Life Sciences Commons^™

Interactions Between Red Foxes And Coyotes Across Urban And Wild Habitats, Caroline E. Savage, Taylor S. Readyhough, Remington J. Moll, Jonathon D. Cepek

UNH URC Open (2026 and after)

Dens are critical to the life history of many mammal species, particularly when raising young. Excavating a den is energetically costly, so several species can use existing dens, and multiple species may inhabit the same den complex simultaneously. However, the extent of den sharing among urban mammals is understudied. Between March 2021, and June 2023, we used camera traps to monitor a multi-species den site in Cleveland, Ohio, USA. We documented den visitation and use by at least 11 mammal species, including red fox, coyote, raccoon, woodchuck, and Virginia opossum. Coyotes and red foxes both exhibited scent-marking at the den …

New Hampshire Shellfish Under Pressure: Physiological Effects Of Climate Change And Toxic Algal Blooms, Olivia Boyan

UNH URC Open (2026 and after)

Climate change driven effects on the ocean, including warming water, acidification, and changes in the presence of harmful algal blooms (HABs) are causing metabolic pressures on marine organisms, particularly in the Gulf of Maine. Shellfish are susceptible to these pressures because their metabolic processes including growth and respiration are influenced by water temperature, pH, and consumption of algal toxins. This study investigates the effects of ocean warming, acidification, and diet toxicity level on the growth and respiration of Blue mussels (Mytilus edulis), Eastern oysters (Crassostrea virginica), and Sea scallops (Placopecten magellanicus). Selected individuals were subjected to water treatments simulating ambient …

Presence Of Road Salts In Vernal Pools And Effects On Amphibian Development, Grace I. Bemis, Ella Mack

UNH URC Open (2026 and after)

Presence of Road Salts in Vernal Pools and Effects on Amphibian Development

Automation And Habitat Development For A Space Based Marine Life Environment, Logan Trimmer, Alexander Hang

Harrisburg University Other Works

This project was a cross-collaboration between the Environmental Sciences and Advanced Manufacturing and Robotics programs for the company Monolith Space.

The goal of this project was to design an autonomous system to be able to track qualities of water in an aquaculture system designed to be sent to space.

Modeling Mineral Redistribution In Biological Tissue Using Apple As An In Vitro Analogue, Daler Djuraev, Ali Algemsh, Halima Alazeb, Zeenia Ahmed

Publications and Research

This project aims to model mineral (ion) redistribution that occurs in human soft tissue after injury or mechanical/thermal stress. Because direct, repeatable in vivo measurements are difficult, we use apples as an in vitro analogue: their mineral content is relatively uniform and the tissue can be cut, dried, and repeatedly imaged under controlled conditions. Using X-ray imaging, we tracked how minerals in apple tissue move toward damaged regions immediately after cutting, and how subsequent drying at room temperature drives a redistribution toward the central core. We also observed that biological degradation (decay) alters mineral density over time, indicating that even …

Patent Searching With Uspto, Derwent Innovation And Lens.Org, Ibis Anette Moreno-Lozano

Day Family Research Lab Workshop Series

No abstract provided.

Designing And Writing Effective Data Management Plans For Grant Proposals, Rubab Shahzad, Ibis Anette Moreno-Lozano

Day Family Research Lab Workshop Series

Fundamentals of research data management and how to create effective Data Management Plans (DMPs).

Data Cleaning With Excel, Rubab Shahzad

Day Family Research Lab Workshop Series

This workshop will delve into the importance of cleaning research data and why clean data is an important part of the larger research data lifecycle. This session will also provide an overview of data cleaning and preprocessing using Microsoft Excel including a hands-on demonstration.

Scroll down for practice file

Deforestation Affecting Developing Nations, Nicole Villa

Sustainability Conference

Deforestation continues to be a growing problem around the globe, while it is affecting wildlife what can be overlooked is the challenges it’s creating for the livelihood of nations. This goes beyond losing the biodiversity of our ecosystems but social consequences with the scarcity of water in Malawi, rise in health risks in Democratic Republic of Congo and negative effects of agricultural expansion in Belize. Overall social conflict in these areas that are suffering to grow. Furthermore, I aim to cover the major challenges previously mentioned followed by counteracts of deforestation including action plan in Brazil, efforts of other countries …

Tableau Part Ii - October 2025, Rubab Shahzad

Day Family Research Lab Workshop Series

Part Two of Introduction to Tableau. Learn to make cool visualizations using Tableau. A hands-on opportunity where we will go over calculated fields, hierarchies, unions, dashboards, and stories.

