Life Sciences Commons^™

Biomechanical Comparison Of A Rounded Outsole Shoe And Traditional Outsole Shoe, Sarah Horsch

UNLV Theses, Dissertations, Professional Papers, and Capstones

The purpose of the study was to determine the effects of shoe outsole design on maximum vertical acceleration and select kinematic parameters during level and uphill walking across phases of stance. Twelve participants, 7 males (75.1±9.3 kg, 173.6±3.6 cm, 22.9±3.5 yrs) and 5 females (56.5±5.1 kg, 158.3±4.5 cm, 25.4±11.1 yrs) granted written consent and preferred walking speed was determined. An accelerometer (480 Hz) was attached to the distal leg to measure maximum leg acceleration (Aleg) and an electrogoniometer (480 Hz) was placed on the back to measure sagittal lumbar motion (LumbarROM). Sagittal video capture (60 Hz) included thigh range of …

Effects Of Environmental Variables On The Reproduction Of Quagga Mussels (Dreissena Rostriformis Bugensis) In Lake Mead, Nv/Az, Richard Steven Ianniello

UNLV Theses, Dissertations, Professional Papers, and Capstones

In 2007, quagga mussels (Dreissena rostriformis bugensis) were found in Lake Mead and have spread downstream on the Colorado River and to other lakes and reservoirs in the Southwestern United States. The quagga mussel's extremely quick colonization of Lake Mead and annual veliger abundance trends provide evidence that the quagga mussels in the Southwest have different reproductive behavior than in previous habitats. This study is one of the first to specifically examine quagga mussel reproduction in the Southwest and examines how quagga mussel reproduction varies at sites known to have different temperatures and other environmental variables resulting from the input …

Understanding Effects Of Changes In Land Use, Environmental Parameters, Habitat Characteristics On The Great Basin Aquatic Invertebrates Using Ecological Stoichiometric Theory, Knut Mehler

UNLV Theses, Dissertations, Professional Papers, and Capstones

Many freshwater ecosystems in the Great Basin have undergone dramatic alteration over the past decades due to groundwater withdrawal, water diversion and changes in land use. These changes have affected benthic food web dynamics by altering the availability of chemical key elements for primary and secondary producers, by loss of biodiversity and extinction of endemic species. However, only few studies are available that addresses the link between changes in land use, habitat characteristics and its effects on benthic macroinvertebrates (BMI) communities comprehensively and little attention has been given to integrating physiochemical aspects to link ecosystem functions.

This dissertation analyzes the …

Examination Of Lower Extremity Muscle Activity During An Overhand Lacrosse Shot In Females, Brianna Millard

UNLV Theses, Dissertations, Professional Papers, and Capstones

This study intends to provide a basic biomechanical understanding of a specific movement within the sport of lacrosse, an overhand goal shot. Its purpose is to identify the different muscles of the lower extremity and the roles they perform during each phase of the lacrosse shot. Specifically, the study will compare how active muscles are between phases as well as between two different shot speeds. This research provides insight into the importance of timing muscle contractions that lead to a more accurate and faster shot.

Subjects (n=5 females, age: 21.8 ± 2 years, height: 162.56 ± 15.24cm, mass: 63.68 ± …

Predicting Chest Press Strength From A 4rm Triceps Brachii Exercise In Trained Women, Krystina Nadia Moschella

UNLV Theses, Dissertations, Professional Papers, and Capstones

Determining maximal strength is important when developing a resistance exercise program for trained athletes. The most frequent strength procedure used to evaluate maximum strength is the 1RM test. However, risk of injury from a 1RM test increases for the athletes, therefore a 4RM test is used in the following study. The purpose of the study is to test whether there is a linear relationship between the bench press and the triceps rope extension exercise. A secondary purpose is the development of a prediction equation for the purpose of prescribing bench press exercise loads from triceps brachii loads using a 4RM …

Additive Effects Of An External Focus And Enhanced Expectancy In Learning A Motor Skill, Luigi Antonio Pascua

UNLV Theses, Dissertations, Professional Papers, and Capstones

An external focus of attention in has been shown to produce better performance in practice and retention of a motor skill when compared to an internal focus or control conditions in which no attentional focus cues are given to the learner (for a review, see Wulf, 2012). Enhancing learner expectancy (e.g., via positive feedback) has also been shown to improve learning (e.g., Lewthwaite & Wulf, 2010). This study sought to investigate whether combining the positive effects of an external focus of attention with an enhanced learner expectancy (through positive social-comparative feedback) would enhance learning relative to either variable alone or …

The Effects Of Starvation Selection On Drosophila Melanogaster Life History And Development, Lauren A. Reynolds

UNLV Theses, Dissertations, Professional Papers, and Capstones

In nature, animals may endure periods of famine to complete their life cycles. Starvation stress will increase in populations as climates around the world change. To predict how populations may respond to such a stress, laboratory experimentation becomes essential. The evolutionary process of adaptation, its innovations and their trade-offs, can be studied in populations experiencing starvation stress. For this purpose outbred populations ofDrosophila melanogasterwere selected for starvation resistance in the laboratory.

