Life Sciences Commons^™

Rage Inhibition Reduces Timp And Decreases Cell Invasion In Cigarette Smoke Extract (Cse) Treated Oral Squamous Carcinoma Cells, Paul Reynolds

Annual Research Symposium

No abstract provided.

Rage Availability Lessens The Degree Of Dysfunctional Mitochondrial Bioenergetics Following Chronic Secondhand Smoke Exposure, Paul Reynolds

Annual Research Symposium

No abstract provided.

Gestational Dependent Responses To Second Hand Smoke (Shs) In Mouse Pregnancies, Paul Reynolds

Annual Research Symposium

No abstract provided.

Prevention Of Doxorubicin-Induced Cardiotoxicity By A Coumestan Analogue, Psoralidin, Mujtaba H. Shah, Myia Aiges, Kota V. Ramana

Annual Research Symposium

Natural phenolic compound Psoralidin limits cardiotoxicity associated with Doxorubicin

Foliar Application Of Acetic Acid And Effectiveness Against Drought At Different Time Points In Soybean (Glycine Max) Development, Miranda Rudolph, Megan Taylor Phd.

Posters-at-the-Capitol

Drought is arguably the most serious environmental factor affecting crop production today. A plant's response to drought stress is extremely complex, affecting numerous metabolic pathways that are all interconnected in their responses. Due to this complex nature, scientists do not fully understand the implications of different treatments and how they affect these processes. Acetic acid has been shown to improve plant growth and resistance to drought stress, but exactly how it accomplishes this is also unknown. Soybeans (Glycine max) are one of the most important crops worldwide and can suffer significant yield loss due to drought stress. As climate change …

How Will Climate Change Affect The Future, Ashanti K. Belone, Farrukh Zia

Publications and Research

Climate Change has played a massive role in the habitat of us earth dwellers and the animals that co-exists with us. I believe that essentially climate change plays a massive role because this can dictate whether or not the earth is habitable and if a need for evacuation is necessary. Many might believe that climate change only refers to the rising temperature but that’s just the icing on the cake. Earth is a system that is very much connected, this means that changes in one area will set off a chain reaction allowing these changes to happen in many other …

Foliar Application Of Acetic Acid And Effectiveness Against Drought At Different Time Points In Soybean Development, Miranda Rudolph

Scholars Week

Abstract

Drought is arguably the most serious environmental factor affecting crop production today. A plants response to drought stress is extremely complex, affecting numerous metabolic pathways that are all interconnected in their responses. Due to this complex nature, scientists do not fully understand the implications of different treatments and how they affect these processes. Acetic acid has been shown to improve plant growth and resistance to drought stress, but exactly how it accomplishes this is also unknown. Soybeans (Glycine max) are one of the most important crops worldwide and can suffer significant yield loss due to drought stress. As climate …

Sea-Phages Research Opportunity, Sarah Ballarin

Trick to the Treat of Internships and Research

Research opportunity targeted for freshmen and sophomores through the SEA-PHAGES program. The goal of the research is to discover new bacteriophages (viruses that infect bacteria) to help combat antibiotic resistance. Phage therapy is a promising alternative to conventional antibiotics. Phages have also been widely used in the food industry to prevent microbial growth on certain foods and are currently being explored as a method for bioremediation of oil spills and wastewater treatment.

Last year, my research team discovered two new bacteriophages: Genamy16 and NovaSharks that were able to infect the bacteria Gordonia rubripertincta. These phages can possibly be used for …

Science Alive, Trisha Sudhakar, Rajin Persaud

Trick to the Treat of Internships and Research

The goal of Science Alive is to provide a “sense of wonder” not only for the grade-school children but for the college students and their faculty as well. Science Alive serves to reinforce the scientific knowledge of local grade-school students and community members, while enhancing the education and career development opportunities for college students. Our group does this by providing opportunities for youth to explore science beyond the textbooks through hands-on, interactive discovery, which stimulates interest and fosters confidence for college and grade-school students alike. Our groups lead on-campus and in-class workshops, weekend clubs, after-school programs, and other community events. …

Pfizer Summer Growth Experience, Arman Kakkar

Trick to the Treat of Internships and Research

From May 9, 2022 till July 29, 2022, I served as a Research Intern at Pfizer. Specifically, I worked in the Vaccine Research and Development Sector in the High Throughput Clinical Immunoassays and Diagnostics Group (HCID). In this group, I was responsible for Phase 3 testing of clinical trial material for the Covid-19 Vaccine. Over this time, I learned a great deal about the process of vaccine production from start to finish. Additionally, I was able to make numerous connections. This is definitely an experience I would recommend to others.