Prior experience with Tableau is recommended

Precise Nutrition 2: Regression Equations Using Koh Protein Solubility To Estimate Digestible Lysine And Digestible Arginine In Commercial Lots Of Soybean Meal That Have Undergone Overprocessing Or Auto Combustion, Nelson Ruiz, Carl M. Parsons, Benjamin Parsons

Poultry Science Faculty Publications and Presentations

The objective of this study was to develop regression equations for lysine (Lys) and arginine (Arg) that would allow poultry nutritionists and formulators to estimate amino acid (AA) digestibility in commercial lots of solvent-extracted soybean meal (SBM) using a newly standardized protocol for KOH protein solubility (KOHPS). A total of 82 SBM samples, selected from 100 samples that were analyzed for in vivo AA digestibility, were analyzed for KOHPS. The KOHPS values ranged from 14 to 88 %, while digestible Lys coefficients ranged from 0.47 to 0.96. Digestible Arg coefficients ranged from 0.62 to 0.98. It became evident from total …

Mesoderm-Specific Transcript Has A Role In The Systemic Regulation Of Obesity, Maria J. Orellana Rosales

Thinking Matters Symposium

Mesoderm specific transcript (Mest) expression in white adipose tissue (WAT) is variable in genetically identical mice. Previous studies have shown a connection between Mest high expression and propensity for fat mass expansion. WAT and liver crosstalk has been well documented with hormone-like peptides signaling and regulating important metabolic pathways. The aim of this study is to investigate the correlation between these circulating factors and Mest expression in mice after exposure to a high fat diet (HFD). A group of 120 C57B6/J mice, males and females, were exposed to a HFD (Western Diet, 40 kcal% fat) for 4 weeks (8-12 weeks …

The Effect Of Anthropogenic Sound On Foraging Behavior In Bluegill Sunfish (Lepomis Macrochirus), Dayna Wiley

Celebrating Scholarship and Creativity Day (2018-)

Anthropogenic noise can have adverse effects on fish populations. High-amplitude noise can cause hearing damage and interfere with essential behaviors, including feeding, migration, and reproduction. Studies suggest that fish regularly exposed to boat noise in lakes exhibit different behavioral responses compared to populations in quieter environments. Bluegill sunfish (Lepomis macrochirus) were collected via angling from a “Quiet Lake” (Lake Sagatagan, Collegeville, MN) with no motor use, and a “Loud Lake” (Upper Spunk Lake, Avon, MN) with frequent motor use. Bluegill foraging behavior was examined in response to daily playback of motorboat traffic. Bluegill (n = 5 individuals per trial; n …

Innovation Scholars Program, Lauren Voll, Olivia Latour, Owen Montreuil, Kaennae Mortimer

Celebrating Scholarship and Creativity Day (2018-)

The innovations scholar program spans roughly five months and included two trips to Mayo Clinic Rochester. The team of four undergraduate students and an MBA student worked with Mayo Clinic ventures to assess the viability of a few patents. The project included a 40-page comprehensive paper as well as a 30-minute presentation. The specific details are protected under an NDA agreement however our key takeaways are shared on the poster.

3d Printing Protein-Rrna Mutations In The Ribosome, Abigail Wilson

Senior Honors Projects

Sometimes conveying research can be difficult through two-dimension models. In my project, I aimed to highlight the significance of three-dimensional visualization in science, thereby enhancing the understanding of complex biomedical concepts. Through my work in Dr. Steven Gregory’s lab, I have been studying the ribosome – the macromolecular machine that utilizes messenger RNA and transfer RNA to link together amino acids thereby synthesizing proteins. Proteins are critical for most processes that occur within every cell. I specifically focus on the interactions between ribosomal proteins and ribosomal RNA (rRNA) at the peptidyl transferase center – the active site where amino acids …

Life In Plastic? Not So Fantastic: Marine Plastic Pollution On San Salvador Island, Dayna Wiley

Celebrating Scholarship and Creativity Day (2018-)

Marine plastic pollution, also known as marine macroplastic debris (MMD), impacts many aspects of marine ecosystems. MMD is defined as macroplastic (> 5mm) objects that are deposited in the ocean and are found floating in the water column or washed up on beaches. MMD washup is significantly affected by ocean and wind currents. The Antilles Oceanic Current and the Trade Winds move west across the Atlantic Ocean, and thus were predicted to cause more MMD deposition on the eastern side of San Salvador Island, Bahamas. Beaches on the North (Graham’s Harbor), South (French Bay), East (East Beach), and West (Columbus …

Exercise Physiological Insights Into Exercise-Induced Muscle Cramping: Blood Lactate And Creatine Kinase As Biomarkers In College Students, William Yu

Celebrating Scholarship and Creativity Day (2018-)

