stimulation (dsc-tDCS or SHAM) delivered during the fatiguing contraction. …

Seasonal Climate And Environmental Conditions Associated With Physiological Variations Of Southwestern United States Pines, Taylor Brewer

UNLV Theses, Dissertations, Professional Papers, and Capstones

Juvenile and adult conifers in the southwestern United States are vulnerable to a range of different abiotic and biotic factors, yet it is unclear how their stress tolerance varies across environments. Predicted increases in the frequency and intensity of disturbance as well as greater climate and weather variability across the region highlight the potential for differential physiological responses across tree species and populations. This thesis focuses on two physiologic mechanisms, hydraulic vulnerability and mortality, that could be altered by climate change in two broadly distributed southwestern United States conifers: ponderosa pine and pinyon pine.

In chapter 2, I measured the …

The Influence Of Bihemispheric Transcranial Direct Current Stimulation On Muscle Fatigue, Ananya Singh Chauhan

UNLV Theses, Dissertations, Professional Papers, and Capstones

Unilateral transcranial direct current stimulation (tDCS) using two electrodes placed over the primary motor cortex (M1) and the contralateral supraorbital (SO) region (M1-SO montage) has been shown to decrease the progression of muscle fatigue. The primary purpose was to determine the impact of bihemispheric tDCS (bi-tDCS) applied over the left and right M1s (bi-tDCS) on the time to task failure (TTF) of a precision-grip task. The study implemented a double-blind, randomized, SHAM-controlled, within-subjects design. A total of 20 participants performed two experimental sessions (bi-tDCS and SHAM conditions) separated by a one-week washout. During each experimental session, a fatiguing isometric contraction …

Understanding Stress And Coping Among Adults In The United States During The Covid-19 Pandemic, Jocy-Anna Chevalier

UNLV Theses, Dissertations, Professional Papers, and Capstones

Since the COVID-19 pandemic started, individuals in the United States (U.S.) and across the globe have experienced unprecedented levels of stress. The purpose of this study is to understand the stress experienced among adults in the U.S. and which coping processes affect their overall emotional well-being. Guided by Lazarus and Folkman’s (1987) Transactional Model of Stress and Coping (TMSC), this study conducted a secondary data analysis (n=404) of adults across the U.S who completed an online survey examining their experiences with stress and coping. A Pearson correlation was utilized to explore the relationship between stress and depressive symptoms. Paired samples …

The Influence Of Bilateral Dual Source Transcranial Direct Current Stimulation On The Progression Of Muscle Fatigue, Eliza Clinton

UNLV Theses, Dissertations, Professional Papers, and Capstones

Transcranial direct current stimulation (tDCS) applied unilaterally to the primary motor cortex (M1) can significantly prolong the time to task failure (TTF) of a fatiguing contraction. The primary purpose of the study was to examine the influence of bilateral dual source tDCS (dstDCS) applied over the left and right M1s (ds-tDCS) on the TTF of a precision grip task. This was accomplished through the utilization of a double-blind, randomized, SHAM-controlled, within-subjects design. Fourteen participants completed two experiments (ds-tDCS and SHAM stimulation conditions) with a seven-day washout period between sessions. Each experiment involved the performance of a sustained isometric fatiguing contraction …

The Effect Of Dual Source Premotor Cortex Transcranial Direct Current Stimulation On Muscle Fatigue In Hand Muscles, Valentino Contini

UNLV Theses, Dissertations, Professional Papers, and Capstones

Single source transcranial direct current stimulation (tDCS) has been shown to increase the time to task failure (TTF) fatiguing contractions when applied to the dorsolateral prefrontal cortex (DLPFC) and to the primary motor cortex (M1). The primary purpose was to determine whether dual source tDCS delivered bilaterally over the premotor cortices (pmc-tDCS) could increase the TTF of a fatiguing contraction performed by hand muscles. A double-blind, randomized, SHAM-controlled, crossover design was used for this study with each participant performing two experimental sessions held on separate days a week apart. The only difference between the two sessions was the type of …