Animal Frequency In The Presence & Absence Of Human Disturbance, Jade Riddle, Angel Stanley, Teresa Orellana

Fall Showcase for Research and Creative Inquiry

No abstract provided.

The Genetics Of Skin Cancer: What Genes Drive The Development Of Basal Cell Carcinoma, Squamous Cell Carcinoma, And Melanoma?, Cassandra Poole, Abagail Pack, Elizabeth Whitehead, Virginia Marshall

Fall Showcase for Research and Creative Inquiry

Skin cancer is one of the most common forms of cancer worldwide. The American Academy of Dermatology estimates that 9500 people in the United States are diagnosed with skin cancer every day, and that 1 in 5 Americans will be diagnosed with skin cancer by age 70. With such a high prevalence of disease, understanding how skin cancer develops and how it can be treated is extremely important. This project aims to analyze the genes involved in the development of the three most common forms of skin cancer: basal cell carcinoma, squamous cell carcinoma, and melanoma.

X-Ray And Mri Theory For Mineral-Rich Fruits Affected By Heat Waves During Climate Change, Daler Djuraev, Somdat Kissoon, Robert O'Brien, Nino Jvarishvil

Publications and Research

Conventional Nutrition facts data relays the amounts of different minerals in apples. This information from such analysis may not connect these minerals with their natural biochemical or functional state for health or disease. These minerals may also be part of different particle sizes that affects X-ray transmission, absorption and scatter. The minerals may also redistribute within the tissue over time with or without heat shock. Current Medical Imaging procedures (Xray and MRI) do not localize such minerals. Our work offers a way to increase detection sensitivity of transition metals in various apple varieties non-invasively. This can constitute a step in …

Genetic Diversity In Helianthus Annuus: Selective Breeding And Induced Mutagenesis, Dillon Holton

Thinking Matters Symposium

H. annuus, more commonly known as the sunflower, is a single species that has many different variations. Traits have been selectively bred for hundreds of years in order to produce a beautiful flower as well as essential agricultural products. Recently interest in the sunflower as a food and fuel crop has led to selective breeding of seeds that produce high yields of sunflower oil. To further push the limits of this plant's genome, researchers have used mutagenesis to force mutations in hopes of developing novel modifications that could increase yield. With the entire genome mapped, the goal for many research …

Investigation Of Oncogenic Ras And Endoplasmic Reticulum-Mitochondria Calcium Flux And Their Relationship In The Context Of Tumorigenesis, Emma Anderson

Liberty University Research Week

Undergraduate

Theoretical Proposal

The Presence Of Ehrlichia In White-Tailed Deer In Central Virginia, Brenna Kurtz

Liberty University Research Week

Undergraduate

Theoretical Proposal

Investigating Antimicrobial Chemicals Released From Developing Amphibian Eggs, Christian Sorensen, Abigail Piddock, Alexandria Hannah, Ciara Johnson, Connor Chapman

Liberty University Research Week

Undergraduate

Theoretical Proposal

Casein Kinases Are Required For The Stability Of The Glucose Sensing Receptor Rgt2 In Yeast, Danny Bloor

Liberty University Research Week

Undergraduate

Basic

Binding Affinities Of Bpa Derivatives To The Human Estrogen Receptor: Utilization And Assessment Of Autodock Vina, Luke Newman

Liberty University Research Week

Undergraduate

Basic

The Use Of Molecular Beacon Sirna To Induce Degradation Of Sars Cov-2 Mrna In Infected Cells, Katelynn Sepke, Hanna Dutt

Liberty University Research Week

Undergraduate

Basic

Casein Kinases Interact And Stabilize Glucose Sensing Receptors In Yeast, Julia Humble, Levi Mailloux, Sophia Adams

Liberty University Research Week

Undergraduate

Basic

Design, Synthesis, Cloning, And Expression Of Heme-Containing Peroxygenase From Cucurbita Moschata, Rebekah Walker

Liberty University Research Week

Undergraduate

Basic

Validating Methods For Monitoring Physiological Health Of Plethodon Hubrichti Along An Elevational Gradient, Taylor Salvigsen, Kyra Todd