After 60+ generations of starvation selection the starvation-selected flies have gone from surviving 2-3 days without food to 12-14 days without food. How this amazing feat of resistance is …

Firefighter Fitness-For-Duty Medical Screening: A Peer Review Quality Improvement Pilot, Julie Collings Rochefort

UNLV Theses, Dissertations, Professional Papers, and Capstones

Despite the overwhelming evidence that sudden cardiac death is the most frequent cause of firefighter fatalities, many fire departments do not have a program to measure or maintain basic firefighter fitness and health. This project evaluated and compared medical screening outcomes of four industrial fire brigades within a multinational oil and gas corporation and introduced a quality improvement plan. The goal of this project was to apply the evidence and measure outcomes to determine the most effective way to ensure that firefighters in a corporate setting are healthy. This was accomplished by utilizing established guidelines in developing an educational program …

The Effects Of Chronic Calcium Dysregulation On Behavioral And Pathological Features Of Alzheimer's Disease, Jonathan Sabbagh

UNLV Theses, Dissertations, Professional Papers, and Capstones

Alzheimer's disease (AD) is a progressive neurodegenerative disorder whose etiology is unknown. Recent studies have implicated alterations in calcium homeostasis as a pathogenic contributor to AD. Calcium dysregulation has been observed in aged and AD brains, an event which could potentially facilitate the development of multiple pathologies observed in AD. Specifically, disrupting intracellular calcium levels in vitro has been demonstrated to increase amyloid-beta (Aβ) production, tau phosphorylation, and neuronal loss. However, there is a paucity of data on the behavioral and biochemical consequences of chronic in vivo perturbation of calcium homeostasis. In a series of experiments designed to evaluate the …

Development And Implementation Of A Video-Based Activity Preference Assessment For Children With Autism And Their Parents, Lena Sankovich

UNLV Theses, Dissertations, Professional Papers, and Capstones

Development and Implementation of a Video-Based Physical Activity Preference Assessment for Children with Autism and Their Parents

Individuals with autism often lack the necessary motivation to engage in physical activity. In addition, due to the characteristics defining autism, such as deficits in social skills, motor coordination, and behavior, individuals with autism are less likely to participate in physical activity with their peers than individuals without autism. Additionally, poor motor functioning, sedentary lifestyle, lack of information and lack of access to physical activity may be barriers to physical activity for individuals with developmental disabilities. These barriers, in addition to the characteristics …

Soil Moisture Recognition And The Spatial Distribution Of Storm Activity In The Mojave Desert Using High-Resolution Aster And Modis Imagery For Thermophysical Mapping, Russell J. Skuse

UNLV Theses, Dissertations, Professional Papers, and Capstones

Climate models suggest that the Mojave Desert ecoregion is vulnerable to becoming drier in the future, and as the human population grows and development increases, environmental stresses will likely increase. Determining the spatial distribution and variation of soil moisture on a regional scale is an essential component to climate change, hydrologic, and habitat analyses. Soil permeability and sediment stability are characteristics that have been shown to be measurable from remote sensing observations. The primary objective of this project is to map the mechanical composition of the surface materials in the Mojave Desert ecoregion with implications for soil permeability, sediment stability, …

Examining Lower Extremity Range Of Motion And Movement Variability Chages Due To Focus Of Attention During Landing, Andrew Nordin, Janet Dufek

Interdisciplinary Research Scholarship Day

Attentional focus (AF) has been explored among a variety of motor skills providing evidence that external AF promotes automaticity and enhanced performance [6]. External focus of attention is distinguished from internal focus such that external focus is directed toward movement effect rather than body movements [6]. Movement variability provides a means of assessing functional characteristics of the neuromotor system, where normal functioning is suggested to occur within optimal limits, while excessively high or low movement variability is indicative of system dysfunction [2,4,5]. Additionally, the ability of the motor system to vary, or broadly distribute, internal loads is thought to reduce …