Creatine kinase (CK) is an enzyme that's found in the skeletal muscle, heart muscle and brain. When any of these tissues are damaged, they leak creatine kinase into your bloodstream. Elevated CK levels may indicate muscle injuries, cramping, or disease1. There are different types of CK, which are also known as isozymes for the cytoplasm, CK-MM, CK-MB, and CK-BB. CK-MM focuses on musculoskeletal, CK-MB focuses on heart muscles, and CK-BB focuses on the brain tissue. There are also two isozymes in the mitochondria15. Cramping is common problem amongst runners and can be described as “painful, spasmodic contraction of the skeletal …

Ecological Consequences Of Variable Glacial Melting On Arctic Biodiversity: Trophic Shifts And Community Dynamics, Aislyn Malone, Audrey Swart

Celebrating Scholarship and Creativity Day (2018-)

Our project investigated the profound impacts of increasing glacial melting on various trophic levels, habitats, and other ecological processes.

Structure Disorder And Magnetic Behavior Of An Olivine-Type Cathode Material, Hamida Hassan, Madalynn Marshall

Symposium of Student Scholars

Our research investigates the structure disorder and magnetic behavior of Li(Mn,Fe)PO₄, an olivine-type material relevant for lithium-ion battery applications. Using single-crystal neutron diffraction at Oak Ridge National Laboratory, we precisely determined Mn and Fe occupancy, revealing a 56% Fe and 44% Mn distribution at the atomic 4c site within the Pnma space group. Additionally, we observed significant lithium site vacancies (78% occupied), influencing the material's electrochemical and magnetic properties. The varying Mn/Fe ratio affected spin reorientation transitions, shifting from antiferromagnetic alignment along the a-axis to the b-axis. Our findings provide crucial insights for optimizing olivine-based cathodes, enhancing energy …

Distribution Of Mussels In Two Intermittent Upland Streams Of The Arkansas Valley Ecoregion, Aaron A. Brady, Seth Drake, Zach Crain, Kendall Moles

ATU Scholars Symposium

Freshwater mussels are facing an increasing need for conservation due to their declining populations. More data is needed on mussel distributions, especially in tributaries of large rivers to properly conserve and restore populations. Big Shoal Creek and Little Shoal Creek are two upland-tributaries of the Arkansas River (Lake Dardanelle) in which no records exist for freshwater mussel populations. We addressed this knowledge gap by sampling a total of 9 sites in Little Shoal Creek and 18 sites in Big Shoal Creek to determine the abundance and distribution of mussels in these streams. Mussels were sampled using a timed search approach. …

Expression, Characterization, And Comparative Analysis Of Bacillus Bacteriophage Endolysins, Stephen D. Zdgiebloski

Research and Creativity Symposium

Bacteriophages present a promising alternative for combating antibiotic-resistant bacteria without disrupting the normal microbiome or harming human cells. The antibacterial properties of lytic bacteriophages are largely attributed to endolysins, enzymes active in the lytic cycle. Endolysins recognize bacterial cell walls and cleave the peptidoglycan matrix, leading to cell wall disruption. Their specificity and effectiveness against bacterial hosts are determined by two functional domains, including the cell wall binding domain. Our research focuses on characterizing Bacillus phage endolysins. We analyzed the protein sequences of endolysins from six Bacillus phages isolated at the University of Mary Washington. Although these phages were isolated …

Effects Of Pfos On Zebrafish Dopaminergic Neurodevelopment, Allison G. Fletcher

Research and Creativity Symposium

Per- and polyfluoroalkyl substances (PFAS) are a group of environmental contaminants that cause disruptions to the nervous and endocrine systems. Perfluorooctanesulfonate (PFOS) is considered one of the most disruptive PFAS to the nervous system, and may disrupt neurodevelopment of the dopaminergic system, which has been linked to neurodevelopmental disorders like Attention Deficit/Hyperactivity Disorder (ADHD) in humans. I hypothesized that early life PFOS exposure disrupts the development of the dopaminergic system. To test this hypothesis, I exposed zebrafish to 0.05, 0.5, and 5.0 mg/L PFOS through 5 days of embryonic and larval development. To assess acute effects of PFOS on the …

Food & Drugs Unite: Targeting Leukemia With A [6]-Gingerol And 5-Fluorouracil Combination Chemotherapy, Alexa Mazzeo, Samantha Wechsler

Biology Presentations

Leukemia is a cancer found in the blood characterized by rapid growth of blood cells. This study examines the effect of [6]-Gingerol and 5- Fluorouracil (5-FU) on the proliferation of the Jurkat cell line, a cell line that is a model for T-cell leukemia due to similar mechanisms. MTT assay technique was used to measure cell proliferation and viability. We expected to see high cell fractional affect and reduced proliferation as the concentrations of the combinational therapy of [6]-Gingerol and 5-FU increased. These two cell compounds were selected because of their anti-carcinogenic effects: [6]-Gingerol is used aid in the inflammation …