Liberty University Research Week

Undergraduate

Basic

Characterizing The Cutaneous Microbiome Of Eurycea Lucifuga As A Potential Defense Against Infectious Diseases, Madeline Key, Mckenzie Perkins

Liberty University Research Week

Undergraduate

Basic

The Effect Of Bpc Exposure On Ikaros And Rag-1 Gene Expression In Zebrafish, Robert Fisher, Anna Osborn, Asia Eskaros, Michael Chembars, Pierce Knepley, Thomas Russell

Liberty University Research Week

Undergraduate

Basic

Comparison Of Training Load Between Ncaa Diii Tennis Resistance Training, Practices, And Competitions, Lauren Pascadlo

Student Scholar Showcase

Background: There are 7553 NCAA Division III tennis players, who play with less training coordination than elite players. Division III tennis load research is highly underdeveloped with most tennis research focusing on elite players. Additionally, practice training loads must be similar to match training loads so athletes are physically and mentally prepared for competition.

Purpose: To describe the training load in Division III tennis players during strength and conditioning, practices, and competition.

Methods: 7 Male and female division II tennis players attended 2 regularly scheduled practice, competition, and resistance training sessions. Training load was measured as external (GPS data consisting …

The Effect Of Ethanolic Echinacea Purpurea Root Extracts On The Production Of Pro-Inflammatory Mediators In Raw 264.7 Murine Macrophages, Trey T. Nguyen

Student Scholar Showcase

Echinacea purpurea, commonly known as the purple coneflower, is utilized in medicinal preparations due to potential immunostimulatory and anti-inflammatory properties. Present bioactive metabolites such as alkamides, polysaccharides, and caffeic acid derivatives provide pharmacological elements essential to mitigating symptoms produced by upper respiratory illnesses. The chemical composition of E. purpurea holds medicinal value, but there remains controversy surrounding the efficacy of its use in medicine. The purpose of this study is to examine the effects of an 75% ethanolic E. purpurea root extract on LPS (lipopolysaccharide)-stimulated RAW 264.7 murine macrophages. Treatment groups included ethanolic E. purpurea extract (3µL, 15µL, 30µL), …

Carbonyl Iron Vs Ferrous Sulfate On Blood Iron Markers In Male Division Iii Cross-Country Athletes, Sam Gunter

Student Scholar Showcase

Competitive distance runners are often predisposed to developing iron deficiency. This study aimed to determine if carbonyl iron was more effective at maintaining blood iron markers and minimizing overall fatigue and GI stress than ferrous sulfate. In this randomized, independent groups study, 7 male, division III cross-country athletes were supplemented with either carbonyl iron or ferrous sulfate for 6 weeks. Blood hemoglobin, hematocrit, subjective GI distress, subjective fatigue, and relative exertion of recent training were assessed at baseline, 3 and 6 weeks. Results will be analyzed via a detailed analysis of variance to determine significant differences in outcome measures. Statistical …

The Plant And The Pathogen: Elucidating The Relationship Between Root-Knot Nematodes, Ph Levels, And Arabidopsis Thaliana Development, Rachel Garnett

Student Scholar Showcase

Root-knot nematodes (RKNs) within the Meloidogyne genus are considered one of the largest threats to plant health and subsequent crop yield and profit (Forghani and Hajihassani 2020; Bernard et al. 2017). As a pest that presents global consequences, its mitigation through sustainable interventions may confer results for the treatment of similar plant pathogens. A member of the Brassicaeae family, Arabidopsis thaliana, was chosen for this study to determine plant responses to RKN-standard pH media. pH was varied between control and experimental groups, and phenotypic variables of primary root length and plant height were observed and analyzed. Wild-type Arabidopsis thaliana …

Investigating Alternative Induction Of The S. Aureus 80a Prophage, Jody Caretti

Student Scholar Showcase

Widespread antibiotic resistance has quickly become one of the most concerning crises affecting modern medicine, especially in cases of Staphylococcal infections, which have become resistant to all ��-lactam antibiotics. As a result, research into alternative forms of treatment for bacterial infections is a top priority. Bacteriophage therapy is a popular candidate for replacing antibiotics, due to the way the viruses interact with the bacteria. The 80�� prophage integrates its DNA into Staphylococcus aureus strain 10616 via the lysogenic cycle, and replicates with the bacterial cell. When stressed, the bacteria stop replicating and the prophage stimulates the lytic cycle, activating transcription …