Kinematic Effects Of Stride Length Perturbations On System Com Horizontal Velocity During Locomotion, Josh Bailey, Andrew Nordin, Janet Dufek, D. Lee

Interdisciplinary Research Scholarship Day

PURPOSE: To investigate the kinematic effect on the systems’ center of mass horizontal velocity in response to stride length perturbations. METHODS: Twelve healthy adults (23.1±7.71 yrs; 1.69±0.1 m; 66.82±12.6 kg; leg length 894.7±66.1 mm) performed 5 trials of preferred speed walking (PW) and running (PR)followed by 5 stride length perturbations based on percentages of leg length (60%, 80%, 100%, 120% and 140%). 3D kinematic analysis was completed using a 12-camera infrared motion capture system (Vicon, 200hz). Dependent variables computer for each condition included: center of mass horizontal velocity at the highest vertical position (COMHVhi) and at the lowest vertical position …

Step Length Perturbations Alter Variations In Center Of Mass Horizontal Velocity, Josh Bailey, Andrew Nordin, D. Lee, Janet Dufek

Interdisciplinary Research Scholarship Day

PURPOSE: The purpose of the study was to investigate the effects of SL perturbations on system COM forward velocity (vx) during walking gait. METHODS: Eight healthy adults (23.5±3.6 yrs; 1.72±0.18 m; 73.11±15.29 kg) performed 5 trials of preferred speed walking (PW) and running (PR) followed by 5 stride length perturbations based on percentages of leg length (LL: 60%, 80%, 100%, 120% and 140%). 3D kinematic analysis was completed using a 12-camera infrared motion capture system (Vicon MX T40-S, 200Hz). Data filtering and interpolation included a low pass, 4th order Butterworth filter (cutoff frequency 15Hz) and cubic (3rd order spline). Maximum …

Immediate Effects Of Neurodynamic Versus Muscle Stretching On Hamstring Flexibility In Subjects With Short Hamstring Syndrome, Yolanda Castellote-Caballero, Marie C. Valenza, Louie Puentedura, Cesar Fernandez-De-Las-Penas, Francisco Albuquerque-Sendin

Interdisciplinary Research Scholarship Day

To compare the effectiveness of an isolated neurodynamic sciatic sliding technique (Neurodynamic group) versus static stretching (Stretching group) in comparison to a Control group receiving a placebo intervention.

Effects Of Footstrike On Low Back Posture, Shock Attenuation, And Comfort In Running, Traci L. Delgado, Emilia Kubera-Shelton, Robert R. Robb, Robbin Hickman, Harvey Wallmann, Janet Dufek

Interdisciplinary Research Scholarship Day

To determine if a change from rearfoot strike (RFS) to forefoot strike (FFS) would change lumbar lordosis, influence shock attenuation, or change comfort levels in healthy recreational/experienced runners.

Effects Of Shoe Outsole Design And Incline On Walking Biomechanics, Sarah Horsch, Janet Dufek

Interdisciplinary Research Scholarship Day

The purpose of the study was to examine the effects of incline at foot contact of treadmill walking between rounded outsole (ROS) and traditional outsole (TOS) shoes. A rounded outsole shoe (ROS) is specifically designed with a fulcrum under the sole so that when the mass of the body is over it, the foot is forced to roll anteriorly. Traditional ROS studies have included analyses on bipedal stance single leg standing, muscle
activity during treadmill walking, kinetics during over ground walking, and kinematics after a 6-week accommodation period. Presently, there is no research comparing a ROS and a TOS at …

Physically Interactive Games Increase Vo2 Above Resting Metabolic Rate, Shaelee Allen, Jacob E. Barkley, Janet Dufek, Paul Hafen, Michael Jarrett, Krystina Moschella, James Navalta, Robert Rietjens, Richard Tandy, Antonio Santo

Interdisciplinary Research Scholarship Day

The purpose of this study was to determine the energy cost, beyond resting metabolic rate (RMR), of playing select games on the Nintendo Wii for 30 contiguous minutes. Physically interactive games (i.e. Basic Run and Basic Step) increase energy expenditure above resting values compared to a sedentary game (Tanks!) and therefore may help individual’s become more active. Furthermore, Basic Run and Basic Step elicited MET values of 3.9 and 3.2, respectively, which is considered moderate-intensity exercise and could be used to meet daily recommendations for physical activity.

