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Henry Ford Hospital Medical Journal

1989

Articles 61 - 64 of 64

Full-Text Articles in Life Sciences

Hormonal Management Of Advanced Adenocarcinoma Of The Prostate, Brian J. Miles Mar 1989

Hormonal Management Of Advanced Adenocarcinoma Of The Prostate, Brian J. Miles

Henry Ford Hospital Medical Journal

No abstract provided.


Quinidine-Induced Immune Thrombocytopenia, Mansoor N. Saleh, Nadhav Dhodaphar, Karen Allen, Albert F. Lobuglio Mar 1989

Quinidine-Induced Immune Thrombocytopenia, Mansoor N. Saleh, Nadhav Dhodaphar, Karen Allen, Albert F. Lobuglio

Henry Ford Hospital Medical Journal

We have identified six cases of quinidine-induced immune thrombocytopenia based on clinical evidence and in association with elevated amounts of platelet surface IgG. The degree of thrombocytopenia did not correlate with severity of clinical symptoms, nor did it predict the amount of IgG on the platelet surface. Three of the patients recovered promptly after drug discontinuation alone whereas the other patients received additional corticosteroid therapy. The clinical presentation, mode of diagnosis, and therapeutic considerations in the treatment of drug-induced thrombocytopenia are discussed.


Primary Fibrinolysis In Acute Monocytic Leukemia, Ellis J. Van Slyck, Sundara B. K. Raman, Nalini Janakiraman Mar 1989

Primary Fibrinolysis In Acute Monocytic Leukemia, Ellis J. Van Slyck, Sundara B. K. Raman, Nalini Janakiraman

Henry Ford Hospital Medical Journal

We present the case of a young man with acute monocytic leukemia (French-American-British classification:M5) and systemic hyperfibrinolysis with severe bleeding. Although fibrinolysis is usually mild and secorulary to disseminated intravascular coagulation, its role as a primary and dominant factor in rare cases of leukemia warrants that its presence be sought as a cause of abnormal bleeding. Decreased serum plasminogen and increased serum plasmin determined by synthetic substrate assay and a negative protamine paracoagulation test are crucial findings. Use of high-dose epsilon-aminocaproic acid was effective in treating this complication. A transient increase in fibrinolytic activity coincident with the early effect of …


Cerebral Infarction Associated With Cocaine Use, Iliana Meza, Carlos A. Estrada, Justo A. Montalvo, Walter N. Hidalgo, Jennie Andresen Mar 1989

Cerebral Infarction Associated With Cocaine Use, Iliana Meza, Carlos A. Estrada, Justo A. Montalvo, Walter N. Hidalgo, Jennie Andresen

Henry Ford Hospital Medical Journal

We report the case of a young man with an acute infarction of the left putamen and caudate nucleus, whose symptoms appeared six hours after intranasal use of approximately 0.5 g of cocaine hydrochloride. It seems probable that in this patient cocaine consumption played a role in the development of stroke.