Diversity And Habitat Use Of Bats In Modified Suburban Landscapes, Brittany Morgera

Biology Presentations

Bats occupy critical ecological niches and perform important ecosystem services like controlling insect populations. However, humans have altered bat habitat substantially, resulting in the reduction of bat populations. The goals of this research are to assess bat diversity and habitat use across different levels of suburban habitat modification. To accomplish this, we deployed passive acoustic recorders at twelve locations with varying human impact in Montgomery County, Pennsylvania. In accordance with The North American Bat Monitoring Program’s standards, acoustic analysis software was used to identify bat species. Manual identification methods from The Canadian Wildlife Health Cooperative were used to verify these …

Dosage-Dependent, Carboplatin And Ng52 Show Synergistic Effect On Inhibiting Cell Proliferation In Breast Cancer Cell Line, Ben Couture, Ryan Zhuge

Biology Presentations

BT-549 (Breast Cancer), a highly invasive epithelial breast cancer cell line, was used to investigate the effects of two drugs: NG52, a selective kinase inhibitor and Carboplatin, a platinum-based DNA-alkylating agent. Using cell counting assays and calculating IC50 values, we examined their combined impact on cell proliferation. Results revealed both an antagonistic and synergistic effect dependent on concentration. Where the individual agents inhibited cell proliferation less effectively than expected. These findings show the complexity of drug interactions and provide insights into optimizing therapeutic strategies for highly invasive cancer types.

Fighting Modern Battles, Brawling A Breast Cancer From The Past: A New Combination Therapy Technique Combining A Platinum-Based Agent And Hdac Inhibition Agent, Matthew I. Hyder, Jackson D. Southern

Biology Presentations

Carboplatin and tucidinostat are two often-used chemotherapeutic drugs in combating cancers. After seeding BT-549 cells in vitro and single-drug treatments were completed, IC50 values and treatment curves were determined for both drugs with CompuSyn software. The Tucidinostat IC50 value of 0.28614 µM indicates effective 50% inhibitory activity at less than one micromolar. Carboplatin treatment revealed an IC50 value of 273.792 µM, indicating ineffective treatment. Combination therapy revealed an antagonistic effect with a CI50 value of 210.406. This may be due to experimental errors with pipetting or cell seeding, or drug-ailment mismatch.

Cutting Waste In Tupper's Restaurant, Logan Salvator, Christien Merritt, Lily Amaral, Erik Dukes

Earth Day Symposium on Climate and Sustainablity

No abstract provided.

Genome Analysis Of Aeromonas Hydrophila Strain S14-452, Zarin Tasnim Raya

Undergraduate Research Conference

The Aeromonas hydrophila are gram-negative, opportunistic bacteria that can infect many groups of organisms, mainly fish and amphibians. In channel catfish, A. hydrophila causes fatal bacterial septicemia, leading to massive economic losses for catfish farmers. Therefore, an understanding of its genome will aid in identifying its virulence factors, metabolic pathways and survival mechanisms within the host. This study details the draft genome sequence of A. hydrophila strain S14-452, isolated from channel catfish exhibiting bacterial septicemia during a disease outbreak at a catfish farm.

A. hydrophila strain S14-452 was sequenced using the Illumina iSeq 100 System. Assembly was performed with SPAdes, …

Sample Storage Method And Collection Time Effects On Horse Hair Cortisol Concentrations, Grace Robertson

Scholars Week

Serum cortisol concentration is the gold standard for evaluating stress in horses. However, it can be affected by circadian rhythms, environmental factors, and other excitatory events. Hair cortisol is less subject to these variables and is less invasive to collect, but there is a lack of published information on hair cortisol concentrations in horses. The objectives of this study were to examine 1) the impact of sample storage (Room temperature vs. Frozen) and 2) the effect of collection date (spring vs. fall), on cortisol concentration in equine hair. It was hypothesized that Frozen samples would yield higher concentrations than Room …

Improved Protein Splicing Through Viral Passaging, John Smetana

Scholars Week

Intervening proteins (inteins) are translated as subdomains within host proteins and removed through an intein-driven splicing reaction where the flanking sequences (exteins) are joined with a peptide bond. Previously, we developed a self-removing translation reporter for labeling Ebola virus (EBOV). In this reporter, an intein (RadA) containing the fluorescent protein ZsGreen (ZsG) is inserted within the EBOV protein VP30. Upon VP30-RadA-ZsG expression from the viral genome, RadA-ZsG is removed from VP30 through the protein splicing activity of RadA, generating functional, non-tagged VP30 and functional ZsGreen. While incorporation of our VP30-RadA-ZsG fusion reporter into recombinant EBOV (rEBOV- RadA-ZsG) resulted in an …