Interactive Video Gaming Maintains Vo2 & Hr At Current Recommended Exercise Intensities For Cardiovascular Fitness, Michael Jarrett, Shaelee Allen, Jacob E. Barkley, Janet Dufek, Paul Hafen, Krystina Moschella, James Navalta, Robert Rietjens, Richard Tandy, Antonio Santo

Interdisciplinary Research Scholarship Day

The purpose of this study was to determine the energy cost of playing select games on the Nintendo Wii for 30 contiguous minutes and whether or not the physical interaction of the participant with the gaming system and subsequent physiologic intensity diminishes with playing time.

Gender Differences In Frontal Plane Lower Extremity Kinetic Variability During Landing, Andrew Nordin

Interdisciplinary Research Scholarship Day

Investigations of human movement variability have been used as a
means of exploring neuromotor functioning, where performance variability is
thought to provide the system with flexibility and a mechanism for adaptation to
movement repetition [1,2,4,6]. Operationally, variability has been considered to
fall within optimal limits (Figure 1), while excessively high or low variability has
been implicated in injury susceptibility [1,2,4,6]. Landing has been explored
due to a high incidence of injury in athletic performance, as well as the ability
to easily control task demands through increases in landing height [3,4].
The purpose of this investigation was to evaluate changes in …

Enrollment In Yfv Vaccine Trial: An Evaluation Of Recruitment Outcomes Associated With A Randomized Controlled Double-Blind Trial Of A Live Attenuated Yellow Fever Vaccine, Paula M. Frew, Eve T. Shapiro, Lu Lu, Srilatha Edupuganti, Harry L. Keyserling, Mark J. Mulligan

Environmental & Global Health Faculty Research

This investigation evaluated several factors associated with diverse participant enrollment of a clinical trial assessing safety, immunogenicity, and comparative viremia associated with administration of 17-D live, attenuated yellow fever vaccine given alone or in combination with human immune globulin. We obtained baseline participant information (e.g., sociodemographic, medical) and followed recruitment outcomes from 2005 to 2007. Of 355 potential Yellow Fever vaccine study participants, 231 cases were analyzed. Strong interest in study participation was observed among racial and ethnically diverse persons with 36.34% eligible following initial study screening, resulting in 18.75% enrollment. The percentage of white participants increased from 63.66% (prescreened …

Accessible Medical Equipment For Patients With Disabilities In Primary Care Clinics: Why Is It Lacking?, Jennifer Renee Pharr

Environmental & Global Health Faculty Research

Background: Previous research has identified inaccessible medical equipment as a barrier to health care services encountered by people with disabilities. However, no research has been conducted to understand why medical practices lack accessible equipment.

Objectives/Hypothesis: The purpose of this study was to examine practice administrators’ knowledge of accessible medical equipment and cost of accessible medical equipment to understand why medical practices lack such equipment. Hypotheses were: 1) Practice administrators lacked knowledge about accessible medical equipment and 2) The cost of accessible medical equipment was too great compared to standard equipment for the clinic.

Methods: This study was a mixed methods …

Magnetotactic Bacteria From Extreme Environments, Dennis A. Bazylinski, Christopher T. Lefèvre

Life Sciences Faculty Research

Magnetotactic bacteria (MTB) represent a diverse collection of motile prokaryotes that biomineralize intracellular, membrane-bounded, tens-of-nanometer-sized crystals of a magnetic mineral called magnetosomes. Magnetosome minerals consist of either magnetite (Fe₃O₄) or greigite (Fe₃S₄) and cause cells to align along the Earth’s geomagnetic field lines as they swim, a trait called magnetotaxis. MTB are known to mainly inhabit the oxic–anoxic interface (OAI) in water columns or sediments of aquatic habitats and it is currently thought that magnetosomes function as a means of making chemotaxis more efficient in locating and maintaining an optimal position for …

Walking Box Ranch Planning And Design Quarterly Progress Report: Period Ending January 10, 2013, Margaret N. Rees

Walking Box Ranch

• BLM notified UNLV on Nov 7, 2012 that they had cancelled the WBR solicitation for a general contractor and that they were reconsidering the scope of the project. BLM and UNLV met on Nov. 22, 2012 and BLM updated UNLV on their decision to terminate the task agreement for the field and research station, and to modify plans for interpretation at the future WBR Visitor Center. BLM and UNLV will meet Feb. 7, 2013 to discuss the path forward regarding interpretation and the Visitor’s Center.
• UNLV is continuing to work with direction from Carolyn Shelton, BLM interpreter, to collect interpretive …