Regulation Of Embryonic Eye Regrowth In Xenopus Laevis, Dylan Guerin

UNLV Theses, Dissertations, Professional Papers, and Capstones

Regrowth of lost organs and tissues is an amazing ability that some animals possess. For regrowth to be considered full, the organism must regrow the organ or tissue to a state that is structurally and functionally similar to that which was lost. The ability of an organism to regrow lost or damaged tissue varies among animals, both in the mechanisms utilized to achieve regrowth, and in what body parts can be regrown. Potentially even closely related species can vary wildly in regenerative ability. Therefore, regenerative research can look to other tissues and organisms for direction in elucidating the mechanisms through …

Treatment Of Warthin’S Tumors Of The Parotid Gland With Radiofrequency Ablation: A Systematic Review Of The Current Literature, Kenny Do, Eric Kawana, Sisi Tian, Jo-Lawrence Bigcas

School of Medicine Faculty Research

Objective: Warthin’s tumors of the parotid gland can be safely observed. Definitive treatment usually requires parotidectomy under general anesthesia. The decision to operate on Warthin’s tumors of the parotid gland can be complicated in patients who wish to avoid risks of surgery and general anesthesia. This systematic review explores the potential of radiofrequency ablation (RFA) as a minimally invasive alternative. Methods: The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) model was used to collect 3 relevant studies that focused on RFA treatment for Warthin’s tumors. The cumulative averages for tumor size and cosmetic scores were then quantified for …

Establishing The Validity And Reliability Of The Astroskin® Biometric Shirt, Alex Macquarrie, Jasmin Sidhu, Chloe Deetlefs, Steve Whitfield, Matt Stainer

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 5: Issue 1, Article 4, 2024. Biometric garments such as the Astroskin® biometric shirt (Carre Technologies, Montreal, PQ) may be useful for non-invasively monitoring human physiology in a number of applied settings. The Astroskin® biometric shirt measures and records continuous heart rate (HR), blood oxygenation (SPO2), systolic blood pressure (SBP) and respiratory rate (RR). The aim of this study was to establish the reliability and validity of the Astroskin® biometric shirt. This was achieved through comparing the Astroskin® with a commercially available hospital-grade cardiac monitor, the corpuls3® (Stemple GmbH, Kaufering, Germany) for the …

Determining The Barriers To The Use Of Post-Match Fatigue Monitoring In The Rugby Codes: A Concept Mapping Study., Mitch Naughton, Tannath Scott, Dan Weaving, Scott Mclean, Colin Solomon

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 5: Issue 1, Article 3, 2024. The rugby codes (i.e., rugby union, rugby league, rugby sevens [termed ‘rugby’]) are team-sports that impose complex physical demands upon players which in-turn, leads to domain-specific fatigue (e.g., neuromuscular, cardio-autonomic). Quantifying post-match fatigue through various methods and metrics is important to monitor player fatigue status, which influences training readiness. The specific and general barriers limiting the use of post-match fatigue monitoring in rugby are not presently known. Therefore, the aims of this study were to identify specific and general barriers (clusters of specific barriers) to the use …

Facile One-Pot Synthesis And Anti-Microbial Activity Of Novel 1,4-Dihydropyridine Derivatives In Aqueous Micellar Solution Under Microwave Irradiation, Asmita Goswami, Navneet Kaur, Manvinder Kaur, Kishanpal Singh, Harvinder Singh Sohal, Haesook Han, Pradip K. Bhowmik

Chemistry and Biochemistry Faculty Research

The current study describes a novel and eco-conscious method to synthesize 1,4-dihydropyridine derivatives utilizing an aqueous micellar solution containing aluminum dodecyl sulfate, Al(DS)3, using readily available starting material. The final products were synthesized with excellent yields within remarkably quick reaction durations, promoting remarkable atom economy and minimizing environmental impacts. The present protocol has several advantages over other methodologies in terms of high yield (up to 97%) with excellent purity. Further, the synthesized 1,4-DHPs exhibit favorable to excellent resistance against examined bacterial and fungal species. Intriguingly, polar groups on the phenyl ring (5b, 5c, 5i and 5j) make the 1,4-DHPs equally …

Kinematic Characteristics Of Novices’ Sprint Techniques At Maximum Velocity Phase, Saburo Nishimura, Yoshinori Kinomura

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 5: Issue 1, Article 2, 2024. Sprint performance is a crucial aspect of achieving high performance across a range of sports. However, previous studies analyzing the sprint technique of novices have yielded disparate findings regarding effective sprint techniques. For instance, Saito and Ito (1995) found no significant difference in the maximum thigh angle of the free leg between boys aged 7 to 12 and sprinters. Conversely, Katoh et al. (2001) reported that elementary school sprinters indicated a larger maximum thigh angle of the free leg than novice elementary children. Inconsistency like this makes …

The Use Of Fecal Microbiota Transplant In Overcoming And Modulating Resistance To Anti-Pd-1 Therapy In Patients With Skin Cancer, Tahne Vongsavath, Rodd Rohmani, Kyaw Min Tun, Vignan Manne

Department of Internal Medicine Faculty Research

While immune checkpoint inhibitors have evolved into the standard of care for advanced melanoma, 40–50% of melanoma cases progress while on therapies. The relationship between bacterium and carcinogenesis is well founded, such as in H. pylori in gastric cancers, and Fusobacterium in colorectal cancers. This interplay between dysbiosis and carcinogenesis questions whether changes in the microbiome could affect treatment. Thus, FMT may find utility in modifying the efficacy of anti-PD-1. This review aims to examine the use of FMT in treatment-resistant melanoma. A literature search was performed using the keywords “fecal microbiota transplant” and “skin cancer”. Studies were reviewed for …

Acute Ingestion Of Dark Chocolate Fails To Affect Running Economy In Recreational Female Runners, Bianca J. De Lucia, Beau Kjerulf Greer, Christopher B. Taber

Topics in Exercise Science and Kinesiology

Topics in Exercise Science and Kinesiology Volume 5: Issue 1, Article 1, 2024. Ingestion of dark chocolate (DC), a dietary source high in flavanols, may increase nitric oxide bioavailability. Elevating blood nitric oxide concentrations may augment metabolic efficiency by reducing the amount of oxygen or energy needed to perform a given task. Utilizing a crossover design, the purpose of this study was to investigate the effect of acute ingestion of DC on running economy (RE). Nineteen recreationally trained females (age: 20±1 years) volunteered for this investigation, with 16 completing all procedures (n = 16). Two-hours before RE assessment, participants consumed …

The Behemoth Of The Last Ice Age: The Evolutionary Saga Of The Columbian Mammoth In North America, Nathaniel Valentine

Calvert Undergraduate Research Awards

The Columbian’s mammoth evolutionary history can be traced back to the origin of life and its evolutionary lineage can be tracked down by examining select species over geologic time. I conducted a literature review with multiple scientific journals to identify key transitional species that trace their lineage to the Columbian mammoth. Transitional species were selected from the Precambrian and the various periods of the Phanerozoic which exhibited vertebrate-like body structures and behaviors. Evidence suggests that early vertebrate-like animals were present by the Cambrian period. Mammal evolution would continue in the Mesozoic era and radiate in the Cenozoic era. The Columbian …

Variation In Las Vegas Tree Diversity Based On Socioeconomic Status, Fabrizio Ciccone

Calvert Undergraduate Research Awards

An increased level of plant biodiversity has been observed in urban communities of above average socioeconomic status. This phenomenon was previously termed the luxury effect. This study aimed to identify potential disparities in tree diversity of different communities across Las Vegas and Henderson. Communities were selected based on the zip code’s median income for 2023; this information was gathered from the Healthy Southern Nevada database. Public parks were chosen from a range of zip codes, with trees initially being identified with PictureThis, then cross-referenced with Southern Nevada Water Authority’s regional plant list for validity. Trees were counted, identified, and …