Ketamine Induced Deficits In Working Memory With Relevance To Schizophrenia, Michael A. Langhardt, Jefferson Kinney

McNair Poster Presentations

Schizophrenia is a chronic debilitating brain disorder, which affects approximately one per­cent of the adult population worldwide. The symptoms of schizophrenia are commonly divided into three broad classes: positive symptoms, negative symptoms, and cognitive disturbances (Kay, et al., 1987). The positive symptoms of schizophrenia include hallucinations, delusions, and dis­organized thinking, while the negative symptoms include affective flattening, social withdrawal, and an inability to plan and carry out future activities. The cognitive disturbances exhibited in schizophrenia include deficits in spatial reference and working memory as well as difficulties with focus and attention (Lewis et. al., 2007). Several models have been proposed …

Biogeography And Phylogeny Of Aigarchaeota, A Novel Phylum Of Archaea, Gisele Braga Goertz, Brian P. Hedlund

McNair Poster Presentations

‘Aigarchaeota’ is a candidate phylum of Archaea known only by 16S rRNA gene fragments from cultiva­tion-independent microbial surveys and a single composite genome from Candidatus ‘Caldiarchaeum sub­terraneum’, an inhabitant of a subterranean gold mine in Japan. Gene sequences associated with ‘Aigarchaeo­ta’ have been found in a variety of geothermal habits, however a comprehensive analysis of the phylogeny and distribution of ‘Aigarchaeota’ has not yet been done. Public databases were mined for 16S rRNA gene sequences related to known ‘Aigarchaeota’ and a combination of approaches were used to rigorously define the phylogenetic boundaries of the phylum, investigate its distribution, and …

Are Incomplete Denitrification Pathways A Common Trait In Thermus Species From Geothermal Springs In China?, Julienne J. Paraiso, Brian P. Hedlund

McNair Poster Presentations

Temperature has strong impacts on ecosystem function and biogeochemical cycles, particularly within extreme environments such as geothermal springs above 60 °C. The primary focus of this study was to investigate the denitrification pathways of Thermus (Bacteria) isolates from geothermal springs from Tengchong, China. This study tested the hypothesis that incomplete denitrification is a common characteristic of the genus Thermus, regardless of geographic origin or species affiliation, which would implicate them in the efflux of nitrous oxide (a strong greenhouse gas) to the atmosphere. In this study, we cultivated 25 isolates, including six known Thermus species, and measured the stoichiometry …

An Acute Inflammatory Response In A Diabetic Alzheimer’S Disease Model, Krystal Courtney D. Belmonte, Jefferson Kinney

McNair Poster Presentations

Alzheimer’s disease (AD) is the most common form of dementia, accounting for 50 to 80 percent of all dementia cases. This neurodegenerative disease leads to neuronal death and tissue loss in the brain, resulting in the slow deterioration of memory, thinking skills, and eventually even the ability perform daily tasks. While it is not a normal part of aging, AD is mostly diagnosed in people over the age of 65; thus, the main risk factor for Alzheimer’s disease is increased age, though it is most likely other additional factors also contribute (Heese & Akatsu, 2006). Neuropathological hallmarks of AD include …

Evolution Of The Human Diet: What We Can Learn From Hunters And Gatherers, Kara Osborne, Alyssa Crittenden

McNair Poster Presentations

The study of hunter-gatherer populations around the world can greatly inform our understanding of the evolution of the human diet. Ethnographic research of modern hunter-gatherers has been used to infer the possible food consump­tion and acquisition patterns of our ancestors. Hunter-gatherers provide the in­formation necessary for the understanding of the past human diet, due to these populations living similar lifestyles in similar environments, therefore procuring similar foods.

The Hadza, a group of nomadic hunters and gatherers living in Tanzania, East Africa, are one of the primary populations that nutritional anthropologists study to infer what possible foods our ancestors acquired and …

Predicting Barriers To Primary Care For Patients With Disabilities: A Mixed Methods Study Of Practice Administrators, Jennifer Renee Pharr, Michelle Chino

Environmental & Global Health Faculty Research

Background. People with disabilities continue to be identified as a group who experience disparate health/health care. They are less likely to engage in some health care services. Structural barriers are often identified as one of the reasons for the underutilization of some health care services by people with disabilities. However, to date no study has been conducted to understand why structural barriers persist twenty years after the Americans with Disabilities Act (ADA) became law.

Objectives. We examined the relationship between primary care practice administrators’ knowledge of the ADA and the number of accessibility barriers that patients with mobility disabilities might …