Unlv Title Iii Aanapisi & Mcnair Scholars Institute Research Journal 2024, Jesica Godinez-Paredes, Kian Hassankhan, Apia Hickman, Robin Ruth Kee, Kevin Ayala Pineda, Briana Melendez, Kalli Ramos, Saturn L. Reyes, Fabian Leija, Selena Pepe, Silva Topchyan, Celeste Ainsley, Mayra Arzate, Jessica Balistreri, Zantana Ephrem, Mirella Jasso, Karl Panou, Nichole Pelaez, Miklo Alcala, Akshay Dave, Mey Mey Heng, Michael Finkle, Janessa Montenegro, Reynafe Naol Aniga, Victor Mejia, Angelica G. Diaz, Anayeli Flores-Garibay, Kari Lee Joe Goold, Samantha Hernandez, Lianelys Cabrera Martinez, Caitlin Reynolds, Kimberly N. Usbeck, Abdulrahman Alahdal, Angelica Diaz, Willaine Mae Kahano, Raquel Jackson, Cecia Ruiz-Hernandez, Kers Ung-Watson, Yessenia Henriquez, Vanessa Marie Booth, Alexia Brown, Darlyn Magana, Bianca Navarro, Nicholas Pereira, Gia Renemae Calip, Lucky Heng, Ralph Sagun, Lucas Abreu, Alexandra Maria Acosta, Tristan Benally, Cosset Hernandez Pena, Adrian Montenegro, Cierra Paaaina-Daquioag, Nicole Torosian, Tracy Fuentes, Julissa Martinez, Medina Mcallister, Michal Newhouse-Van Vlerin, Tiria Carr, Nima Abkenar, Isabella Aceituno, Yuhan Bi, Victoria Campos, Melika Cummings, Zachary J. Johnigan, Alexis Sotolongo-Marin

McNair Journal

Journal articles based on research conducted by undergraduate students in the AANAPISI, LSAMP, and McNair Scholars Program.

Table of Contents

About AANAPISI

Dr. Chris Heavey, Interim President

Dr. Keith Rogers, Vice President for Student Affairs

Ms. Zhanna Aronov, Associate Vice President for Retention & Outreach

A Timeline Of Klinefelter’S Syndrome, Xxy, Emma Chevalier, Tyler Venegas, Mary Salibi

Undergraduate Research Symposium Posters

Klinefelter Syndrome (KS) is a non-mendelian chromosomal disorder consisting of supernumerary X chromosomes in males, 80% of which manifest as the 47,XXY karyotype. The resulting gene dosage abnormalities affect both cognitive and physical development, with variable expressivity. The disease was first described by Harry Klinefelter in 1942 and was thought to be an endocrine disorder until the late 1950s, when karyotyping of affected individuals revealed an extra X chromosome.

(It is the most common sex chromosome aneuploidy (1:500 males) and the most common cause of azoospermia. The phenotype for KS is highly contested due to its extremely variable expressivity and …

A Genetic Screen For Metabolic Modulators In Drosophila Melanogaster, Victoria Campos, Logan Kazimer, Brandon Polimeni, Katelyn Niswonger, Matthew Meiselman

Undergraduate Research Symposium Posters

When environments become unfavorable, to preserve energy, animals will attenuate reproduction and limit growth. This evolutionary strategy requires perceiving and assessing a complex environment, a long-standing role of the nervous system. However, the nervous system’s control over endocrine states remains a monumental challenge. Here, we propose to exploit the genetic accessibility and cellular resolution readily found in Drosophila melanogaster, to fully explore how the brain controls metabolic and reproductive states. This project relies on the Meiselman Lab’s established unbiased neural activation screen, which located new neural circuits that participate in metabolic control. The project proposes the use of the split …